Results 11 to 20 of about 197,171 (310)

Examining Cocaine Conditioning Place Preference in Mice [PDF]

BIO-PROTOCOL, 2020
A key component of combating substance use disorders is understanding the neural mechanisms that support drug reward. Tasks such as self-administration assess the reinforcing properties of a drug using a learned behavior but require numerous training sessions and surgery.
MaryElizabeth Simkevich, Rianne Campbell, André White   +2 more
openaire   +3 more sources

Differences in the Alcohol Preference Assessment of Shy and Bold Zebrafish

Frontiers in Behavioral Neuroscience, 2022
Individuals differ in their preference for alcohol and propensity to develop alcoholism, where the behavioral profile, such as the bold-shy axis, plays an important role for such a difference.
Marina Sanson Bellot, Marina Sanson Bellot, Isabela Inforzato Guermandi, Bruno Camargo-dos-Santos, Bruno Camargo-dos-Santos, Percília Cardoso Giaquinto, Percília Cardoso Giaquinto   +6 more
doaj   +1 more source

Conditioned place preference behavior in zebrafish [PDF]

Nature Protocols, 2011
This protocol describes conditioned place preference (CPP) in zebrafish following a single exposure to a substance. In the CPP paradigm, animals show a preference for an environment that has previously been associated with a substance (drug), thus indicating the positive-reinforcing qualities of that substance.
Priya, Mathur, Billy, Lau, Su, Guo
openaire   +2 more sources

mGluR5 knockout mice exhibit normal conditioned place-preference to cocaine [PDF]

, 2011
Metabotropic glutamate receptor 5 (mGluR5) null mutant (-/-) mice have been reported to totally lack the reinforcing or locomotor stimulating effects of cocaine.
Andrew L. Varnell, Donald C. Cooper, Melissa A. Fowler   +2 more
core   +2 more sources

Single prazosin infusion in prelimbic cortex Fosters extinction of amphetamine-induced conditioned place preference [PDF]

, 2017
Exposure to drug-associated cues to induce extinction is a useful strategy to contrast cue-induced drug seeking. Norepinephrine (NE) transmission in medial prefrontal cortex has a role in the acquisition and extinction of conditioned place preference ...
Alessandro Rava, Emanuele C. Latagliata, Giulia Chiacchierini, Luisa Lo Iacono, Luisa Lo Iacono, Marco Sancandi, Stefano Puglisi-Allegra, Stefano Puglisi-Allegra, Valeria Oliva   +8 more
core   +4 more sources

Corticosterone Potentiation of Cocaine-Induced Reinstatement of Conditioned Place Preference in Mice is Mediated by Blockade of the Organic Cation Transporter 3 [PDF]

, 2016
The mechanisms by which stressful life events increase the risk of relapse in recovering cocaine addicts are not well understood. We previously reported that stress, via elevated corticosterone, potentiates cocaine-primed reinstatement of cocaine seeking
A Amphoux, A Schmitt, Analisa Taylor, BA Nic Dhonnchadha, Beliz Kurtoglu, Brittany Nino, D Gründemann, D Gründemann, D Gründemann, DA Baker, David A Baker, DM Platt, E Schomig, EN Graf, F Martel, G Horvath, H Duan, HW Shen, Jayme R McReynolds, JJ Burmeister, JL Malisch, John R Mantsch, JR Mantsch, JR McReynolds, K Engel, LC Daws, LL Iversen, M Aliczki, M Cui, N Baganz, NL Baganz, O Vranjkovic, Oliver Vranjkovic, Olivia Derricks, Paul J Gasser, PJ Fletcher, PJ Gasser, PJ Gasser, R Sinha, R Sinha, R Zwart, Robert A Wheeler, S Erb, S Gong, SZ Langer, T Lenz, T Shang, Terra Ambrosius, V Gorboulev, V Vialou, V Vialou, XY Zhang   +51 more
core   +2 more sources

Conditioned place preference successfully established in typically developing children

Frontiers in Behavioral Neuroscience, 2015
Affective processing, known to influence attention, motivation and emotional regulation is poorly understood in young children, especially for those with neurodevelopmental disorders characterized by language impairments.
Leah T Hiller, Sandy eTakata, Barbara L Thompson, Barbara L Thompson, Barbara L Thompson   +4 more
doaj   +1 more source

Lack of rewarding effects of a soluble epoxide hydrolase inhibitor TPPU in mice: Comparison with morphine

Neuropsychopharmacology Reports, 2020
Aim Although opioids have been used as treatment of neuropathic pain, opioids have abuse potential in humans. Since soluble epoxide hydrolase (sEH) in the metabolism of polyunsaturated fatty acids plays a key role in the pain, sEH inhibitors would be ...
Xiayun Wan, Yuko Fujita, Lijia Chang, Yan Wei, Li Ma, Gerile Wuyun, Yaoyu Pu, Bruce D. Hammock, Kenji Hashimoto   +8 more
doaj   +1 more source

Naloxone blockade of amphetamine place preference conditioning [PDF]

Psychopharmacology, 1991
Amphetamine and naloxone were examined in place conditioning, in order to study possible interactions between endogenous opioids and catecholamines in reinforcement. After initial preferences were determined, animals were conditioned with amphetamine alone (1.0 mg/kg SC), naloxone alone (0.02, 0.2 or 2.0 mg/kg SC) or combinations of amphetamine plus ...
Belluzzi, James D., Trujillo, Keith A., Stein, Larry   +2 more
openaire   +3 more sources

Melatonin attenuates morphine‐induced conditioned place preference in Wistar rats

Brain and Behavior, 2021
Purpose Morphine is the predominantly used drug for postoperative and cancer pain management. However, the abuse potential of morphine is the primary disadvantage of using opioids in pain management.
Fahad S. Alshehri, Badrah S. Alghamdi, Alqassem Y. Hakami, Abdullah A. Alshehri, Yusuf S. Althobaiti   +4 more
doaj   +1 more source