Results 121 to 130 of about 5,828,085 (378)

Dexamethasone distribution characteristic following controllable continuous sub-tenon drug delivery in rabbit

Drug Delivery, 2017
Drug delivery systems are required to be safe, minimally invasive and effectively delivery drug to the target tissues. But delivery drugs to the eye has not yet satisfied this need. Here, we focused on examining the distribution of dexamethasone (DEX) in
Xuetao Huang, Manqiang Peng, Yezhen Yang, Yiqin Duan, Kuanshu Li, Shaogang Liu, Changhua Ye, Ding Lin   +7 more
doaj   +1 more source

Ultradian cortisol pulsatility encodes a distinct, biologically important signal.

PLoS ONE, 2011
ContextCortisol is released in ultradian pulses. The biological relevance of the resulting fluctuating cortisol concentration has not been explored.ObjectiveDetermination of the biological consequences of ultradian cortisol pulsatility.DesignA novel flow
Andrew McMaster, Maryam Jangani, Paula Sommer, Namshik Han, Andy Brass, Stephen Beesley, Weiqun Lu, Andrew Berry, Andrew Loudon, Rachelle Donn, David W Ray   +10 more
doaj   +1 more source

Continuous Drug Delivery Aiming Continuous Dopaminergic Stimulation in Parkinson’s Disease

Journal of Parkinson’s Disease, 2018
Continuous dopaminergic stimulation in Parkinson’s disease (PD) has several advantages over pulsatile, non-continuous, stimulation. These therapies currently consist of pump-based and transcutaneous therapies and are based on a more constant delivery of the dopaminergic drug resulting in continuous dopaminergic stimulation and a more stable treatment ...
van Wamelen, Daniel J., Grigoriou, Sotirios, Chaudhuri, K. Ray, Odin, Per   +3 more
openaire   +3 more sources

Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu, Talia Robinson, Marina Rodriguez Alonso, Adela Francis Malave, Roos J. Jutten, Michael J. Properzi, Brian C. Healy, Jackson C. Thompson, Grace Del Carmen Montenegro, Emma Thibault, Dana Penney, Randall Davis, Reisa A. Sperling, Kathryn V. Papp, Keith A. Johnson, Julie C. Price, Dorene M. Rentz   +16 more
wiley   +1 more source

EFFECT OF PAIN RELIEF IN DELIVERY ON THE FREQUENCY OF POSTPARTUM DEPRESSION IN NEW MOTHERS

Вестник анестезиологии и реаниматологии, 2017
The article evaluates the effect of various anesthetic techniques in delivery on the frequency of postpartum depression in new mothers. Materials and methods. 209 women were enrolled into the study, medium age made 31 years and gestation period made 39.4
O. V. Ryazanova, Yu. S. Aleksandrovich, I. A. Gorkovaya, M. A. Korgozha, Yu. V. Koshkina, A. M. Ioskovich   +5 more
doaj   +1 more source

Have we reached proton beam therapy dosimetric limitations? – A novel robust, delivery-efficient and continuous spot-scanning proton arc (SPArc) therapy is to improve the dosimetric outcome in treating prostate cancer [PDF]

, 2017
Xuanfeng Ding, Xiaoqiang Li, An Qin, Jun Zhou, Di Yan, Craig Stevens, Daniel Krauss, Peyman Kabolizadeh   +7 more
openalex   +1 more source

Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Optical coherence tomography (OCT)‐derived retina measurements are markers for neuroaxonal visual pathway status. High‐quality OCT scans are essential for reliable measurements, but their acquisition is particularly challenging in eyes with severe visual impairment, as often observed in neuromyelitis optica spectrum disorders ...
Hadi Salih, Sara Samadzadeh, Charlotte Bereuter, Seyedamirhosein Motamedi, Claudia Chien, Pablo Villoslada, Hadas Stiebel‐Kalish, Nasrin Asgari, Yang Mao‐Draayer, Marius Ringelstein, Joachim Havla, Marco Aurélio Lana Peixoto, Ho Jin Kim, Jacqueline Palace, Maria Isabel Leite, Srilakshmi M. Sharma, Fereshteh Ashtari, Rahele Kafieh, Lekha Pandit, Orhan Aktas, Philipp Albrecht, Letizia Leocani, Itay Lotan, Sasitorn Siritho, Jérôme de Seze, Romain Marignier, Caroline Froment Tilikete, Denis Bernardi Bichuetti, Ivan Maynart Tavares, Ayse Altintas, Anu Jacob, Saif Huda, Ibis Soto de Castillo, Lawrence J. Cook, Michael R. Yeaman, Axel Petzold, Alexander U. Brandt, Friedemann Paul, Frederike C. Oertel, Hanna G. Zimmermann, with the Guthy Jackson Charitable Foundation—International Clinical Consortium and CROCTINO Collaborators   +40 more
wiley   +1 more source

The effect of continuous electronic fetal monitoring on mode of delivery and neonatal outcome among low-risk laboring mothers at Debre Markos comprehensive specialized hospital, Northwest Ethiopia

Frontiers in Global Women's Health
BackgroundElectronic fetal heart rate monitoring (EFM) has been widely used in obstetric practice for over 40 years to improve perinatal outcomes. Its popularity is growing in Ethiopia and other sub-Saharan African countries to reduce high perinatal ...
Tirusew Nigussie Kebede, Kidist Ayalew Abebe, Moges Sisay Chekol, Tebabere Moltot Kitaw, Muhabaw Shumye Mihret, Bezawit Melak Fentie, Yared Alem Sibhat, Michael Amera Tizazu, Solomon Hailemeskel Beshah, Birhan Tsegaw Taye   +9 more
doaj   +1 more source

Continuous hydroponic wheat production using a recirculating system [PDF]

Continuous crop production, where plants of various ages are growing simultaneously in a single recirculating nutrient solution, is a possible alternative to batch production in a Controlled Ecological Life Support System. A study was conducted at John F.
Hinkle, C. R., Mackowiak, C. L., Owens, L. P., Prince, R. P.   +3 more
core   +1 more source

Practicing Continuous Integration Continuous Delivery on AWS

International Journal of Latest Technology in Engineering Management & Applied Science
Abstract: The rapid-fire elaboration of software development methodologies has needed the relinquishment of robotization- driven practices to enhance software quality and delivery speed. Continuous Integration (CI) and Continuous Delivery (CD) are foundation practices in ultramodern DevOps channels, enabling brigades to integrate law constantly, descry
null Sonali P Lohar, null Padmaja D Kadam   +1 more
openaire   +1 more source