Results 51 to 60 of about 367 (113)

Clinical Utility of Contezolid-Containing Regimens in 25 Cases of Linezolid-Intolerable Tuberculosis Patients

Infection and Drug Resistance, 2023
Jun Wang,1 Wenjuan Nie,1 Liping Ma,1 Qiang Li,1 Ruixue Geng,2 Wenhui Shi,1 Naihui Chu1 1Department of Tuberculosis, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, People’s Republic
Wang J, Nie W, Ma L, Li Q, Geng R, Shi W, Chu N   +6 more
doaj  

Epstein–Barr Virus‐Positive B‐Cell Lymphoproliferative Disorder Complicated by Septic Shock in Activated PI3Kδ Syndrome: A Pediatric Case Report and Literature Review

Case Reports in Hematology, Volume 2026, Issue 1, 2026.
Activated phosphoinositide 3‐kinase delta syndrome (APDS) is a rare inborn error of immunity caused by gain‐of‐function variants in PIK3CD and characterized by recurrent infections, lymphoproliferation, and impaired viral control. We report a 17‐year‐old male with a heterozygous PIK3CD c.3061G > A (p.E1021K) variant who presented with progressive edema,
Xumeng Zhao, Xi Ming, Zhen Shang, Mi Zhou, Yi Xiao, Kalyani Sen   +5 more
wiley   +1 more source

In-vitro antimicrobial activity of new antimicrobial agents against Streptococcus pneumoniae and potential resistance mechanisms: a multicenter study. [PDF]

BMC Microbiol
Background Streptococcus pneumoniae is a major cause of invasive and non-invasive diseases, particularly in children and immunocompromised individuals, with an annual mortality of approximately 800,000 children worldwide. The rise of antibiotic-resistant
Lei Z, Liu Q, Ma Y, Yang X, Zu H, Li Z, Zhang F, Pu D, Zhang Y, Lu B.   +9 more
europepmc   +2 more sources

Severe Community-Acquired Pneumonia Caused by Methicillin-Sensitive Staphylococcus aureus: Successfully Treated with Contezolid – A Case Report and Literature Review

Infection and Drug Resistance, 2023
Kaifei Wang, Ye Hu, Zhimei Duan, Han Fu, Xingshuo Hu, Ying Zhao, Ruoxuan Wen, Lina Li, Fei Xie College of Pulmonary and Critical Care Medicine, Chinese PLA General Hospital, Beijing, People’s Republic of ChinaCorrespondence: Fei Xie, College of Pulmonary
Wang K, Hu Y, Duan Z, Fu H, Hu X, Zhao Y, Wen R, Li L, Xie F   +8 more
doaj  

Oxazolidinone Antibiotics: Chemical, Biological and Analytical Aspects

, 2021
This review covers the main aspects concerning the chemistry, the biological activity and the analytical determination of oxazolidinones, the only new class of synthetic antibiotics advanced in clinical use over the past 50 years.
Angela Scala, Ottavia Giuffrè, Claudia Foti, Anna Piperno   +3 more
core   +1 more source

In Vitro and In Vivo Activities of Contezolid (MRX-I) against Mycobacterium tuberculosis

, 2018
The in vitro activity of contezolid (MRX-I) against clinical isolates of Mycobacterium tuberculosis was evaluated using a microtiter broth dilution assay. MRX-I was as effective as linezolid (LZD)
Michael Cynamon, Barry Hafkin, Michelle DeStefano, Carolyn Shoen   +3 more
core   +1 more source

Efficacy and safety of contezolid-containing treatment in treating Gram-positive bacterial bloodstream infections following cardiac surgery: A single-center real-world experience

International Journal of Infectious Diseases
Objectives: This study aimed to evaluate the real-world feasibility of contezolid-containing treatment in patients with Gram-positive bacterial bloodstream infections (GPB-BSIs) following cardiac surgery.
Yan Wang, Yong Chen, Fei Li, Peixi Zhou, Jinghan Lei, Shunyao Cui, Xiaofang Ye, Yuanxing Wu   +7 more
doaj   +1 more source

Sequential Therapy of Linezolid and Contezolid to Treat Vancomycin-Resistant Enterococcus faecium Pneumonia in a Centenarian Patient: Case Report [Corrigendum]

Infection and Drug Resistance, 2023
Chen P, An L, Zhang Z. Infect Drug Resist. 2023;16:1573–1578. Page 1575, paragraph two, line 10, the text “(600 mg IV q12d)” should read “(600 mg IV q12h)”. Page 1575, paragraph two, line 12, the text “(400 mg PO
Chen P, An L, Zhang Z
doaj  

Sepsis and pneumonia caused by Enterococcus faecium following liver transplantation treated with contezolid as the first-line therapy

Journal of Global Antimicrobial Resistance
Background: Enterococcus faecium (E. faecium) stands as a prominent pathogen contributing to Gram-positive bacterial infections in individuals who have undergone liver transplantation.
Xiangyan Liu, Zhuoyi Wang, Weilin Wu, Shusen Zheng   +3 more
doaj   +1 more source

Image3_Compassionate use of contezolid in a toddler with severe community-acquired pneumonia induced by staphylococcus aureus: a case report and follow-up.tif

BackgroundInitial choices of antimicrobial therapy for most cases of community-acquired pneumonia (CAP) in children under 5 years of age are typically based on local epidemiology, risk factors assessment, and subsequent clinical parameters and positive ...
Yan Gao (93649), Kai Kang (195645), Yu-Cheng Zhu (9676980), Ya-Jun Wang (137203), Huan Meng (231636), Hong Zhang (25820), Shu-Xiao Qiu (17915345), Xiao-Fei Bi (17915333), Yi-Lu Lin (17915339), Feng-Jie Xie (17915336), Hui-Ying Liu (10193468), Yan Zhang (8098), Lin-Qiong Liu (17915342), Zhi-Hui Wang (700100), Di Wu (23906), Yang Gao (18005)   +15 more
core   +1 more source