Results 21 to 30 of about 422,013 (303)

Mitochondrial Dynamics in the Metabolic Memory of Diabetic Retinopathy

Journal of Diabetes Research, 2022
Mitochondria play a central role in the development of diabetic retinopathy and in the metabolic memory associated with its continued progression. Mitochondria have a regulated fusion fission process, which is essential for their homeostasis.
Ghulam Mohammad, Renu A. Kowluru
doaj   +1 more source

A progressão continuada no estado de São Paulo: considerações a partir da perspectiva de educadores

Psicologia Escolar e Educacional
Este estudo analisou a Progressão Continuada na perspectiva de educadores do ensino fundamental. O método utilizado foi a realização de redações e grupos de reflexão visando conhecer como os educadores compreendem a política educacional, como a ...
Lygia de Sousa Viégas, Marilene Proença Rebello de Souza   +1 more
doaj   +3 more sources

Continued gefitinib retreatment beyond progression in patients with advanced non-small cell lung cancer harboring sensitive mutations

Journal of International Medical Research, 2020
Purpose To evaluate the effectiveness and safety of gefitinib retreatment beyond disease progression in patients with advanced non-small cell lung cancer (NSCLC) with sensitive epidermal growth factor receptor ( EGFR ) mutations.
Xuhong Jiang, Xiaoqing Li, Lingli Tu, Jin Cai, Man Wei, Zhongjun Wu, Lan Sun   +6 more
doaj   +1 more source

Intermittent induction of HIF-1α produces lasting effects on malignant progression independent of its continued expression.

PLoS ONE, 2015
Dysregulation of hypoxia-inducible transcription factors HIF-1α and HIF-2α correlates with poor prognosis in human cancers; yet, divergent and sometimes opposing activities of these factors in cancer biology have been observed.
Hyunsung Choi, David L Gillespie, Shauna Berg, Christopher Rice, Sandrine Couldwell, Jie Gu, Howard Colman, Randy L Jensen, L Eric Huang   +8 more
doaj   +1 more source

[How should hormone therapy for castration-resistant prostate cancer be continued?] [PDF]

, 2012
After an average of 18-36 months under androgen suppression therapy by surgical castration, LHRH, and steroidal or non-steroidal antiandrogens, almost all patients with metastatic prostate cancer show PSA progression as a sign of androgen-independent but
Spahn, M, Krebs, M
core   +1 more source

Continued growth, continual progress, and continuous publications [PDF]

Metabolomics, 2015
Welcome to the twelfth volume of the new look Metabolomics. 2016 is an exciting time for metabolomics in terms of the continued growth and continual progress being made within all areas of this vibrant research field. Approximately 10,000 articles have been published per annum in the last 3 years, and this is likely to increase further.
openaire   +2 more sources

Sacroiliac joint radiographic progression in axial spondyloarthritis is retarded by the therapeutic use of TNF inhibitors: 12-year data from the SCQM registry [PDF]

, 2022
OBJECTIVES: To analyse the effect of tumour necrosis factor inhibitors (TNFi) on sacroiliac joint (SIJ) radiographic progression in axial spondyloarthritis (axSpA).
Bräm, René, Andor, Michael, Micheroli, Raphael, Kissling, Seraphina, Distler, Oliver, Nissen, Michael J, Exer, Pascale, Scherer, Almut, Ciurea, Adrian, Bürki, Kristina, Möller, Burkhard   +10 more
core   +1 more source

Educar sem reprovar: desafio de uma escola para todos Educating without failing: a challenge to a school for everyone

Educação e Pesquisa, 2009
Neste artigo, discute-se a realização do direito à educação e a forma de organização do ensino na perspectiva de democratizá-la. Tem-se como pressuposto que os ciclos e a progressão continuada podem ser uma forma de organização do ensino que favorece a ...
Márcia Aparecida Jacomini
doaj   +1 more source

Continued Use of Trastuzumab Beyond Disease Progression in the National Comprehensive Cancer Network: Should We Practice Ahead of the Evidence?

, 2011
Background. The role of continued trastuzumab after progression in women with human epidermal growth factor receptor (HER)-2+ metastatic breast cancer is controversial.
Jane C. Weeks, Richard Theriault, Melissa E. Hughes, Douglas Blayney, Joyce C. Niland, Stephen B. Edge, Rebecca A. Ottesen, Yu-Ning Wong   +7 more
core   +1 more source

Risk factors and clinical outcomes of systemic cancer treatment delays in Filipino patients with solid tumor malignancy during the COVID‐19 pandemic: A single tertiary center study

Cancer Reports, 2022
Background Cancer care during the Covid‐19 pandemic has been challenging especially in a developing country such as the Philippines. Oncologists were advised to prioritize chemotherapy based on the absolute benefit that the patient may receive, which ...
Jessa Gilda Pandy, Omar Maaño, Joanmarie C. Balolong‐Garcia, Jay T. Y. Datukan   +3 more
doaj   +1 more source