Results 71 to 80 of about 355,537 (249)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Fibrosis-Associated Signaling Molecules Are Differentially Expressed in Palmar Connective Tissues of Patients with Carpal Tunnel Syndrome and Dupuytren’s Disease [PDF]

, 2022
Ivo Tripković, Marin Ogorevc, Dubravka Vuković, Mirna Saraga‐Babić, Snježana Mardešić   +4 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Abstracts of Papers Presented at the Connective Tissue Oncology Society 4th Annual Scientific Meeting, 12–14 November 1998, Vancouver, BC, Canada [PDF]

, 1999
Brian Sullivan, Olin Ooper, Robert M. Bell, Canada Benjam, Sybil Bierm, Uri Bram, Canada Lee, Howard C. Elman, Urazgil'deeva Sa, Jonathan J. Lewis, Robert Arcus, U Sa O Le N Ielsen, D Enm, U Panicek, Piero Sa, Italy Picci, Ira J. Spiro, Usa Rits Van Coevorden, Jaap Verweij, Sharon M. Weiss, J Verw Eij, Ian Judson, Michael H. Lee, W Uka, Javier Buesa, R Colem, Eleonora Di Paola, D. Locci-Tonelli, M Van G Labbeke, Thomas Tursz, P Ijhuis, Michael Schaapveld, R. Otter, H Oekstra, S Ing Le Institu Tion, S. Tu, Dy Cassoni, J Helan, M Dr, G Ene Exp Ressio N A, M Lticenter, Stu Dy, Jay S. Wunder, I Ndr, Aileen M. Davis, Shelley B. Bull, C Beaucham, E U Conrad, R Gr Imer, Jonathan Ealey, Michael G. Rock, M Rock   +51 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

SIGNIFICANCE OF CONNECTIVE TISSUE DYSPLASIA FORSECONDARY PYELONEPHRITIS IN CHILDREN IN PUBERTY [PDF]

, 2020
О. В. Сидорович, В. И. Горемыкин, S.Yu. Elizarova, I.A. Glushakov, V. D. Morozova   +4 more
openalex   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Musculoskeletal involvement in systemic sclerosis

Rheumatology
Systemic sclerosis (SSc) is a multi-organ, systemic connective tissue disease, which affects the lungs, heart, gastrointestinal tract, kidneys, skin, and musculoskeletal system.
Ewa Wielosz, Marcin Grzegorz Hyła
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source