Results 61 to 70 of about 367 (113)
BackgroundInitial choices of antimicrobial therapy for most cases of community-acquired pneumonia (CAP) in children under 5 years of age are typically based on local epidemiology, risk factors assessment, and subsequent clinical parameters and positive ...
Hui-Ying Liu +15 more
doaj +1 more source
BackgroundInitial choices of antimicrobial therapy for most cases of community-acquired pneumonia (CAP) in children under 5 years of age are typically based on local epidemiology, risk factors assessment, and subsequent clinical parameters and positive ...
Yan Gao (93649) +15 more
core +1 more source
BackgroundInitial choices of antimicrobial therapy for most cases of community-acquired pneumonia (CAP) in children under 5 years of age are typically based on local epidemiology, risk factors assessment, and subsequent clinical parameters and positive ...
Yan Gao (93649) +15 more
core +1 more source
Purpose: Current treatment options for infections caused by vancomycin-resistant (VR) Enterococcus faecium remain limited and often suboptimal. This study investigates the in vitro activity of combination therapies involving fosfomycin and oxazolidinones
Zerbato, Verena +3 more
core +1 more source
New Oxazolidinones for Tuberculosis: Are Novel Treatments on the Horizon?
Multidrug-resistant tuberculosis (MDR-TB) is a global health concern. Standard treatment involves the use of linezolid, a repurposed oxazolidinone. It is associated with severe adverse effects, including myelosuppression and mitochondrial toxicity.
Davies, Forsman L, +4 more
core +2 more sources
IntroductionDisseminated Bacillus Calmette–Guérin (BCG) disease is a rare but life-threatening complication in children with primary immunodeficiency (PID). Linezolid (LZD) is effective but limited by myelosuppression.
Zhen Zhang +7 more
doaj +1 more source
Current Advances in Developing New Antimicrobial Agents Against Non-Tuberculous Mycobacterium
Non-tuberculous mycobacteria (NTM) comprise more than 190 species capable of causing severe pulmonary, lymphatic, cutaneous, and disseminated infections, particularly in immunocompromised populations.
Rahman, Khondaker Miraz +5 more
core +1 more source
Oxazolidinones, novel synthetic antibacterials, inhibit protein biosynthesis and show potent activity against Gram-positive bacteria, including Mycobacterium tuberculosis (MTB).
Jinhui Dong +9 more
core +1 more source

