Results 181 to 190 of about 42,495 (277)

Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications

Pharmacological Reviews, 2017
L. Leybaert, P. Lampe, S. Dhein, B. Kwak, P. Ferdinandy, E. Beyer, D. Laird, C. Naus, C. Green, R. Schulz   +9 more
semanticscholar   +1 more source

Blockade of P2X7 receptors preserves blood retinal barrier integrity by modulating the plasmalemma vesicle‐associated protein: Implications for diabetic retinopathy

British Journal of Pharmacology, Volume 182, Issue 12, Page 2603-2620, June 2025.
Background and Purpose Plasmalemma vesicle‐associated protein (PLVAP) regulates transcytosis in vascular endothelial cells. PLVAP expression is increased in pathological conditions, such as diabetic retinopathy. P2X7 receptor antagonists have been shown to preserve blood‐retinal barrier (BRB) integrity.
Chiara Bianca Maria Platania, Francesca Lazzara, Kenneth Mitton, Naomi Haque, Wendelin Dailey, Federica Conti, Erika Giuffrida, Filippo Drago, Anca Hermenean, Cornel Balta, Hildegard Herman, Alina Ciceu, Maria Consiglia Trotta, Michele D'Amico, Giuseppe Nicosia, Settimio Rossi, Claudio Bucolo   +16 more
wiley   +1 more source

The molecular basis of selective permeability of connexins is complex and includes both size and charge [PDF]

, 2000
Bruce J. Nicholson, Paul A. Weber, Fengli Cao, Hao-Chen Chang, Paul D. Lampe, Gary S. Goldberg   +5 more
openalex   +1 more source

Adiponectin and gastric fundus: A potential target for gut–brain axis dysfunctions

Physiological Reports, Volume 13, Issue 11, June 2025.
Abstract Adiponectin (ADPN) is a pleiotropic hormone produced by adipose tissue involved in the control of body weight, energy expenditure, and feeding behaviors. Alongside a central effect, ADPN acts on peripheral organs such as the stomach, where it can favor gastric fundus relaxation, reinforcing central satiety signals.
R. Garella, F. Palmieri, F. Chellini, L. Tarchi, V. Ricca, G. Castellini, C. Sassoli, R. Squecco   +7 more
wiley   +1 more source

Bone-Resorbing Osteoclasts Contain Gap-Junctional Connexin-43 [PDF]

, 2000
Joanna Ilvesaro, Kalervo Väänänen, Juha Tuukkanen   +2 more
openalex   +1 more source

Histone Deacetylase 6 Controls Atrial Fibrosis and Remodeling in Postinfarction Mice Through the Modulation of Wnt3a/GSK‐3β Signaling

The FASEB Journal, Volume 39, Issue 10, 31 May 2025.
Elevated levels of HDAC6 activate the Wnt3a/GSK3β signaling pathway, leading to the phosphorylation of GSK3β and its subsequent binding to HDAC6, followed by translocation into the mitochondria. Within the mitochondria, GSK3β interacts with TFAM, competitively reducing TFAM's binding to mtDNA. This reduction decreases mtDNA transcription and stability,
Shangzhi Shu, Junqiao Fang, Longguo Zhao, Jiatong Han, Meiping Zhang, Chaoqun Huang, Xian Wu Cheng, Shuyan Li   +7 more
wiley   +1 more source

Connexin 43-Enhanced Suicide Gene Therapy Using Herpesviral Vectors [PDF]

, 2000
Peggy Marconi, Masakazu Tamura, Shusuke Moriuchi, David Krisky, Ajay Niranjan, William F. Goins, Justus B. Cohen, Joseph C. Glorioso   +7 more
openalex   +1 more source

Casein Kinase II Phosphorylates Lens Connexin 45.6 and Is Involved in Its Degradation [PDF]

, 2000
Xinye Yin, Paul T. Jedrzejewski, Jean X. Jiang   +2 more
openalex   +1 more source

Interleukin-1β Increases the Functional Expression of Connexin 43 in Articular Chondrocytes: Evidence for a Ca2+-Dependent Mechanism [PDF]

, 2000
R Tonon, Paola D’Andrea
openalex   +1 more source

Expression of gap junction genes connexin 32, connexin 43 and their proteins in hepatocellular carcinoma and normal liver tissues [PDF]

, 2000
Xiang Da Dong
openalex   +1 more source