Results 41 to 50 of about 603,676 (305)
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Why (and When) are Preferences Convex? Threshold Effects and Uncertain Quality [PDF]
, 2008 It is often assumed (for analytical convenience, but also in accordance with common intuition) that consumer preferences are convex. In this paper, we consider circumstances under which such preferences are (or are not) optimal.
Smith, Trenton G., Tasnádi, Attila
core +2 more sources
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
SepaLarge red chili is a high value horticultural commodity that plays a vital role in meeting Indonesia's food demands, both for domestic consumption and industrial purposes.
Idham Parhanudin, Zumi Saidah
doaj +1 more source
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Consumer Personality Traits vs. their Preferences for the Characteristics of Wood Furniture Products
BioResources, 2023 Individual personality traits are powerful determinants of behavior, and they can profoundly influence consumer decisions as a comprehensive understanding of consumer personality traits.
Shulan Yu +4 more
doaj +2 more sources
Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz +11 more
wiley +1 more source
Consumer preferences for parcel delivery methods
European Journal of Transport and Infrastructure Research, 2022 In the Netherlands, as in many other densely populated countries, home delivery is the dominant way of delivering online ordered parcels. This is mainly because big retail companies offer this delivery option for free. Due to the expansion of e-commerce,
Eric Molin +2 more
doaj +1 more source
Experimental auctions, collective induction and choice shift: willingness-to-pay for rice quality in Senegal [PDF]
, 2012 We propose a collective induction treatment as an aggregator of information and preferences, which enables testing whether consumer preferences for food quality elicited through experimental auctions are robust to aggregation.
Demont, Matty +5 more
core +1 more source
On the imprecision of consumer's spatial preferences [PDF]
Papers of the Regional Science Association, 1979 Faced with a set of needs of different intensities and which he perceives more or less indistinctly, a consumer is not normally capable of selecting among the elements belonging to his set of possible consumptions, those he prefers or is indifferent to and those from which he is likely to derive utility.
openaire +2 more sources