Results 51 to 60 of about 197,171 (310)

Behavioral and molecular analysis of nicotine-conditioned place preference in zebrafish. [PDF]

open access: yesPLoS ONE, 2013
Studies using mice and rats have demonstrated that nicotine induces a conditioned place preference (CPP), with more effective results obtained by using biased procedures.
Ximena Kedikian   +2 more
doaj   +1 more source

Effects of Early-Adolescent, Mid-Adolescent, or Adult Stress on Morphine Conditioned Place Preference [PDF]

open access: yes, 2017
Early-life stress is correlated with negative mental health outcomes, including illicit drug abuse. One mechanism that may contribute to drug abuse is stress-induced elevation of drug reward.
Bakner, Lee   +2 more
core   +1 more source

Tonic inhibition of accumbal spiny neurons by extrasynaptic 4 GABAA receptors modulates the actions of psychostimulants [PDF]

open access: yes, 2014
Within the nucleus accumbens (NAc), synaptic GABAA receptors (GABAARs) mediate phasic inhibition of medium spiny neurons (MSNs) and influence behavioral responses to cocaine.
Belelli, D   +8 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Effects of aqueous saffron extract (Crocus sativus L.) on the acquisition and reinstatement of morphine-induced conditioned place preference in mice [PDF]

open access: yesAvicenna Journal of Phytomedicine, 2011
Objective: In the present study, the effects of aqueous saffron extract (Crocus sativus L.) on the acquisition and reinstatement of morphine-induced conditioned place preference (CPP) in mice were investigated.
Hossein Hosseinzadeh   +2 more
doaj  

Ketamine Blocks Morphine-Induced Conditioned Place Preference and Anxiety-Like Behaviors in Mice

open access: yesFrontiers in Behavioral Neuroscience, 2020
Patients suffering from opioid use disorder often relapse during periods of abstinence, which is posited to be caused by negative affective states that drive motivated behaviors.
Greer McKendrick   +9 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Behavior and hippocampal Epac signaling to nicotine CPP in mice

open access: yesTranslational Neuroscience, 2019
Tobacco use is a major challenge to public health in the United States and across the world. Many studies have demonstrated that adult men and women differ in their responses to tobacco smoking, however neurobiological studies about the effect of smoking
Liu Jing   +7 more
doaj   +1 more source

Effect of electrical stimulation of nucleus accumbens with low, median and high currents intensities on conditioned place preference induced by morphine in rats

open access: yesAdvanced Biomedical Research, 2014
Background: Some investigators indicated the effect of electrical or chemical stimulation on different parts of the brain and its effect on animal′s behaviors.
Maryam Radahmadi   +4 more
doaj   +1 more source

IKT az óvodában : kihívások és lehetőségek [PDF]

open access: yes, 2015
We suggest a new placebo analgesia animal model and investigated the role of the dopamine and opioid systems in placebo analgesia. Before and after the conditioning, we conducted a conditioned place preference (CPP) test to measure preferences for the ...
Chae, Younbyoung   +5 more
core   +1 more source

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