CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.This study reveals that USP11 mediates depressive‐like behaviors and mitochondrial dysfunction in the prefrontal cortex. Mechanistically, USP11 directly binds to and deubiquitinates CK2α, thereby stabilizing its protein level and promoting mitochondrial impairment.
Yuqi Feng +14 more
wiley +1 more source
KID Syndrome: Report of a Scandinavian Patient with Connexin‐26 Gene Mutation
, 2004 Anette Bygum +6 more
openalex +1 more source
Roles of astrocytic connexin-43, hemichannels, and gap junctions in oxygen-glucose deprivation/reperfusion injury induced neuroinflammation and the possible regulatory mechanisms of salvianolic acid B and carbenoxolone [PDF]
, 2018 Xiang Yin +9 more
openalex +1 more source
Pancreatic Islet Cell Crosstalk: Insight Into α‐/β‐Cell Compensatory Mechanisms
Comprehensive Physiology, Volume 16, Issue 3, June 2026.α‐cell remodeling compensates for impaired β‐cell function. Intra‐islet glucagon/GLP‐1 signaling is upregulated and becomes essential in prediabetic islets. Flexible receptor engagement reflects functional plasticity in hormonal control of insulin secretion. Created in BioRender. Plecita, L. (2026); https://BioRender.com/pgjjg3m.
Štěpánka Benáková +5 more
wiley +1 more source
Loop Gating of Connexin Hemichannels Involves Movement of Pore-lining Residues in the First Extracellular Loop Domain [PDF]
, 2008 Vytas K. Verselis +4 more
openalex +1 more source
The Supporting Role of Natural Products as Effective Adjuvants in Cancer Immunotherapy
eFood, Volume 7, Issue 3, June 2026.Natural products, as multi‐target and low‐toxicity adjuvants, enhance immune checkpoint inhibitor responses and reduce immune‐related adverse events through T cell reprogramming, microenvironment remodeling, and microbiota‐immune modulation. ABSTRACT Immune checkpoint inhibitors (ICIs) have revolutionized the treatment landscape of malignant tumors ...
Boyang Liu +6 more
wiley +1 more source
Biomaterial Physical Cues as Gene Regulators for Cellular Agriculture
Advanced Genetics, Volume 7, Issue 2, June 2026.This review elucidates how biomaterial physical cues—ranging from matrix stiffness to remote electromagnetic fields—serve as extrinsic regulators of gene expression in cellular agriculture. By identifying central mechanotransduction pathways that bridge physical inputs to genetic remodeling, the authors propose the “Material Genome” concept: a ...
Jianuo Liu, Ye Liu
wiley +1 more source
Connexin-mimetic peptide Gap 27 decreases osteoclastic activity [PDF]
, 2001 Joanna Ilvesaro +2 more
openalex +1 more source
Roles of connexins in atherosclerosis and ischemia-reperfusion injury
, 2012 Connexins are members of a large family of transmembrane proteins that oligomerize to form connexons or hemichannels, and connexons of adjacent cells dock to make gap junction channels.
Morel, Sandrine, Kwak, Brenda
core