Results 211 to 220 of about 26,063 (225)
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Role of connexin 43 in cardiovascular diseases
European Journal of Pharmacology, 2015Gap junctions (GJs) channels provide the basis for intercellular communication in the cardiovascular system for maintenance of the normal cardiac rhythm, regulation of vascular tone and endothelial function as well as metabolic interchange between the cells. They allow the transfer of small molecules and may enable slow calcium wave spreading, transfer
PECORARO, MICHELA +3 more
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Redistribution of connexin 43 during cell division
Cell Biology International, 2016AbstractGap junction channels, once clustered into gap junction plaques, allow communication of essential metabolites between cells. Gap junction plaques have been reported to be lost from the cell surface during cell division. The mechanism involved in this loss of gap junction plaques during mitosis is unclear, but we hypothesize that an ...
Oluseyi A, Vanderpuye +2 more
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Posttranscriptional regulation of connexin-43 expression
Archives of Biochemistry and Biophysics, 2012Posttranscriptional regulation of the biosynthesis of connexins, the building blocks of gap junctional channels, may occur by modulation of connexin mRNA stability and translation. To date, few RNA binding proteins and micro-RNAs (miRNAs) affecting connexin expression are known.
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Mature olfactory receptor neurons express connexin 43
The Journal of Comparative Neurology, 2000The expression of the gap junction subunit connexin 43 was studied in the olfactory epithelium of adult mice. In agreement with conclusions from previous immunohistochemical studies, we observed expression of mRNA encoding for connexin 43 in layers of the epithelium containing nuclei belonging to sustentacular cells.
C, Zhang, T E, Finger, D, Restrepo
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Clinical Science, 2003
The present paper analyses the results of competitive blood-cell repopulation experiments in which Cx43-WT (connexin 43 wild-type) host mice, whose own HSCs (haemopoietic stem cells) were deleted, were grafted with fetal liver cells: 50% Gpi-1a (glucose phosphate isomerase-1a)/Cx43-WT cells competing with 50% Gpi-1b/Cx43-WT, 50% Gpi-1b/Cx43-HZ ...
Martin, Rosendaal, Mervyn, Stone
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The present paper analyses the results of competitive blood-cell repopulation experiments in which Cx43-WT (connexin 43 wild-type) host mice, whose own HSCs (haemopoietic stem cells) were deleted, were grafted with fetal liver cells: 50% Gpi-1a (glucose phosphate isomerase-1a)/Cx43-WT cells competing with 50% Gpi-1b/Cx43-WT, 50% Gpi-1b/Cx43-HZ ...
Martin, Rosendaal, Mervyn, Stone
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Connexin 43 expression in normal versus dysfunctional labor
American Journal of Obstetrics and Gynecology, 2002We sought to determine whether connexin 43 (Cx43), the major myometrial gap junction protein, is differentially expressed in normal versus dysfunctional labor.Myometrial biopsies were obtained from 28 patients undergoing cesarean section and grouped into the following categories: (1) no labor, (2) dysfunctional labor, and (3) normal labor. Northern and
Brian T, Pierce +4 more
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Connexin 43 ontogeny in fetal sheep adrenal glands
Steroids, 2003We examined fetal sheep adrenal glands from 99 to 130 days of gestational age (dGA) to see how connexin 43 (Cx43), the major if not the only adult adrenal gap junction protein, changes expression as the adrenal cortex emerges from the well-documented refractory period to participate in labor and delivery.
T J, McDonald +3 more
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Connexin 43 is localized with actin in tenocytes
Cell Motility, 2006AbstractVarieties of cell–matrix or cell–cell adhesions are associated with the actin cytoskeleton. However, for gap junctions, which are both channels and adhesions, there has been little evidence for such an association. The purpose of this study was to determine if connexin 43 (Cx43) associates with actin and to determine if this association is ...
Michelle E, Wall +3 more
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Connexin 43 mediates PFOS-induced apoptosis in astrocytes
Chemosphere, 2015Perfluorooctane sulfonate (PFOS) is a man-made environmental pollutant that is toxic to mammals. However, the neurotoxic effects of PFOS remain largely unexplored. In this study, we determined the role of an astrocyte specific gap junction protein, connexin 43 (Cx43), in PFOS-induced apoptosis.
Li, Dong +6 more
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Mitochondrial connexin 43 hemichannels
Journal of Molecular and Cellular Cardiology, 2007Elisabet Miro-Casas +10 more
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