Results 11 to 20 of about 1,368,972 (211)

Burst Beliefs – Methodological Problems in the Balloon Analogue Risk Task and Implications for Its Use

open access: yesJournal of Trial and Error, 2020
Alcohol and its effects on aggression have been the subject of many discussions and research papers. Despite this fact, there is still a debate surrounding what it is exactly about alcohol that causes aggression. The current study sought to replicate the
Kristel De Groot
doaj   +1 more source

Administrative data in pediatric critical care research—Potential, challenges, and future directions

open access: yesFrontiers in Pediatrics, 2022
Heterogenous patient populations with small case numbers constitute a relevant barrier to research in pediatric critical care. Prospective studies bring along logistic barriers and—if interventional—ethical concerns.
Nora Bruns   +7 more
doaj   +1 more source

Bayesian nonparametric models for spatially indexed data of mixed type [PDF]

open access: yes, 2014
We develop Bayesian nonparametric models for spatially indexed data of mixed type. Our work is motivated by challenges that occur in environmental epidemiology, where the usual presence of several confounding variables that exhibit complex interactions ...
Best, Nicky   +2 more
core   +2 more sources

Study Designs and Statistical Analyses for Biomarker Research

open access: yesSensors, 2012
Biomarkers are becoming increasingly important for streamlining drug discovery and development. In addition, biomarkers are widely expected to be used as a tool for disease diagnosis, personalized medication, and surrogate endpoints in clinical research.
Yasunori Sato   +2 more
doaj   +1 more source

Levels of Evidence, Quality Assessment, and Risk of Bias: Evaluating the Internal Validity of Primary Research

open access: yesFrontiers in Veterinary Science, 2022
Clinical decisions in human and veterinary medicine should be based on the best available evidence. The results of primary research are an important component of that evidence base.
Jan M. Sargeant   +2 more
doaj   +1 more source

Need for and practical interpretations of the person-year construct in neuropsychiatric research

open access: yesIndian Journal of Psychological Medicine, 2019
In observational studies, groups of interest may be carved out of predictors of interest. Thus, for example, if cardiovascular (CVS) health at age 50 years is the predictor of interest for dementia as the long-term outcome, groups of interest could ...
Chittaranjan Andrade
doaj   +1 more source

Why do so many trials of vitamin D supplementation fail?

open access: yesEndocrine Connections, 2020
Our knowledge of vitamin D has come a long way since the 100 years it took for doctors to accept, between 1860 and 1890, that both sunlight and cod liver oil (a well-known folk remedy) cured and prevented rickets. Vitamins D2/D3 were discovered exactly a
Barbara J Boucher
doaj   +1 more source

Confounding and Confounding Control

open access: yes, 2022
AbstractCurrently, the classical, counterfactual, and structural confounding definitions, are simultaneously used in teaching or practice context of epidemiology. Despite the resemblance, the three definitions are different in many aspects. A unified theory of confounding and confounding control has not been established.
Shaolong Ren, Genming Zhao
openaire   +1 more source

Exchangeability of Measures of Association Before and After Exposure Status Is Flipped: Its Relationship With Confounding in the Counterfactual Model

open access: yesJournal of Epidemiology, 2023
Background: The counterfactual definition of confounding is often explained in the context of exchangeability between the exposed and unexposed groups.
Etsuji Suzuki   +2 more
doaj   +1 more source

The Deductive Approach to Causal Inference

open access: yesJournal of Causal Inference, 2014
This paper reviews concepts, principles, and tools that have led to a coherent mathematical theory that unifies the graphical, structural, and potential outcome approaches to causal inference. The theory provides solutions to a number of pending problems
Pearl Judea
doaj   +1 more source

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