Results 61 to 70 of about 251 (211)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Distributed Nash Equilibrium Seeking for Aggregative Games With Linear Convergence Over Digraphs

IEEE Access
Aggregative games over directed networks are considered in this paper, where each player aims to minimize its cost function related to its own decision variables and the aggregate of all the players’ decision variables.
Qingyue Wu
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Condition numbers of Hessenberg companion matrices

Czechoslovak Mathematical Journal
The Fiedler matrices are a large class of companion matrices that include the well-known Frobenius companion matrix. The Fiedler matrices are part of a larger class of companion matrices that can be characterized with a Hessenberg form. In this paper, we demonstrate that the Hessenberg form of the Fiedler companion matrices provides a straight-forward ...
Cox, Michael, Vander Meulen, Kevin N., Van Tuyl, Adam, Voskamp, Joseph   +3 more
openaire   +3 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Potentiometric Determination of Chlorpromazine HCl Using Carbon Paste Electrode in Pure and Pharmaceutical Preparations

International Journal of Electrochemical Science, 2012
Carbon paste electrode has been developed for the potentiometric determination of chlorpromazine HCl drug. This work has focused on the fabrication of carbon paste ion selective electrode for determination of the drug under investigation using ...
Eman Y.Z. Frag, M.A. Zayed, M.M. Omar, Sally E.A. Elashery, Gehad G. Mohamed   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Macroscale coupling between structural and effective connectivity in the mouse brain

Scientific Reports
Exploring how the emergent functional connectivity (FC) relates to the underlying anatomy (structural connectivity, SC) is one of the major goals of modern neuroscience.
Danilo Benozzo, Giorgia Baron, Ludovico Coletta, Alessandro Chiuso, Alessandro Gozzi, Alessandra Bertoldo   +5 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

The Szegő condition for Coulomb Jacobi matrices

Journal of Approximation Theory, 2003
A Jacobi matrix with $a_n\to 1$, $b_n\to 0$ and spectral measure $ν'(x)dx + dν_{sing}(x)$ satisfies the Szeg\H o condition if $\int_{0}^π\ln \bigl[ ν'(2\cosθ) \bigr] dθ$ is finite. We prove that if $a_n = 1 + \frac α{n} + O(n^{-1-\eps})$ and $b_n = \frac β{n} + O(n^{-1-\eps})$ with $2α\ge |β|$ and $\eps>0$, then the corresponding matrix is Szeg\H o.
openaire   +2 more sources