Results 41 to 50 of about 272,990 (263)
Representing Earth Science Concepts through Slowmation: Influences on Conceptual Change
eTropic: electronic journal of studies in the tropics, 2015 It is well known that students arrive in science classrooms with pre-instructional ideas about science phenomena, and that often students’ ideas are not scientifically accurate representations of these phenomena.
Reece Mills +2 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Deep and lifelong learning: When theory and SoTL intersect
Journal of the Scholarship of Teaching and Learning, 2013 In this reflective essay, a teacher educator describes her own transformation that occurred as a result of studying adult learning theory along with a group of doctoral students.
Jane West
doaj
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Revista Eureka sobre Enseñanza y Divulgación de las Ciencias, 2011 La mayoría de los modelos de enseñanza del ámbito de la Didáctica de las Ciencias se han desarrollado en el marco de la analogía del alumno como científico.
Marín Martínez, Nicolás
doaj
Teaching for Conceptual Change in Security Awareness [PDF]
IEEE Security & Privacy Magazine, 2008 The ultimate goal of security awareness training is to make trainees adhere to safe computing practices. To meet this goal, training providers put much effort into designing the curriculum for security awareness programs. General computer users usually build their own ideas about computer security according to their daily usage and observations ...
Wei, VK, Chan, YY
openaire +3 more sources
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Ingredients for change: revisiting a conceptual framework [PDF]
Quality and Safety in Health Care, 2002 Finding ways to deliver care based on the best possible evidence remains an ongoing challenge. Further theoretical developments of a conceptual framework are presented which influence the uptake of evidence into practice. A concept analysis has been conducted on the key elements of the framework--evidence, context, and facilitation--leading to ...
Rycroft-Malone, J. +6 more
openaire +3 more sources