Results 11 to 20 of about 790 (211)

Examining Cocaine Conditioning Place Preference in Mice [PDF]

BIO-PROTOCOL, 2020
A key component of combating substance use disorders is understanding the neural mechanisms that support drug reward. Tasks such as self-administration assess the reinforcing properties of a drug using a learned behavior but require numerous training sessions and surgery.
MaryElizabeth Simkevich, Rianne Campbell, André White   +2 more
openaire   +3 more sources

Conditioned place preference successfully established in typically developing children

Frontiers in Behavioral Neuroscience, 2015
Affective processing, known to influence attention, motivation and emotional regulation is poorly understood in young children, especially for those with neurodevelopmental disorders characterized by language impairments.
Leah T Hiller, Sandy eTakata, Barbara L Thompson, Barbara L Thompson, Barbara L Thompson   +4 more
doaj   +1 more source

Corticosterone fails to produce conditioned place preference or conditioned place aversion in rats [PDF]

Behavioural Brain Research, 2007
In some rats, the hormone corticosterone is reinforcing. High novelty-seeking rats (high responders, HR) self-administered corticosterone at a much higher rate than low novelty-seeking rats (low responders, LR) do [Piazza PV, Deroche V, Deminiere JM, Maccari S, Le Moal M, Simon H, Corticosterone in the range of stress-induced levels possesses ...
David, Dietz, Hui, Wang, Mohamed, Kabbaj
openaire   +2 more sources

Lack of rewarding effects of a soluble epoxide hydrolase inhibitor TPPU in mice: Comparison with morphine

Neuropsychopharmacology Reports, 2020
Aim Although opioids have been used as treatment of neuropathic pain, opioids have abuse potential in humans. Since soluble epoxide hydrolase (sEH) in the metabolism of polyunsaturated fatty acids plays a key role in the pain, sEH inhibitors would be ...
Xiayun Wan, Yuko Fujita, Lijia Chang, Yan Wei, Li Ma, Gerile Wuyun, Yaoyu Pu, Bruce D. Hammock, Kenji Hashimoto   +8 more
doaj   +1 more source

Melatonin attenuates morphine‐induced conditioned place preference in Wistar rats

Brain and Behavior, 2021
Purpose Morphine is the predominantly used drug for postoperative and cancer pain management. However, the abuse potential of morphine is the primary disadvantage of using opioids in pain management.
Fahad S. Alshehri, Badrah S. Alghamdi, Alqassem Y. Hakami, Abdullah A. Alshehri, Yusuf S. Althobaiti   +4 more
doaj   +1 more source

Intolerance of uncertainty and conditioned place preference in opioid addiction [PDF]

PeerJ, 2018
Several personality factors have been implicated in vulnerability to addiction by impacting learning and decision making. One such factor is intolerance of uncertainty (IU), the tendency to perceive uncertain situations negatively and avoid them ...
Milen L. Radell, Michael Todd Allen, Belinda Favaloro, Catherine E. Myers, Paul Haber, Kirsten Morley, Ahmed A. Moustafa   +6 more
doaj   +2 more sources

Ibogaine Blocks Cue- and Drug-Induced Reinstatement of Conditioned Place Preference to Ethanol in Male Mice

Frontiers in Pharmacology, 2021
Ibogaine is a psychedelic extracted from the plant Tabernanthe iboga Baill. (Apocynaceae), natural from Africa, and has been proposed as a potential treatment for substance use disorders.
Gabrielle M. Henriques, Alexia Anjos-Santos, Alexia Anjos-Santos, Isa R. S. Rodrigues, Victor Nascimento-Rocha, Henrique S. Reis, Matheus Libarino-Santos, Thaísa Barros-Santos, Thais S. Yokoyama, Natalia B. Bertagna, Cristiane A. Favoretto, Célia R. G. Moraes, Fábio C. Cruz, Paulo C. R. Barbosa, Eduardo A. V. Marinho, Alexandre J. Oliveira-Lima, Laís F. Berro, Laís F. Berro   +17 more
doaj   +1 more source

Conditioned place preference training prevents hippocampal depotentiation in an orexin-dependent manner

Journal of Biomedical Science, 2017
Background Long-term potentiation (LTP) is well recognized as a cellular-correlated synaptic plasticity of learning and memory. However, its reversal forms of synaptic plasticity, depotentiation, is less studied and its association with behaviors is also
Guan-Ling Lu, Hau-Jie Yau, Lih-Chu Chiou
doaj   +1 more source

Novel Putative Positive Modulators of α4β2 nAChRs Potentiate Nicotine Reward-Related Behavior

Molecules, 2021
The popular tobacco and e-cigarette chemical flavorant (−)-menthol acts as a nonselective, noncompetitive antagonist of nicotinic acetylcholine receptors (nAChRs), and contributes to multiple physiological effects that exacerbates nicotine addiction ...
Skylar Y. Cooper, Austin T. Akers, Velvet Blair Journigan, Brandon J. Henderson   +3 more
doaj   +1 more source

Low current intensity plus an ineffective dose of morphine affect conditioning place preference through different pathways in the lateral habenula

Advanced Biomedical Research, 2023
Background: The involvement of lateral habenula and the ineffective dose of morphine on reward-related learning and memory is less well-known. This study looked into the effects of electrical stimulation, GABAB receptor blockade, and a combination of ...
Elahe Amohashemi, Parham Reisi, Hojjat Allah Alaei   +2 more
doaj   +1 more source