Results 61 to 70 of about 166,452 (368)

Effects of pH and Concentrations of Linoleic and Linolenic Acids on Extent and Intermediates of Ruminal Biohydrogenation in Vitro [PDF]

, 2003
Three experiments were conducted by in vitro incubations in ruminal fluid to investigate the effects of pH and amounts of linoleic and linolenic acids on the extent of their biohydrogenation, the proportions of conjugated linoleic acid (CLA) and trans ...
Bayourthe, Corine, Enjalbert, Francis, Moncoulon, R., Nicot, Marie-Claude, Troegeler-Meynadier, Annabelle   +4 more
core   +2 more sources

Amphiregulin and Epiregulin Confer Radioresistance in Esophageal Squamous Cell Carcinoma Through Oxidative Phosphorylation

Advanced Science, EarlyView.
Oxidative phosphorylation (OXPHOS) activity serves as a critical metabolic determinant of radiotherapy outcomes in esophageal squamous cell carcinoma (ESCC). The CEBPB/AREG/EREG axis drives radioresistance in ESCC by reprogramming OXPHOS. AREG and EREG function as predictive biomarkers for nCRT response and prognosis of ESCC patients.
Zhang Lin, Meilian Yao, Xin Xu, Dong Zhang, Lei Xu, Ling Rong, Xiaohang Wang, Yi Duan, Chengkun Chen, Jun Gu, Yao Zhang, Qiang Liu, Qing Ye, Gaoping Cui, Yujun Hao, Xiumei Ma   +15 more
wiley   +1 more source

Conjugated Linoleic Acid Impairs Endothelial Function [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2006
Objectives— To determine the effect of dietary supplementation with conjugated linoleic acid (CLA) on body mass index (BMI), body fat distribution, endothelial function, and markers of cardiovascular risk.
Taylor, Justin S W, Williams, Simon R P, Rhys, Rhian, James, Phillip, Frenneaux, Michael P   +4 more
openaire   +3 more sources

Neutrophil Extracellular Trap Reprograms Cancer Metabolism to Form a Metastatic Niche Promoting Non‐Small Cell Lung Cancer Brain Metastasis

Advanced Science, EarlyView.
This study mainly combines spatial/single‐cell transcriptomics and metabolomics to reveal LOX+ Malig‐5 as NSCLC brain metastasis‐initiating cells, forming a niche with NET‐releasing neutrophils via the NET‐KRT10 axis. The metastatic niche is involved with metabolic reprogramming, with palmitic acid serving as a key metabolite.
Bo Chen, Karrie M. Kiang, Fangkun Liu, Chuntao Li, Xizhe Li, Chen Weiwei, Xin Fu, Gelei Xiao, Jingyi Sun, Erhan Da, Junbo Liao, Hongshu Zhou, Li Meng, Li Zhou, Tao Song, Longbo Zhang, Gilberto Ka‐Kit Leung, Liyang Zhang   +17 more
wiley   +1 more source

Targeting the Notch1‐YY1‐ICAM1 Signaling Axis Enhances the Efficacy of Immunotherapy in HCC by Activating CD8+ T‐Cell‐Driven Cancer Cell Pyroptosis

Advanced Science, EarlyView.
In hepatocellular carcinoma (HCC), aberrantly activated Notch1 signaling induces its target gene YY1, which impairs immunotherapy efficacy by suppressing tumor cell‐ICAM1‐driven T cell activation and the mediated pyroptosis of T cells against tumor cells.
Ke Zhu, Fa‐Peng Zhang, Chao Qin, Zhi‐Xiao Song, Cai‐Ni Yang, Shu‐Sheng Lin, Xian‐Huan Yu, Wen‐Rui Wu, Chao‐Qun Liu, Chao Liu, Lei‐Bo Xu   +10 more
wiley   +1 more source

Effets des acides gras conjugués sur les composantes de la dépense énergétique chez la souris et le hamster

Oléagineux, Corps gras, Lipides, 2005
We measured the effects of feeding conjugated linoleic acids (CLA) on the various components of energy expenditure in two species known to react differently to CLA treatments, the hamster and the mouse.
Even Patrick, Bouthegourd Jean-Christophe, Martin Jean-Charles, Quignard Boulangé Annie   +3 more
doaj   +1 more source

Trans fatty acids and conjugated linoleic acid in the buffalo milk

Italian Journal of Animal Science, 2010
The fatty acid content in milk samples, obtained from buffaloes of the Bulgarian Murrah breed reared in a buffalo farm in the Agricultural Institute - Shumen was investigated. Milk samples were obtained from the morning and evening milking.
T. Peeva, G. Mihaylova
doaj   +1 more source

The g.4290 C>G Polymorphism in the FADS2 Gene Modifies the Fatty Acid Profile of the Pectoralis Superficialis Muscle of Ross 308 Broiler Chickens

Animals, 2022
The effect of the g.4290 C>G substitution in the FADS2 gene and g.285 C>T in the FABP4 gene on carcass quality, meat quality, and fatty acid profile of the pectoralis superficialis muscle of 238 male broiler chickens reared up to 45 days of age was ...
Urszula Kaczor, Sebastian Sawicki, Joanna Nowak, Julia Gabryś, Jakub Jurczyk, Dorota Wojtysiak, Katarzyna Połtowicz   +6 more
doaj   +1 more source

Conjugated linoleic acid (CLA) and obesity [PDF]

Public Health Nutrition, 2007
AbstractBackgroundThe term conjugated linoleic acid (CLA) refers to several positional and geometric conjugated dienoic isomers of linoleic acid (LA), of which the trans-10,cis-12 isomer has been reported to reduce adiposity and increase lean mass in mice and other animals when included at ≤1% of the diet.
Manuela-Belén, Silveira, Raffaele, Carraro, Susana, Monereo, Javier, Tébar   +3 more
openaire   +2 more sources

Isomers of conjugated linoleic acids are synthesized via different mechanisms in ruminal digesta and bacteria Published, JLR Papers in Press, July 20, 2007.

Journal of Lipid Research, 2007
Digesta samples from the ovine rumen and pure ruminal bacteria were incubated with linoleic acid (LA) in deuterium oxide-containing buffer to investigate the mechanisms of the formation of conjugated linoleic acids (CLAs).
R. Wallace, N. Mckain, K. Shingfield, E. Devillard   +3 more
semanticscholar   +1 more source