Results 101 to 110 of about 8,918,982 (409)

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

ON THE DIAGNOSTICS OF SAGITTAL OCCLUSION ANOMALIES

Acta Biomedica Scientifica, 2015
In the known classifications, there is no terminological wording as asymmetrical sagittal occlusion of segments of dentition in lateral areas. The work complemented classification of sagittal occlusion anomalies in the lateral areas of dentition of ...
P. A. Kovtonyuk, G. I. Sablina, N. N. Soboleva   +2 more
doaj  

Heparin enables the reliable detection of endotoxin in human serum samples using the Limulus amebocyte lysate assay

Scientific Reports
The determination of lipopolysaccharide (endotoxin) in serum or plasma samples using Limulus amebocyte lysate (LAL)-based assays is currently not sufficiently reliable in clinical diagnostics due to numerous interfering factors that strongly reduce the ...
Stephan Harm, Claudia Schildböck, Denisa Cont, Viktoria Weber   +3 more
doaj   +1 more source

Predicting the risk of developing drug-induced liver injury during remdesivir therapy in COVID-19 patients using machine learning

Acta Biomedica Scientifica
Background. The antiviral drug Remdesivir has been widely used for etiotropic treatment of COVID-19. The incidence of adverse reactions during Remdesivir therapy reaches 66.2 %, the most common one being an increase in hepatic transaminases.The aim.
Yu. V. Shevchuk, I. I. Shamigulov, I. V. Sychev, A. V. Kryukov, I. I. Temirbulatov, K. B. Mirzaev, N. P. Denisenko, Sh. P. Abdullaev, S. N. Tuchkova, V. I. Vechorko, O. V. Averkov, D. A. Sychev   +11 more
doaj   +1 more source

New Research Provides Solutions to the Nursing Shortage: Improving Retention of Older and Experienced Nurses in the Workforce [PDF]

, 2008
Outlines research findings on how early retirement contributes to the shortage of nurses and on incentives that help retain experienced nurses, including financial support for continuing education and redesigned work spaces, hours, and benefit ...

core  

Continuing education: The 1998 survey of the Royal Australasian College of Dental Surgeons [PDF]

, 2001
The document attached has been archived with permission from the Australian Dental Association. An external link to the publisher’s copy is included.Background: Continuing education (CE) is an essential professional activity.
Bastiaan, R., Goss, A., Sambrook, P., Thomson, D.   +3 more
core   +2 more sources

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Clinical and roentgenological aspects of diagnosis and treatment of temporomandibular joint pathology

Acta Biomedica Scientifica, 2013
The article presents the occurrence of temporomandibular joint pathology (20,9 %) in children of prepubertal age. It was revealed that habitual dislocation that appears on the background of asymmetric occlusion with close position of teeth in frontal and
G. I. Sablina, P. A. Kovtonyuk, N. N. Soboleva   +2 more
doaj  

Continuing Education: Continuing Education at Harvard

College & Research Libraries News, 1980
Continuing Education: Continuing Education at ...
openaire   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source