Results 21 to 30 of about 4,305,638 (286)
Frontiers in Pharmacology, 2021 Ibogaine is a psychedelic extracted from the plant Tabernanthe iboga Baill. (Apocynaceae), natural from Africa, and has been proposed as a potential treatment for substance use disorders.
Gabrielle M. Henriques +17 more
doaj +1 more source
Intolerance of uncertainty and conditioned place preference in opioid addiction [PDF]
PeerJ, 2018 Several personality factors have been implicated in vulnerability to addiction by impacting learning and decision making. One such factor is intolerance of uncertainty (IU), the tendency to perceive uncertain situations negatively and avoid them ...
Milen L. Radell +6 more
doaj +2 more sources
Novel Putative Positive Modulators of α4β2 nAChRs Potentiate Nicotine Reward-Related Behavior
Molecules, 2021 The popular tobacco and e-cigarette chemical flavorant (−)-menthol acts as a nonselective, noncompetitive antagonist of nicotinic acetylcholine receptors (nAChRs), and contributes to multiple physiological effects that exacerbates nicotine addiction ...
Skylar Y. Cooper +3 more
doaj +1 more source
Journal of Biomedical Science, 2017 Background Long-term potentiation (LTP) is well recognized as a cellular-correlated synaptic plasticity of learning and memory. However, its reversal forms of synaptic plasticity, depotentiation, is less studied and its association with behaviors is also
Guan-Ling Lu, Hau-Jie Yau, Lih-Chu Chiou
doaj +1 more source
Opposite effects of MK-801 on the expression of food and morphine-induced conditioned place preference in rats [PDF]
, 2006 Behavioural studies have provided strong evidence for common substrates in the rewards of natural and addictive substances, but it is still unclear whether there is a common glutamatergic NMDA receptor mechanism involved in the processing of reward for ...
Zheng, XG +5 more
core +1 more source
Advanced Biomedical Research, 2023 Background: The involvement of lateral habenula and the ineffective dose of morphine on reward-related learning and memory is less well-known. This study looked into the effects of electrical stimulation, GABAB receptor blockade, and a combination of ...
Elahe Amohashemi +2 more
doaj +1 more source
Parvalbumin Interneurons Determine Emotional Valence Through Modulating Accumbal Output Pathways
Frontiers in Behavioral Neuroscience, 2019 Parvalbumin (PV) expressing GABAergic interneurons provide large source of GABA to spiny projection neurons (SPNs) in the striatum. However, the roles of PV+ interneurons in the regulation of SPNs in the ventral striatum and emotional states are largely ...
Xi Chen +4 more
doaj +1 more source
Brain Sciences, 2012 Reinstatement of conditioned place preferences have been used to investigate physiological mechanisms mediating drug-seeking behavior in adolescent and adult rodents; however, it is still unclear how psychostimulant exposure during adolescence affects ...
Kimberly A. Badanich, Cheryl L. Kirstein
doaj +1 more source
PLoS ONE, 2014 The function of TRPV1 (transient receptor potential vanilloid subfamily, member 1) in the central nervous system is gradually elucidated. It has been recently proved to be expressed in nucleus accumbens (NAc), a region playing an essential role in ...
Li-Jun Heng +8 more
doaj +1 more source
Learning a non-neutral conditioned stimulus: place preference in the crab Neohelice granulata
, 2021 In the wild, being able to recognize and remember specific locations related to food sources and the associated attributes of landmarks is a cognitive trait important for survival.
Klappenbach, Martín +2 more
core +1 more source