Results 51 to 60 of about 20,611 (249)

Effect of Constitutive Equations on Springback Prediction Accuracy in the TRIP1180 Cold Stamping

Metals, 2017
This study aimed to evaluate the effect of constitutive equations on springback prediction accuracy in cold stamping with various deformation modes. This study investigated the ability of two yield functions to describe the yield behavior: Hill’48 and ...
Ki-Young Seo, Jae-Hong Kim, Hyun-Seok Lee, Ji Hoon Kim, Byung-Min Kim   +4 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Elastic analysis of uniform pressurized axisymmetric cylindrical shells made of saturated porous materials

Results in Physics
In this present research, for the first time, the elastic analysis of uniform pressurized axisymmetric cylindrical shells made of saturated porous materials is studied.
Hooman Esfandyari, Mohammad Zamani Nejad
doaj   +1 more source

On a micropolar theory of growing solids

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2020
The present paper is devoted to the problem of boundary conditions formulation in the growing micropolar solid mechanics. The static equations of the micropolar continuum in terms of relative tensors (pseudotensors) are derived due to virtual work ...
Eugenii Valeryevich Murashkin, Yuri Nikolaevich Radayev   +1 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Heat-Flux Relaxation and the Possibility of Spatial Interactions in Higher-Grade Materials

Mathematics
We investigate the thermodynamic compatibility of weakly nonlocal materials with constitutive equations depending on the third spatial gradient of the deformation and the heat flux ruled by an independent balance law.
Vito Antonio Cimmelli
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

On a differential constraint in the continuum theory of growing solids

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2019
The present paper is devoted to the problem of boundary conditions formulation for asymmetric problems in the mechanics of growing solids (MGS). The boundary conditions on the propagating growing surface (PGS) is the fundamental problem of this branch ...
Eugenii Valeryevich Murashkin, Yuri Nikolaevich Radayev   +1 more
doaj   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source