Results 101 to 110 of about 9,016,160 (399)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Scientific ReportsThe determination of lipopolysaccharide (endotoxin) in serum or plasma samples using Limulus amebocyte lysate (LAL)-based assays is currently not sufficiently reliable in clinical diagnostics due to numerous interfering factors that strongly reduce the ...
Stephan Harm +3 more
doaj +1 more source
Global Journal of Health Science, 2014 Background: Since several factors affect nurses’ participation in Continuing Education, and that nurses’ Continuing Education affects patients’ and community health status, it is essential to know facilitators and barriers of participation in Continuing ...
Z. Shahhosseini, Z. Hamzehgardeshi
semanticscholar +1 more source
Universities in the Market for Continuing Higher Education [PDF]
The purpose of the paper is to explain why and how American universities have taken the lead in continuing education compared to their European counterparts.
Bettina Wentzel, Mark Oelmann
core
New Research Provides Solutions to the Nursing Shortage: Improving Retention of Older and Experienced Nurses in the Workforce [PDF]
, 2008 Outlines research findings on how early retirement contributes to the shortage of nurses and on incentives that help retain experienced nurses, including financial support for continuing education and redesigned work spaces, hours, and benefit ...
core
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
BMC Family Practice, 2019 Background Evidence-based medicine (EBM) is gradually being recognized worldwide as an important clinical skill and plays an important role in health care.
Yali Zhao +6 more
doaj +1 more source
Online from Across the Pond [PDF]
, 2017 When Hayley Carroll ’18 decided to return to college, an ocean separated her from the American system where she already had her higher-education start. But that didn’t stop her.
Davis, Laura
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
, 2017 After a long night of body checks, slapshots and chasing a puck up and down the ice, Michael McCurtain ’16 often retreated to his hotel room – to tackle accounting homework.
Davis, Laura
core +1 more source