Results 151 to 160 of about 1,550 (182)

Expression of connexin36 mRNA in adult rodent brain

NeuroReport, 2000
A new member of the connexin gene family, named Connexin36 (Cx36) has, recently, been identified in rodents and shown to be preferentially, if not exclusively, expressed in neurones of the adult CNS. In this study we present a detailed in situ hybridization analysis of the expression pattern of mouse Connexin 36 (mCx36) mRNA in the adult mouse brain ...
PARENTI, Rosalba, GULISANO, Massimo, ZAPPALA', AGATA, CICIRATA F.   +3 more
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Direct association of connexin36 with zonula occludens-2 and zonula occludens-3 [PDF]

Neurochemistry International, 2009
The gap junction protein connexin36 (Cx36) is widely expressed in neurons and was previously shown to interact with the PDZ domain-containing protein zonula occludens-1 (ZO-1). We investigated whether Cx36 is also able to interact with other members of zonula occludens family of proteins, namely, ZO-2 and ZO-3, the former of which was reported to be co-
Xinbo Li, James Imre Nagy
exaly   +3 more sources

Developmental changes in the expression level of connexin36 in the rat retina

Cell and Tissue Research, 2014
Connexin36 (Cx36) is the major gap junction forming protein in the brain and the retina; thus, alterations in its expression indicate changes in the corresponding circuitry. Many structural changes occur in the early postnatal retina before functional neuronal circuits are finalized, including those that incorporate gap junctions.
Kovács-Öller, Tamás, Raics, K., Orbán, József, Nyitrai, Miklós, Völgyi, Béla   +4 more
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Characterization of connexin36 gap junctions in the human outer retina

Brain Structure and Function, 2015
Retinal connexins (Cx) form gap junctions (GJ) in key circuits that transmit average or synchronize signals. Expression of Cx36, -45, -50 and -57 have been described in many species but there is still a disconcerting paucity of information regarding the Cx makeup of human retinal GJs. We used well-preserved human postmortem samples to characterize Cx36
Orsolya, Kántor, Zsigmond, Benkő, Anna, Énzsöly, Csaba, Dávid, Angela, Naumann, Roland, Nitschke, Arnold, Szabó, Emese, Pálfi, József, Orbán, Miklós, Nyitrai, János, Németh, Ágoston, Szél, Ákos, Lukáts, Béla, Völgyi   +13 more
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Altered olivocerebellar activity patterns in the connexin36 knockout mouse

The Cerebellum, 2007
The inferior olive (IO) has among the highest densities of neuronal gap junctions in the nervous system. These gap junctions are proposed to be the underlying mechanism for generating synchronous Purkinje cell complex spike (CS) activity. Gap junctions between neurons are formed mostly by connexin36 proteins.
Sarah P, Marshall, Ruben S, van der Giessen, Chris I, de Zeeuw, Eric J, Lang   +3 more
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Genomic organization and chromosomal localization of the mouse Connexin36 (mCx36) gene

Gene, 2000
Connexin36 (Cx36) is a new connexin that was recently cloned in mouse, rat and human. It is highly expressed in neurons of the CNS. To gain insight into the transcriptional regulation of this gene, we have cloned the genomic region containing the entire mCx36 gene and sequenced about 7.6kb around the coding region.
CICIRATA F, PARENTI R, SPINELLA F, GIGLIO, SABRINA RITA, TUORTO F, ZUFFARDI O, GULISANO M.   +6 more
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Connexin36 Is Essential for Transmission of Rod-Mediated Visual Signals in the Mammalian Retina [PDF]

Neuron, 2002
To examine the functions of electrical synapses in the transmission of signals from rod photoreceptors to ganglion cells, we generated connexin36 knockout mice. Reporter expression indicated that connexin36 was present in multiple retinal neurons including rod photoreceptors, cone bipolar cells, and AII amacrine cells. Disruption of electrical synapses
Michael R Deans, Bela Volgyi, David L Paul   +2 more
exaly   +3 more sources

EXPRESSION OF GAP JUNCTION CONNEXIN36 IN ADULT RAT RETINAL GANGLION CELLS

Journal of Integrative Neuroscience, 2002
Electrophysiological and ultrastructural studies have demonstrated that gap junctions connect diverse types of neurons in the central nervous system, permitting direct electrical and metabolic coupling. A member of gap junction channel subunit connexin36 (Cx36), is probed for the location of cell-to-cell communication in the mammalian retina, where gap
Soh, Hidaka, Toshiaki, Kato, Ei-Ichi, Miyachi   +2 more
exaly   +3 more sources

Loss of connexin36 increases retinal cell vulnerability to secondary cell loss

European Journal of Neuroscience, 2005
AbstractAccruing evidence indicates that gap junctions are involved in neuronal survival after brain injury. The present study was aimed at clarifying the contribution of the neuronal gap‐junction protein connexin36 (Cx36) to secondary cell loss after injury in the mouse retina.
Katharine, Striedinger, Elisabeth, Petrasch-Parwez, Georg, Zoidl, Markus, Napirei, Carola, Meier, Ulf T, Eysel, Rolf, Dermietzel   +6 more
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Elevated auditory brainstem response thresholds in mice with Connexin36 gene ablation

Acta Oto-Laryngologica, 2015
Expression of connexin36 (Cx36) and electrical synapses formed by Cx36-containing gap junctions contribute to normal auditory brainstem response thresholds in mice.Electrical synaptic transmission mediated by gap junctions has not been intensively studied in the auditory system.
Brian W, Blakley, Carlos E A, Garcia, Suzete R, da Sliva, Victor M B, Florêncio, James I, Nagy   +4 more
openaire   +2 more sources