Results 1 to 10 of about 1,053,987 (300)

Long noncoding RNAs and metabolic memory associated with continued progression of diabetic retinopathy [PDF]

open access: yesJournal of Diabetes
Progression of diabetic retinopathy resists arrest even after institution of intensive glycemic control, suggesting a “metabolic memory” phenomenon, but the mechanism responsible for this phenomenon is still elusive.
Jay Kumar   +2 more
doaj   +2 more sources

Prolonged exposure to cocaine self-administration results in a continued progression of alterations in functional activity in a nonhuman primate model [PDF]

open access: yesDrug and Alcohol Dependence Reports, 2023
Background: Studies of nonhuman primates with exposures of up to 100 days of cocaine self-administration (SA) have provided evidence that the central effects of cocaine progress over time. These durations of cocaine exposure, however, may be insufficient
Linda J. Porrino   +5 more
doaj   +2 more sources

Two case reports of continued progression of chronic ocular graft-versus-host disease without concurrent systemic comorbidities treated by amniotic membrane transplantation [PDF]

open access: yesBMC Ophthalmology, 2021
Background Chronic ocular graft-versus-host disease (oGVHD) is an ocular comorbidity of graft-versus-host disease (GVHD) that usually occurs concurrently with systemic manifestations.
Hideto Ikarashi   +9 more
doaj   +2 more sources

Mogamulizumab plus etoposide in the management of mycosis fungoides with blood involvement: a case report [PDF]

open access: yesTherapeutic Advances in Hematology
Mycosis fungoides (MF) and Sézary syndrome are primary cutaneous T-cell lymphomas with widely varying courses of disease and prognosis. Here, we report the case of a patient with MF with blood involvement who experienced many lines of skin-directed and ...
Daniel Nieto Rodríguez   +1 more
doaj   +2 more sources

Role of progression of training volume on intramuscular adaptations in patients with chronic obstructive pulmonary disease

open access: yesFrontiers in Physiology, 2022
Introduction: Quadriceps dysfunction is a common systemic manifestation of chronic obstructive pulmonary disease (COPD), for which treatment using resistance training is highly recommended. Even though training volume is suggested to be a key explanatory
Andre Nyberg   +7 more
doaj   +1 more source

Progression Patterns, Treatment, and Prognosis Beyond Resistance of Responders to Immunotherapy in Advanced Non-Small Cell Lung Cancer

open access: yesFrontiers in Oncology, 2021
IntroductionImmune checkpoint inhibitors (ICIs) have changed the management of non-small cell lung cancer (NSCLC). However, resistance is inevitable.
Yanjun Xu, Hui Li, Yun Fan
doaj   +1 more source

Impact of the treatment crossover design on comparative efficacy in EMPOWER-Lung 1: Cemiplimab monotherapy as first-line treatment of advanced non-small cell lung cancer

open access: yesFrontiers in Oncology, 2023
ObjectivesIn randomized-controlled crossover design trials, overall survival (OS) treatment effect estimates are often confounded by the control group benefiting from treatment received post-progression.
Josephine Louella Feliciano   +13 more
doaj   +1 more source

Home - About - Disclaimer - Privacy