Results 81 to 90 of about 5,939,148 (283)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Knowledge Acquisition for Content Selection

open access: yes, 1997
An important part of building a natural-language generation (NLG) system is knowledge acquisition, that is deciding on the specific schemas, plans, grammar rules, and so forth that should be used in the NLG system.
Cawsey, Alison   +3 more
core   +3 more sources

The Importance of Content Knowledge for Successful Legal Language Acquisition [PDF]

open access: yes, 2011
This paper examines what implications this interconnection between language and law has on the process of legal language instruction and acquisition. How important is the knowledge of legal content for successful acquisition of legal terminology? What is
Husinec, Snježana
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

PERSPECTIVES OF EFL TEACHERS ON CONTENT KNOWLEDGE, TECHNOLOGICAL CONTENT KNOWLEDGE, AND PEDAGOGICAL CONTENT KNOWLEDGE

open access: yesEuropean Journal of English Language Teaching
A qualitative study was conducted in a Vietnamese city to investigate the EFL teachers’ perspectives on CK, TCK, and PCK. Qualitative data revealed that integrating Technological Pedagogical Content Knowledge (TPACK) into English teaching practices is considered time-consuming, impeded by factors such as time constraints and students' cognitive ...
openaire   +1 more source

Transforming pre-service teacher curriculum: observation through a TPACK lens [PDF]

open access: yes, 2010
This paper will discuss an international online collaborative learning experience through the lens of the Technological Pedagogical Content Knowledge (TPACK) framework.
Lock, Jennifer V., Redmond, Petrea
core  

Management Knowledge and Knowledge Management: Realism and Forms of Truth [PDF]

open access: yes, 2008
This paper addresses the issue of truth and knowledge in management generally and knowledge management in particular. Based on ideas from critical realism and critical theory, it argues against the monovalent conceptualization of knowledge implicitly or ...
Mingers, John
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Initial knowledge states about assessment [PDF]

open access: yes, 2004
To describe their knowledge of assessment, specifically prepared scripts from 30 novice teachers were content analysed. Knowledge of the formative-summative mode was evident in all scripts but the connections made between this mode of assessment and the ...
Maclellan, Effie
core   +1 more source

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