Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou +14 more
wiley +1 more source
Performance Analysis of Non-Orthogonal Multiple Access-Enhanced Autonomous Aerial Vehicle-Assisted Internet of Vehicles over Rician Fading Channels. [PDF]
Zhang Z +7 more
europepmc +1 more source
Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang +22 more
wiley +1 more source
Unveiling public perceptions of battery technology in autonomous vehicles via topic modeling of news articles. [PDF]
Kang I, Yang J, Kim Z.
europepmc +1 more source
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang +18 more
wiley +1 more source
End-to-End Teleoperated Driving Video Transmission Under 6G with AI and Blockchain. [PDF]
Frontelo IB +3 more
europepmc +1 more source
p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa +23 more
wiley +1 more source
Adaptive Fusion of LiDAR Features for 3D Object Detection in Autonomous Driving. [PDF]
Wang M, Li D, Casas JR, Ruiz-Hidalgo J.
europepmc +1 more source
Cooperative Intelligent Transport Systems: The Impact of C-V2X Communication Technologies on Road Safety and Traffic Efficiency. [PDF]
Wang J +4 more
europepmc +1 more source

