Results 71 to 80 of about 120,420 (290)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Efficiency improvement of the frequency-domain BEM for rapid transient elastodynamic analysis
, 2013 The frequency-domain fast boundary element method (BEM) combined with the exponential window technique leads to an efficient yet simple method for elastodynamic analysis.
Wen, Lihua, Xiao, Jinyou, Ye, Wenjing
core +2 more sources
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Correction: Condition Number Estimation of Preconditioned Matrices
PLOS ONE, 2015 [This corrects the article DOI: 10.1371/journal.pone.0122331.].
openaire +3 more sources
On GMRES for singular EP and GP systems
, 2018 In this contribution, we study the numerical behavior of the Generalized Minimal Residual (GMRES) method for solving singular linear systems. It is known that GMRES determines a least squares solution without breakdown if the coefficient matrix is range ...
Morikuni, Keiichi, Rozložník, Miroslav
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Ingeniare: Revista Chilena de Ingeniería, 2008 Se estudia la influencia de la topología de redes eléctricas y alimentadores en el condicionamiento de las matrices asociadas a su modelado matemático. Se observa que el número de condición de estas matrices tiene una gran dependencia de la estructura de
Miguel Arias Albornoz +2 more
doaj
On The Frobenius Condition Number of Positive Definite Matrices [PDF]
Journal of Inequalities and Applications, 2010 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Türkmen, Ramazan, Ulukök, Zübeyde
openaire +5 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source