Results 71 to 80 of about 41,990 (343)

INFLUENCIA DE LA TOPOLOGIA EN EL CONDICIONAMIENTO DE MATRICES DE REDES ELÉCTRICAS TOPOLOGIC INFLUENCE ON THE CONDITIONING OF MATRICES OF ELECTRIC NETWORKS

open access: yesIngeniare: Revista Chilena de Ingeniería, 2008
Se estudia la influencia de la topología de redes eléctricas y alimentadores en el condicionamiento de las matrices asociadas a su modelado matemático. Se observa que el número de condición de estas matrices tiene una gran dependencia de la estructura de
Miguel Arias Albornoz   +2 more
doaj  

Nonlinear Shrinkage Estimation of Large-Dimensional Covariance Matrices [PDF]

open access: yes, 2012
Many statistical applications require an estimate of a covariance matrix and/or its inverse. When the matrix dimension is large compared to the sample size, which happens frequently, the sample covariance matrix is known to perform poorly and may suffer ...
Olivier Ledoit, Michael Wolf
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1494-1512, June 2026.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1473-1493, June 2026.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Potentiometric Determination of Chlorpromazine HCl Using Carbon Paste Electrode in Pure and Pharmaceutical Preparations

open access: yesInternational Journal of Electrochemical Science, 2012
Carbon paste electrode has been developed for the potentiometric determination of chlorpromazine HCl drug. This work has focused on the fabrication of carbon paste ion selective electrode for determination of the drug under investigation using ...
Eman Y.Z. Frag   +4 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Distributed Nash Equilibrium Seeking for Aggregative Games With Linear Convergence Over Digraphs

open access: yesIEEE Access
Aggregative games over directed networks are considered in this paper, where each player aims to minimize its cost function related to its own decision variables and the aggregate of all the players’ decision variables.
Qingyue Wu
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

A Python-Based Pipeline for Preprocessing LC–MS Data for Untargeted Metabolomics Workflows

open access: yesMetabolites, 2020
Preprocessing data in a reproducible and robust way is one of the current challenges in untargeted metabolomics workflows. Data curation in liquid chromatography–mass spectrometry (LC–MS) involves the removal of biologically non-relevant features ...
Gabriel Riquelme   +4 more
doaj   +1 more source

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