Epikeratophakia for Keratoconus: A Case Report with 30 Years of Follow-Up
Background. Epikeratophakia is a refractive surgical procedure used to correct aphakic eyes, hyperopia, and keratoconus and is often performed in children.
Takashi Miyai +7 more
doaj +1 more source
Role of Mitochondria Biogenesis in the Metabolic Memory Associated with the Continued Progression of Diabetic Retinopathy and Its Regulation by Lipoic Acid [PDF]
Julia Santos, Renu A Kowluru
exaly +2 more sources
Formação por ciclos Formation by cycles
Artigo desenvolvido a partir dos estudos de Mestrado na Universidade Federal do Paraná, na linha de pesquisa Currículo, Conhecimento e Saberes nas Práticas Escolares, investigando a Formação por Ciclos.
Lidia Nedbajluk
doaj +1 more source
HERMIONE: a randomized Phase 2 trial of MM-302 plus trastuzumab versus chemotherapy of physician's choice plus trastuzumab in patients with previously treated, anthracycline-naïve, HER2-positive, locally advanced/metastatic breast cancer. [PDF]
BackgroundHuman epidermal growth factor receptor 2 (HER2)-positive breast cancer is a particularly aggressive form of the disease, and ultimately progresses in patients with metastases on standard therapies.
Cortes, Javier +10 more
core +2 more sources
Este artigo aborda a compreensão da avaliação no interior da implantação do Regime de Progressão Continuada no Estado de São Paulo. Ao penetrar nos intrincados caminhos da realidade escolar, por meio da pesquisa qualitativa, acompanharam-se ...
Regiane Helena Bertagna
doaj +1 more source
Interferon β-1a in relapsing multiple sclerosis: four-year extension of the European IFNβ-1a Dose-C omparison Study [PDF]
Background: Multiple sclerosis (MS) is a chronic disease requiring long-term monitoring of treatment. Objective: To assess the four-year clinical efficacy of intramuscular (IM) IFNb-1a in patients with relapsing MS from the European IFNb-1a Dose-C ...
Achiti, J. +98 more
core +1 more source
Obeticholic acid for the treatment of primary biliary cholangitis in adult patients: clinical utility and patient selection. [PDF]
Primary biliary cholangitis (PBC), previously known as primary biliary "cirrhosis", is a rare autoimmune liver disease characterized by the hallmark autoantibodies to mitochondrial antigens and immune-mediated destruction of small bile duct epithelial ...
Bowlus, Christopher L
core +3 more sources
Neste artigo discute-se a atuação dos educadores no processo de implementação dos ciclos e da progressão continuada nas redes públicas de ensino municipal e estadual de São Paulo em quatro momentos distintos: na Reforma de 67/68, na implantação do Ciclo ...
Márcia Aparecida Jacomini
doaj +1 more source
Possible association of keratoconus progression with gender-affirming hormone therapy: A case report
Purpose: To present a case of keratoconus progression following gender-affirming hormone therapy. Observations: A 28-year-old male-to-female transgender patient with potential past ocular history of subclinical keratoconus presented with subacute ...
Carli M. Deitel +2 more
doaj +1 more source
BMP2/BMPR1A is linked to tumour progression in dedifferentiated liposarcomas [PDF]
Bone Morphogenic Protein 2 (BMP2) is a multipurpose cytokine, important in the development of bone and cartilage, and with a role in tumour initiation and progression.
Cassidy, A.P. +3 more
core +3 more sources

