Results 131 to 140 of about 9,016,160 (399)

Diagnosis and management of cystinosis: systematic review for a clinical practice guideline

open access: yesOrphanet Journal of Rare Diseases
Background Cystinosis is a rare genetic disorder, with the majority of patients suffering from infantile nephropathic cystinosis, the most severe form. If left untreated, cystinosis causes serious morbidity, initially through progressive kidney and eye ...
Dominic Ledinger   +7 more
doaj   +1 more source

The Effect of Continuing Education Participation on Agricultural Worker Outcomes [PDF]

open access: yes
Migrant farmworkers are among the poorest members of the working class served by the U.S. public workforce investment system. The National Farmworker Jobs Program (NFJP) provides job training and employment assistance to migrant and seasonal farmworkers ...
Pena, Anita Alves
core   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

Continuing Education: Continuing Education at Harvard

open access: yesCollege & Research Libraries News, 1980
Continuing Education: Continuing Education at ...
openaire   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Mediational effect analysis of childhood emotional abuse on prodromal psychotic symptoms in self-taught examination students

open access: yesScientific Reports
It has been shown that childhood trauma is associated with an increased risk of prodromal psychotic symptoms. However, research on the prevalence of prodromal psychotic symptoms among self-taught examination students and the relationship with childhood ...
Yanchi Wang   +7 more
doaj   +1 more source

高敏感特質中高齡學習者面對數位學習壓力及疫情焦慮之學習滿意度與後疫情調適:復原力之中介效果 Learning Satisfaction and Post-Pandemic Adaptation in Highly Sensitive Middle-aged and Elderly Learners in the Face of Digital Learning Stress and Pandemic Anxiety

open access: yesJournal of Research in Education Sciences
人口老化趨勢及近年疫情大流行加速了中高齡數位學習之推動與普及,在此環境改變下,對高敏感特質的長輩是一大考驗。本研究旨在探討高敏感特質之中高齡者於疫情變化使數位學習環境更為普及之狀況下,所產生的數位學習壓力、心理憂鬱及學習滿意度的關聯,並以復原力作為中介變項,最後亦探討疫情趨緩後中高齡者在後疫情之感受。本研究採用問卷調查法進行資料蒐集,研究工具為高敏感特質、疫情焦慮、數位學習壓力、憂鬱情緒量表、學習滿意度、復原力及後疫情正向感受等7份量表;以45歲以上有數位學習經驗的中高齡者為研究對象 ...
王雅鈴 Ya-Ling Wang   +3 more
doaj   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

DEVELOPMENT OF ELECTRONIC GOVERNMENT AS A DRIVER OF COMPETITIVENESS OF EUROPEAN UNION COUNTRIES

open access: yesПублічне управління та регіональний розвиток
Digital technologies in public administration are a key driver of change in modern society. They contribute to increasing transparency, accessibility of public services and efficiency of interaction between authorities and citizens. The implementation of
Svitlana Rybkina, Elmira Sokolova
doaj   +1 more source

Home - About - Disclaimer - Privacy