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Metrazol produces conditioned taste aversion in rats

Psychopharmacology, 1980
Employing a two bottle drinking procedure where an animal's preference is measured between plain water and a novel fluid, it was found that the convulsant drug Metrazol produced a conditioned taste aversion to saccharin. This finding is contrary to that of previous reports and highlights the sensitivity of the two bottle method in detecting a taste ...
P, Golus, R, McGee
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Conditioned taste aversion

2002
Abstract Farmers know, probably from the dawn of farming, that animals tend to avoid poisonous bait if they survive their first encounter with it. The farmers themselves may have probably noticed that foodstuff comes to evoke disgust if consuming it results in nausea and intestinal distress.
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The parabrachial nucleus and conditioned taste aversion

Brain Research Bulletin, 1999
The parabrachial nucleus (PBN) surrounds the brachium conjunctivum in the dorsolateral pons. Although composed of numerous subnuclei, the PBN is typically organized into medial and lateral subdivisions according to their location relative to the brachium.
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In utero taste/odor aversion conditioning in the rat

Physiology & Behavior, 1982
Rat fetuses exposed to a taste-odor stimulus and an aversive stimulus in utero showed an aversion to the taste/odor stimulus when tested 16 days postnatally. Fetuses which received various control treatments in utero did not show an aversion. These data show that rat fetuses at 20 days of gestation are capable of associative learning which can be ...
G, Stickrod   +2 more
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Magnetic Field Conditioned Taste Aversion In Rats

Physiology and Behavior, 1998
Conditioned taste aversion is a common classic conditioning procedure used to identify noxious stimuli. When a rat is given a taste solution, the conditioned stimulus (CS), followed by an unpleasant experience, the unconditioned stimulus (US), the rat will avoid consumption of the CS in future presentations.
David W Pittman
exaly   +3 more sources

Modulation of conditioned taste aversion by sodium pentobarbital

Pharmacology Biochemistry and Behavior, 1980
The effects of pentobarbital on the formation and expression of LiCl induced taste aversion were examined using a two-bottle preference test. Rats adapted to restricted fluid intake were offered a 15% sucrose solution 15 min after a pentobarbital or saline injection but prior to post-CS LiCl or control injections.
J T, Concannon, J, Freda
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Conditioned taste aversion as a learning and memory paradigm

Behavioural Brain Research, 2001
Conditioned taste aversion (CTA) is a well established learning and memory paradigm in rats and mice that is considered to be a special form of classical conditioning. Rodents--as well as many other species including man--learn to associate a novel taste (CS) with nausea (US), and as a consequence avoid drinking fluid with this specific taste.
Welzl H, D'Adamo P, Lipp HP
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Amount consumed and the formation of conditioned taste aversions

Behavioral Biology, 1977
Animals were allowed to drink 0.5, 1.5, 5.5, 6.5, or 10.5 ml of a 0.15% (w/v) solution of sodium saccharin prior to an injection of LiCl. Results of a 10-min test, administered 3 days after conditioning, showed that, up to and including 5.5 ml, animals that drank more on the training day formed stronger aversions.
N S, Braveman, J, Crane
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Conditioned taste aversion and the pituitary-adrenal system

Behavioral Biology, 1976
Plasma corticosterone levels of male rats were found to be elevated for 2–4 hr following injection of a toxic dosage of LiCl, while pretreatment with dexamethasone suppressed this pituitary-adrenal activation. These data suggest that both ACTH and corticosteroid levels are elevated at the time of taste aversion conditioning.
J W, Hennessy   +2 more
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Universality of parabrachial mediation of conditioned taste aversion

Behavioural Brain Research, 1994
Disruption of conditioned taste aversion (CTA) by tetrodotoxin (TTX) blockade of parabrachial nuclei elicited after ingestion of the gustatory CS and before administration of the visceral US is revealed by unchanged CS preference in retrieval test performed two days after acquisition. The universality of the above amnesia was examined in rats.
E, Bielavska, J, Bures
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