Results 11 to 20 of about 22,902 (258)
Conditioned place preference behavior in zebrafish [PDF]
Nature Protocols, 2011 This protocol describes conditioned place preference (CPP) in zebrafish following a single exposure to a substance. In the CPP paradigm, animals show a preference for an environment that has previously been associated with a substance (drug), thus indicating the positive-reinforcing qualities of that substance.
Priya, Mathur, Billy, Lau, Su, Guo
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Running Reward Conditioned Place Preference Task
Bio-Protocol, 2016 The conditioned place preference (CPP) test is a standard pre-clinical behavioral tool used to study the motivational effects of drugs and non-drug treatments in experimental animals.
Maria Fernandes, Stephanie Fulton
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Examining Cocaine Conditioning Place Preference in Mice [PDF]
BIO-PROTOCOL, 2020 A key component of combating substance use disorders is understanding the neural mechanisms that support drug reward. Tasks such as self-administration assess the reinforcing properties of a drug using a learned behavior but require numerous training sessions and surgery.
MaryElizabeth Simkevich +2 more
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Conditioned place preference successfully established in typically developing children
Frontiers in Behavioral Neuroscience, 2015 Affective processing, known to influence attention, motivation and emotional regulation is poorly understood in young children, especially for those with neurodevelopmental disorders characterized by language impairments.
Leah T Hiller +4 more
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Neuropsychopharmacology Reports, 2020 Aim Although opioids have been used as treatment of neuropathic pain, opioids have abuse potential in humans. Since soluble epoxide hydrolase (sEH) in the metabolism of polyunsaturated fatty acids plays a key role in the pain, sEH inhibitors would be ...
Xiayun Wan +8 more
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Corticosterone fails to produce conditioned place preference or conditioned place aversion in rats [PDF]
Behavioural Brain Research, 2007 In some rats, the hormone corticosterone is reinforcing. High novelty-seeking rats (high responders, HR) self-administered corticosterone at a much higher rate than low novelty-seeking rats (low responders, LR) do [Piazza PV, Deroche V, Deminiere JM, Maccari S, Le Moal M, Simon H, Corticosterone in the range of stress-induced levels possesses ...
David, Dietz, Hui, Wang, Mohamed, Kabbaj
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Melatonin attenuates morphine‐induced conditioned place preference in Wistar rats
Brain and Behavior, 2021 Purpose Morphine is the predominantly used drug for postoperative and cancer pain management. However, the abuse potential of morphine is the primary disadvantage of using opioids in pain management.
Fahad S. Alshehri +4 more
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Advanced Biomedical Research, 2023 Background: The involvement of lateral habenula and the ineffective dose of morphine on reward-related learning and memory is less well-known. This study looked into the effects of electrical stimulation, GABAB receptor blockade, and a combination of ...
Elahe Amohashemi +2 more
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Intolerance of uncertainty and conditioned place preference in opioid addiction [PDF]
PeerJ, 2018 Several personality factors have been implicated in vulnerability to addiction by impacting learning and decision making. One such factor is intolerance of uncertainty (IU), the tendency to perceive uncertain situations negatively and avoid them ...
Milen L. Radell +6 more
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Journal of Biomedical Science, 2017 Background Long-term potentiation (LTP) is well recognized as a cellular-correlated synaptic plasticity of learning and memory. However, its reversal forms of synaptic plasticity, depotentiation, is less studied and its association with behaviors is also
Guan-Ling Lu, Hau-Jie Yau, Lih-Chu Chiou
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