Results 51 to 60 of about 120,420 (290)

Multiscale methods for problems with complex geometry

, 2016
We propose a multiscale method for elliptic problems on complex domains, e.g. domains with cracks or complicated boundary. For local singularities this paper also offers a discrete alternative to enrichment techniques such as XFEM. We construct corrected
Elfverson, Daniel, Larson, Mats G., Målqvist, Axel   +2 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Prediction of Conducted Emission in a Switching Circuit With Cascaded Black-Box Networks Using Harmonic Impedance

IEEE Access
Predicting conducted emissions from switching circuits is challenging because switching actions make their device behavior periodically time-varying and induces harmonic coupling among frequency components.
Junhee Han, Wansoo Nah
doaj   +1 more source

Differential Beat Accuracy for ECG Family Classification Using Machine Learning

IEEE Access, 2022
Holter systems record the electrocardiogram (ECG), which is used to identify beat families according to their origin and severity. Many systems have been proposed using signal conditioning and machine learning (ML) classification algorithms for beat ...
Alba Vadillo-Valderrama, Rebeca Goya-Esteban, Raul P. Caulier-Cisterna, Arcadi Garcia-Alberola, Jose Luis Rojo-Alvarez   +4 more
doaj   +1 more source

Lower and Upper Conditioning in Quantum Bayesian Theory [PDF]

, 2018
Updating a probability distribution in the light of new evidence is a very basic operation in Bayesian probability theory. It is also known as state revision or simply as conditioning.
Jacobs, Bart
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Conditioned limit theorems for products of random matrices [PDF]

Probability Theory and Related Fields, 2016
Consider the product $G_{n}=g_{n} ... g_{1}$ of the random matrices $g_{1},...,g_{n}$ in $GL(d,\mathbb{R}) $ and the random process $ G_{n}v=g_{n}... g_{1}v$ in $\mathbb{R}^{d}$ starting at point $v\in \mathbb{R}^{d}\smallsetminus \{0\} .$ It is well known that under appropriate assumptions, the sequence $(\log \Vert G_{n}v\Vert)_{n\geq 1}$ behaves ...
Grama, Ion, Le Page, Émile, Peigné, Marc   +2 more
openaire   +4 more sources

A family of centered random walks on weight lattices conditioned to stay in Weyl chambers [PDF]

, 2016
Under a natural asumption on the drift, the law of the simple random walk on the multidimensional first quadrant conditioned to always stay in the first octant was obtained by O'Connell in [O].
Despax, Vivien
core   +2 more sources

Graphical Markov models, unifying results and their interpretation

, 2015
Graphical Markov models combine conditional independence constraints with graphical representations of stepwise data generating processes.The models started to be formulated about 40 years ago and vigorous development is ongoing.
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core   +1 more source