Results 111 to 120 of about 318,392 (311)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

高敏感特質中高齡學習者面對數位學習壓力及疫情焦慮之學習滿意度與後疫情調適:復原力之中介效果 Learning Satisfaction and Post-Pandemic Adaptation in Highly Sensitive Middle-aged and Elderly Learners in the Face of Digital Learning Stress and Pandemic Anxiety

open access: yesJournal of Research in Education Sciences
人口老化趨勢及近年疫情大流行加速了中高齡數位學習之推動與普及,在此環境改變下,對高敏感特質的長輩是一大考驗。本研究旨在探討高敏感特質之中高齡者於疫情變化使數位學習環境更為普及之狀況下,所產生的數位學習壓力、心理憂鬱及學習滿意度的關聯,並以復原力作為中介變項,最後亦探討疫情趨緩後中高齡者在後疫情之感受。本研究採用問卷調查法進行資料蒐集,研究工具為高敏感特質、疫情焦慮、數位學習壓力、憂鬱情緒量表、學習滿意度、復原力及後疫情正向感受等7份量表;以45歲以上有數位學習經驗的中高齡者為研究對象 ...
王雅鈴 Ya-Ling Wang   +3 more
doaj   +1 more source

Aligning Continuing Education Units and Universities: Survival Strategies for the New Millennium [PDF]

open access: yes, 2001
The goal of the study presented in this paper was to understand and to start to document the contributions that a continuing education unit (CEU) makes to the university. Although continuing education contributes in both financial and non-financial ways,
Petersen, Nancy
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Clinical case of liver transplantation in a kidney transplant recipient with hepatocellular cancer and сoronary artery disease

open access: yesВестник трансплантологии и искусственных органов
Objective: organ transplantation is a highly effective and often the only possible definitive treatment for terminal diseases, significantly improving patient survival and quality of life.
A. V. Shabunin   +10 more
doaj   +1 more source

Understanding Quantitative Circadian Regulations Are Crucial Towards Advancing Chronotherapy

open access: yesCells, 2019
Circadian rhythms have a deep impact on most aspects of physiology. In most organisms, especially mammals, the biological rhythms are maintained by the indigenous circadian clockwork around geophysical time (~24-h).
Debajyoti Chowdhury   +3 more
doaj   +1 more source

The Characteristics of Continuing Professional Education Systems in the Health Professions in Canada [PDF]

open access: yes, 2006
Mandatory continuing education (MCE) has become widely accepted across many professions and jurisdictions in Canada as a re-credentialing mechanism. MCE is defined as continuing professional education (CPE) courses and/or programs, beyond the entry-level
Curran, Vernon, Kirby, Fran, Fleet, Lisa
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Mediational effect analysis of childhood emotional abuse on prodromal psychotic symptoms in self-taught examination students

open access: yesScientific Reports
It has been shown that childhood trauma is associated with an increased risk of prodromal psychotic symptoms. However, research on the prevalence of prodromal psychotic symptoms among self-taught examination students and the relationship with childhood ...
Yanchi Wang   +7 more
doaj   +1 more source

A Comparison of the Organizational Frameworks of Canadian and American University Continuing Education Units [PDF]

open access: yes, 2008
In 2006, a study involving institutional members of the Canadian Association of University Continuing Education (CAUCE) was conducted by the CAUCE Information and Research Committee working in collaboration with the Research Committee of the Association ...
Wilson, Edna   +2 more
core   +1 more source

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