Results 111 to 120 of about 26,063 (225)

Increased expression of connexins 26 and 43 in lymph node metastases of breast cancer [PDF]

, 2006
Mariusz Koda, S Sułkowski, A Lenczewski, Mariusz Koda, Andrzej Wincewicz, M Baltaziak, M Sulkowska   +6 more
openalex   +1 more source

LKB1–AMPK Signaling Pathway in Cardiovascular and Other Diseases

MedComm, Volume 7, Issue 3, March 2026.
The LKB1–AMPK pathway has a central regulatory role in various diseases. Dysfunction of this pathway can lead to pathological processes in cardiovascular diseases (atrial fibrillation, myocardial infarction, myocardial hypertrophy, atherosclerosis), metabolic diseases (diabetes and kidney disease), neurodegenerative diseases (Alzheimer's disease ...
Zhuo Chen, Qin Yang, Guo‐Wei He
wiley   +1 more source

Gap junction protein connexin-43 interacts directly with microtubules [PDF]

, 2001
Ben N. G. Giepmans, Ingrid Verlaan, Trudi Hengeveld, Hans Janssen, Jero Calafat, Matthias M. Falk, Wouter H. Moolenaar   +6 more
openalex   +1 more source

Peroxisome Proliferator‑Activated Receptor Gamma Coactivator‑1α Deficiency in Hippocampal Astrocytes Underlies Enhanced Fear Memory Retrieval in Male Posttraumatic Stress Disorder Model Mice

MedComm, Volume 7, Issue 3, March 2026.
PGC‑1α downregulation in hippocampal astrocytes disrupts ATP release and reduces connexin 43 (CX43) expression, impairing neuro‑glial communication. This promotes enhanced fear memory retrieval in PTSD. Chemogenetic activation of astrocytes or PGC‑1α agonist treatment rescues both CX43 expression and fear behavior, identifying astrocytic PGC‑1α/CX43 as
Juan Wang, Xiaoyu Chen, Daokang Chen, Shaojie Yang, Jingji Wang, Ming Chen, Guoqi Zhu   +6 more
wiley   +1 more source

Chlorpromazine overcomes temozolomide resistance in glioblastoma by inhibiting Cx43 and essential DNA repair pathways

Journal of Translational Medicine
Background In the fight against GBM, drug repurposing emerges as a viable and time-saving approach to explore new treatment options. Chlorpromazine, an old antipsychotic medication, has recently arisen as a promising candidate for repositioning in GBM ...
Paola Matarrese, Michele Signore, Barbara Ascione, Giulia Fanelli, Marco G. Paggi, Claudia Abbruzzese   +5 more
doaj   +1 more source

Roles of astrocytic connexin-43, hemichannels, and gap junctions in oxygen-glucose deprivation/reperfusion injury induced neuroinflammation and the possible regulatory mechanisms of salvianolic acid B and carbenoxolone [PDF]

, 2018
Xiang Yin, Liangshu Feng, Di Ma, Ping Yin, Xinyu Wang, Shuai Hou, Yulei Hao, Jingdian Zhang, Meiying Xin, Jiachun Feng   +9 more
openalex   +1 more source

Synthetic Cells on Demand: From Molecular Stimuli to Cellular Functions

ChemSystemsChem, Volume 8, Issue 2, March 2026.
ABSTRACT Synthetic cells constructed via bottom‐up approaches using lipid or polymer vesicles have become essential tools for mimicking cellular functions and studying synthetic biological systems. These vesicles can undergo morphological changes and trigger internal reactions in response to external stimuli, such as osmotic pressure, temperature, pH ...
Masato Suzuki, Koki Kamiya
wiley   +1 more source

Fluorescence Guided Raman Spectroscopy enables the training of robust support vector machines for the detection of tumour marker proteins

Scientific Reports
Raman spectroscopy provides comprehensive biochemical information on a sample’s composition, yet it is often used to analyze aggregated spectra rather than specific shifts.
Johannes Reifenrath, Benjamin Gardner, Alexander Gigler, Friederike Liesche-Starnecker, Suzy Eldershaw, Nick Stone, Jürgen Schlegel   +6 more
doaj   +1 more source

Pathological remodeling of cardiac gap junction connexin 43—With special reference to arrhythmogenesis

, 2009
Issei Imanaga
openalex   +1 more source

Artificial lipidation of proteins and peptides: from mechanism to clinical applications

The FEBS Journal, Volume 293, Issue 5, Page 1269-1284, March 2026.
Artificial lipidation transforms protein and peptide therapeutics by attaching fatty acid chains through reversible or permanent chemical strategies. This biomimetic approach delivers four key therapeutic advantages: extended circulation times (enabling weekly instead of daily dosing), alternative administration routes including oral delivery, precise ...
Jiaming Mu, Emily Vong, Sheiliza Carmali
wiley   +1 more source