Results 71 to 80 of about 320,293 (286)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

A histopathologic evaluation of gross lesions excised from commercially important North Altantic marine fishes [PDF]

, 1986
Histopathologic studies of lesions found in commercially important North Atlantic marine fishes are uncommon. As part of a comprehensive Northeast Fisheries Center program ("Ocean Pulse") to evaluate environmental and resource health on the U.S ...
Despres-Patanjo, Linda, Murchelano, Robert A., Ziskowski, John   +2 more
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Serum YKL-40 levels and disease characteristics in patients with rheumatoid arthritis

Caspian Journal of Internal Medicine, 2019
Background: The present study aimed to evaluate serum YKL-40 levels in patients with rheumatoid arthritis (RA) compared to healthy subjects and to search whether there is an association between YKL-40 levels and disease characteristics in RA. Methods: In
Mohammad Reza Jafari-Nakhjavani, Amir Ghorbanihaghjo, Babak Bagherzadeh-Nobari, Aida Malek-Mahdavi, Nadereh Rashtchizadeh   +4 more
doaj  

IL-1β Inhibits Human Osteoblast Migration

Molecular Medicine, 2013
Bone has a high capacity for self-renewal and repair. Prolonged local secretion of interleukin 1β (IL-1β), however, is known to be associated with severe bone loss and delayed fracture healing.
Nina-Emily Hengartner, Jörg Fiedler, Anita Ignatius, Rolf E. Brenner   +3 more
doaj   +1 more source

Prevalence of smoking among the students resided at dormitories in Golestan university of medical sciences, Iran [PDF]

, 2014
Introduction: Cigarette smoking leads to harmful physical and emotional problems and also is a predisposed factor for the addiction. The aim of this study was an attempt to determine the rate of prevalence and causes of smoking among the students of ...
Aghaie, M., Bamyar, R., Jouybari, L., Mohebi, R., Qhorbani, M., Sanagoo, A., Shojaa, M.   +6 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Distribution of HLA-DRB1 Alleles in Patients With Antiphospholipid Syndrome and Their Association With Antiphospholipid Antibodies Presence and Damage Indexes

Journal of Immunology Research
Antiphospholipid syndrome (APS) is frequently coexisting with systemic lupus erythematosus (SLE) and the knowledge on its genetic background is essential. The objective of this work was to assess distribution of human leukocyte antigen (HLA)-DRB1 alleles
Ewa Haladyj, Barbara Stypinska, Agata Matusiewicz, Marzena Olesinska, Agnieszka Paradowska-Gorycka   +4 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

High Prevalence of Cold Intolerance in Rheumatoid Arthritis: A Case–Control Study

Clinical Case Reports
Cold intolerance is more common in rheumatoid arthritis patients than control. Cold intolerance tends to develop after rheumatoid arthritis onset and is associated with longer disease duration, with pain and swelling being dominant features.
Mohsen Soroush, Rojin Farzaneh, Elaheh Babapour, Amirreza Jabbaripour Sarmadian, Sami Rassouli, Golrokh Hassanzadeh Behrouz, Amirreza Naseri, Maryam Mahmoudi, Kamal Esalatmanesh, Aida Malek Mahdavi, Alireza Khabbazi   +10 more
doaj   +1 more source