Results 21 to 30 of about 790 (211)

Naloxone blockade of amphetamine place preference conditioning [PDF]

Psychopharmacology, 1991
Amphetamine and naloxone were examined in place conditioning, in order to study possible interactions between endogenous opioids and catecholamines in reinforcement. After initial preferences were determined, animals were conditioned with amphetamine alone (1.0 mg/kg SC), naloxone alone (0.02, 0.2 or 2.0 mg/kg SC) or combinations of amphetamine plus ...
Belluzzi, James D., Trujillo, Keith A., Stein, Larry   +2 more
openaire   +3 more sources

Parvalbumin Interneurons Determine Emotional Valence Through Modulating Accumbal Output Pathways

Frontiers in Behavioral Neuroscience, 2019
Parvalbumin (PV) expressing GABAergic interneurons provide large source of GABA to spiny projection neurons (SPNs) in the striatum. However, the roles of PV+ interneurons in the regulation of SPNs in the ventral striatum and emotional states are largely ...
Xi Chen, Zhiyuan Liu, Chaonan Ma, Lan Ma, Xing Liu   +4 more
doaj   +1 more source

Cocaine-Induced Reinstatement of a Conditioned Place Preference in Developing Rats: Involvement of the D2 Receptor

Brain Sciences, 2012
Reinstatement of conditioned place preferences have been used to investigate physiological mechanisms mediating drug-seeking behavior in adolescent and adult rodents; however, it is still unclear how psychostimulant exposure during adolescence affects ...
Kimberly A. Badanich, Cheryl L. Kirstein
doaj   +1 more source

Blocking TRPV1 in nucleus accumbens inhibits persistent morphine conditioned place preference expression in rats.

PLoS ONE, 2014
The function of TRPV1 (transient receptor potential vanilloid subfamily, member 1) in the central nervous system is gradually elucidated. It has been recently proved to be expressed in nucleus accumbens (NAc), a region playing an essential role in ...
Li-Jun Heng, Bo Huang, Heng Guo, Lian-Ting Ma, Wei-Xin Yuan, Jian Song, Peng Wang, Guo-Zheng Xu, Guo-Dong Gao   +8 more
doaj   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

Re‐Irradiation in Pediatric Diffuse Midline Glioma: A Multi‐Institutional Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with recurrent diffuse midline gliomas (DMGs) have limited therapeutic options at recurrence. Re‐irradiation (RT2) may be used at progression, but with uncertainty about the benefit. Methods We conducted a multi‐institutional retrospective study of children aged < 18 with DMG treated at three centers (Toronto, Canada ...
Ajay Thomas Alex, Sean P. Hassan, Helen Benghiat, Liam Herbert, Jennifer Adamski, Shivani Bailey, Claire Esler, Louise Brookes, Molly Bamber, Grace Koudou, Karen Waite, Julie Bennett, Anirban Das, Derek S. Tsang   +13 more
wiley   +1 more source

Place conditioning as evaluation of affective valence in piglets

Scientific Reports
The emotional valence of animals is challenging to assess, despite being a key component of welfare. In this study, we attempted to assess emotional valence through memory in 1- and 3-week-old piglets.
Thomas Ede, Sarah Ibach, Thomas D. Parsons   +2 more
doaj   +1 more source

Potential of Pramipexole in Attenuating Morphine Dependence: Insights from a Conditioned Place Preference Study in Mice

Cerrahpaşa Medical Journal
Objective: Pramipexole, a selective dopamine D2/D3 receptor agonist, has been implicated in modulating dopaminergic transmission in brain reward circuits.
Andleeb Shahzadi, Oruç Yunusoğlu, Mohamad Alhakim, Selim Gökdemir, Rüveyda Rümeysa Ateşoğlu   +4 more
doaj   +1 more source

Conditioned place preference of kisspeptin-10

Reviews on Clinical Pharmacology and Drug Therapy, 2021
INTRODUCTION: Kisspeptins (KISS), a group of brain neuropeptides are involved in sexual behavior. KISS activate the hypothalamic neurons that synthesize gonadotropin releasing hormone. KISS was also detected in the limbic system. Earlier, we showed the activation of sexual motivation after the administration of kisspeptin-10 without increasing the ...
Ilia Yu. Tissen, Polina A. Chepik, Andrei A. Lebedev, Leila A. Magarramova, Eugenii R. Bychkov, Petr D. Shabanov   +5 more
openaire   +1 more source

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source