Results 171 to 180 of about 38,435 (285)

SORBS2: A Molecular Nexus in Multisystem Diseases Through Scaffold‐Mediated Regulation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Sorbin and SH3 Domain Containing 2 (SORBS2), a multifunctional scaffold protein harbouring Sorbin homology (SoHo) and Src homology 3 (SH3) domains, serves as a molecular hub in human diseases by integrating cytoskeletal remodelling, signal transduction and RNA metabolic regulation. This study systematically analyses SORBS2's molecular features,
Qiwei Jia, Yong Zhang
wiley   +1 more source

Gap junctions in hematopoietic stroma control proliferation and differentiation of blood cell precursors

Anais da Academia Brasileira de Ciências, 2004
We examined gap junction communication in an in vitro model of hematopoiesis, using the murine bone marrow stroma cell line S-17, and primary cultures of murine marrow-derived blood cell precursors.
Bodi Estevão, Hurtado Sandra P., Carvalho Marcelo A., Borojevic Radovan, Carvalho Antônio C. Campos de   +4 more
doaj  

The connexins

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2004
openaire   +2 more sources

Cells and ionic conductances contributing to spontaneous activity in bladder and urethral smooth muscle

The Journal of Physiology, Volume 604, Issue 9, Page 3611-3632, 1 May 2026.
Abstract figure legend Cells and conductances contributing to spontaneous activity in the lower urinary tract. Bladder and urethra exhibit spontaneous contractions at both cellular and tissue levels. Both detrusor and urethral smooth muscle cells display activity that is regular and rhythmic.
Bernard T. Drumm, Neha Gupta, Alexandru Mircea, Caoimhin S. Griffin   +3 more
wiley   +1 more source

Mechanisms of permselectivity of connexin hemichannels to small molecules. [PDF]

J Biol Chem
Lovatt A, Butler J, Dale N.
europepmc   +2 more sources

Genetically engineered cardiac pacemaker: stem cells transfected with HCN2 gene and myocytes - a model

, 2005
Artificial biological pacemakers were developed and tested in canine ventricles. Next steps will require obtaining oscillations sensitive to external regulations, and robust with respect to long term drifts of expression levels of pacemaker currents and ...
Kanani, Sandra, Krinsky, Valentine, Pumir, Alain   +2 more
core  

Connexins

Connexins are tetraspan transmembrane proteins that form gap junctions and facilitate direct intercellular communication, a critical feature for the development, function, and homeostasis of tissues and organs. In addition, a growing number of gap junction-independent functions are being ascribed to these proteins.
Aasen, Trond||, Johnstone, Scott||, Vidal-Brime, Laia, Lynn, K. Sabrina, Koval, Michael||   +4 more
openaire   +1 more source

Gap Junction-Mediated Communication in Melanoma: From Tumor Progression to Treatment Response. [PDF]

Int J Mol Sci
Massoud J, Ibrahim S, Jensen M, Beary MC, Nafchi B, Springer M, Zucker SN.   +6 more
europepmc   +1 more source

Hypoxia Increases Connexin46 and Connexin43 Levels in KNS-42 Glioblastoma Cells. [PDF]

Int J Mol Sci
Minogue PJ, Beyer EC, Berthoud VM.
europepmc   +1 more source

Cerebellar astrocytic alterations in depression. [PDF]

Transl Psychiatry
Hercher C, Abajian G, Davoli MA, Turecki G, Mechawar N.   +4 more
europepmc   +1 more source