Results 61 to 70 of about 656,425 (290)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Tuning into flavor: predicting coffee sensory attributes from EEG with boosted-tree regression models

Frontiers in Human Neuroscience
Flavor, a multimodal perception based on taste, smell, and tactile cues, plays a significant role in consumer preferences and purchase intentions toward coffee.
Marco Bilucaglia, Marco Bilucaglia, Mara Bellati, Alessandro Fici, Alessandro Fici, Alessandro Fici, Vincenzo Russo, Vincenzo Russo, Margherita Zito, Margherita Zito   +9 more
doaj   +1 more source

Estimating Demand for Dynamic Pricing in Electronic Markets [PDF]

, 2011
Economic theory suggests sellers can increase revenue through dynamic pricing; selling identical goods or services at different prices. However, such discrimination requires knowledge of the maximum price that each consumer is willing to pay; information ...
Cartlidge, J, Phelps, Steve
core   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Snack Confusion: Parents perceive baby, child and adult snacks as more similar than they actually are

Current Research in Food Science
The consumption of commercial snacks for infants and toddlers has risen significantly, yet limited research has explored how parents evaluate these products across age groups. This study examined parental perceptions of snacks marketed for babies (
Alenica Hässig-Wegmann, Sergio Román, Luisma Sanchez-Siles, Michael Siegrist   +3 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Danish consumers’ knowledge about and willingness to buy dairy products close to the best‐before‐date

Food Frontiers
More than 700,000 tons of food are wasted annually in Denmark where dairy products are among the 10 most wasted food products. Therefore, this study aims to analyze Danish consumers’ understanding of the best‐before‐date label and relational patterns for
Carina V. Melgaard, Emily Voss, Majken F. Hansen, Marlene Lassen, Michelle Hvidtfeldt, Sujita Pandey, Morten Arendt Rasmussen, Marianne Thomsen   +7 more
doaj   +1 more source

Gianluigi Zenti, President, Academia Barilla SpA - The Changing Consumer: Demanding but Predictable [PDF]

It is crucial to understand and predict consumers' behaviour to meet future consumer demands. This report contributes to the discussion by giving an insight into consumers' behaviour from the perspective of Gianluigi Zenti, executive director of Academia
Hartl, Jochen
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source