Long noncoding RNAs and metabolic memory associated with continued progression of diabetic retinopathy [PDF]
Progression of diabetic retinopathy resists arrest even after institution of intensive glycemic control, suggesting a “metabolic memory” phenomenon, but the mechanism responsible for this phenomenon is still elusive.
Jay Kumar +2 more
doaj +2 more sources
Prolonged exposure to cocaine self-administration results in a continued progression of alterations in functional activity in a nonhuman primate model [PDF]
Background: Studies of nonhuman primates with exposures of up to 100 days of cocaine self-administration (SA) have provided evidence that the central effects of cocaine progress over time. These durations of cocaine exposure, however, may be insufficient
Linda J. Porrino +5 more
doaj +2 more sources
Two case reports of continued progression of chronic ocular graft-versus-host disease without concurrent systemic comorbidities treated by amniotic membrane transplantation [PDF]
Background Chronic ocular graft-versus-host disease (oGVHD) is an ocular comorbidity of graft-versus-host disease (GVHD) that usually occurs concurrently with systemic manifestations.
Hideto Ikarashi +9 more
doaj +2 more sources
Mogamulizumab plus etoposide in the management of mycosis fungoides with blood involvement: a case report [PDF]
Mycosis fungoides (MF) and Sézary syndrome are primary cutaneous T-cell lymphomas with widely varying courses of disease and prognosis. Here, we report the case of a patient with MF with blood involvement who experienced many lines of skin-directed and ...
Daniel Nieto Rodríguez +1 more
doaj +2 more sources
Retinal Mitochondrial DNA Mismatch Repair in the Development of Diabetic Retinopathy, and Its Continued Progression After Termination of Hyperglycemia [PDF]
Manish Mishra, Renu A Kowluru
exaly +2 more sources
Mitochondria DNA Replication and DNA Methylation in the Metabolic Memory Associated with Continued Progression of Diabetic Retinopathy [PDF]
Shikha Tewari +2 more
exaly +2 more sources
The Role of DNA Methylation in the Metabolic Memory Phenomenon Associated With the Continued Progression of Diabetic Retinopathy [PDF]
Manish Mishra, Renu A Kowluru
exaly +2 more sources
Introduction: Quadriceps dysfunction is a common systemic manifestation of chronic obstructive pulmonary disease (COPD), for which treatment using resistance training is highly recommended. Even though training volume is suggested to be a key explanatory
Andre Nyberg +7 more
doaj +1 more source
IntroductionImmune checkpoint inhibitors (ICIs) have changed the management of non-small cell lung cancer (NSCLC). However, resistance is inevitable.
Yanjun Xu, Hui Li, Yun Fan
doaj +1 more source
ObjectivesIn randomized-controlled crossover design trials, overall survival (OS) treatment effect estimates are often confounded by the control group benefiting from treatment received post-progression.
Josephine Louella Feliciano +13 more
doaj +1 more source

