Results 61 to 70 of about 985,503 (290)

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu   +10 more
wiley   +1 more source

CLAs, nature, origin and some metabolic aspects

open access: yesOléagineux, Corps gras, Lipides, 2005
CLA (conjugated linoleic acid) is a generic term for several isomers of linoleic acid with conjugated double bonds. They have been reported since 1935 in butter fat, but the major natural isomer (9cis,11trans-18 :2) was identified in 1977 and further ...
Chardigny Jean-Michel   +2 more
doaj   +1 more source

Fatty acid profile in the ruminal fluid and in the m. longissimus dorsi of lambs fed herbage or concentrate with or without tannins

open access: yesItalian Journal of Animal Science, 2010
Twenty-eight male lambs were divided into two groups at age 45 d. Fourteen lambs were given fresh herbage (vetch); the remaining lambs were fed a concentrate-based diet.
Alessandro Priolo   +6 more
doaj   +1 more source

Enhancing the nutritional and health value of beef lipids and their relationship with meat quality [PDF]

open access: yes, 2014
This paper focusses on dietary approaches to control intramuscular fat deposition to increase beneficial omega-3 polyunsaturated fatty acids (PUFA) and conjugated linoleic acid content, and reduce saturated fatty acids in beef.
Scollan, Nigel D.   +11 more
core   +1 more source

Immunomodulatory properties of conjugated linoleic acid [PDF]

open access: yesThe American Journal of Clinical Nutrition, 2004
In vitro studies of the use of immune cells and animal models demonstrate that conjugated linoleic acid (CLA), a lipid, modulates immune function. In addition, recent publications demonstrate that 2 active CLA isomers (ie, cis-9,trans-11 CLA and trans-10,cis-12 CLA) modulate immune function in humans.
Marianne, O'Shea   +2 more
openaire   +2 more sources

Modified Titanium Dental Implants: The Current Progress of Soft‐Tissue Integration Methods

open access: yesAdvanced NanoBiomed Research, EarlyView.
Dental implants are an established solution for tooth loss, yet achieving soft tissue integration (STI) around the transmucosal region remains a challenge. The natural tooth–gingiva interface is poorly replicated on titanium implants. This review explores surface modification strategies, ranging from surface chemistry and topography to biological ...
Daniel De Maria   +5 more
wiley   +1 more source

CONJUGATED LINOLEIC ACID, FATTY ACID PROFILE AND PROCESS PROPERTIES IN KUMIS - FERMENTED MILK CONSUMED IN COLOMBIA

open access: yesVitae, 2011
In this study, we reported the concentration of conjugated linoleic acid of the main commercial kumis consumed and distributed in Colombia, as well as the concentration of conjugated linoleic acid of an artisanal kumis elaborated with two different types
Julián A. OSORIO   +3 more
doaj  

Role of the protozoan Isotricha prostoma, liquid-, and solid-associated bacteria in rumen biohydrogenation of linoleic acid

open access: yesAnimal, 2009
From the simultaneous accumulation of hydrogenation intermediates and the disappearance of Isotricha prostoma after algae supplementation, we suggested a role of this ciliate and/or its associated bacteria in rumen biohydrogenation of unsaturated fatty ...
C. Boeckaert   +5 more
doaj   +1 more source

The g.4290 C>G Polymorphism in the FADS2 Gene Modifies the Fatty Acid Profile of the Pectoralis Superficialis Muscle of Ross 308 Broiler Chickens

open access: yesAnimals, 2022
The effect of the g.4290 C>G substitution in the FADS2 gene and g.285 C>T in the FABP4 gene on carcass quality, meat quality, and fatty acid profile of the pectoralis superficialis muscle of 238 male broiler chickens reared up to 45 days of age was ...
Urszula Kaczor   +6 more
doaj   +1 more source

Conjugated Linoleic Acid Isomers and Cancer , [PDF]

open access: yesThe Journal of Nutrition, 2007
We reviewed the literature regarding the effects of conjugated linoleic acid (CLA) preparations enriched in specific isomers, cis9, trans11-CLA (c9, t11-CLA) or trans10, cis12-CLA (t10, c12-CLA), on tumorigenesis in vivo and growth of tumor cell lines in vitro.
Nirvair S, Kelley   +2 more
openaire   +2 more sources

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