Results 41 to 50 of about 244,667 (356)

Differential transport function of lymphatic vessels in the rat tail model and the long-term effects of Indocyanine Green as assessed with near-infrared imaging

Frontiers in Physiology, 2013
Introduction: Near-infrared (NIR) imaging has emerged as a novel imaging modality for assessing lymphatic function in vivo. While the technique has provided quantitative data previously unavailable, questions remain in regards to the spatiotemporal ...
Michael eWeiler, J. Brandon eDixon, J. Brandon eDixon   +2 more
doaj   +1 more source

Hypertrophic and Dilated Cardiomyopathy-Associated Troponin T Mutations R130C and ΔK210 Oppositely Affect Length-Dependent Calcium Sensitivity of Force Generation

Frontiers in Physiology, 2020
Length-dependent activation of calcium-dependent myocardial force generation provides the basis for the Frank-Starling mechanism. To directly compare the effects of mutations associated with hypertrophic cardiomyopathy and dilated cardiomyopathy, the ...
Marcel Groen, Alfredo Jesus López-Dávila, Stefan Zittrich, Gabriele Pfitzer, Robert Stehle   +4 more
doaj   +1 more source

Paracrine HB-EGF signaling reduce enhanced contractile and energetic state of activated decidual fibroblasts by rebalancing SRF-MRTF-TCF transcriptional axis

Frontiers in Cell and Developmental Biology, 2022
Multiple parallels exist between placentation and cancer dissemination at molecular, cellular, and anatomical levels, presenting placentation as a unique model to mechanistically understand the onset of cancer metastasis.
Junaid Afzal, Wenqiang Du, Ashkan Novin, Yamin Liu, Khadija Wali, Anarghya Murthy, Ashley Garen, Gunter Wagner, Gunter Wagner, Kshitiz, Kshitiz   +10 more
doaj   +1 more source

Mechanisms of exercise-induced improvements in the contractile apparatus of the mammalian myocardium [PDF]

, 2010
One of the main outcomes of aerobic endurance exercise training is the improved maximal oxygen uptake, and this is pivotal to the improved work capacity that follows the exercise training.
Adams, Adams, American College of Sports Medicine Position Stand, American Heart Association, Amundsen, Anderson, Anversa, Beisvag, Belardinelli, Bergmann, Bers, Beyer, Blair, Blair, Boluyt, Bossuyt, Bye, Care, de Waard, Del Monte, Diffee, Diffee, Diffee, Diffee, Eto, Fletcher, Frampton, Gledhill, Gomez, Gulati, Hambrecht, Hambrecht, Haram, Hasenfuss, Helgerud, Hunter, Iemitsu, Jensen, Jolliffe, Kavanagh, Kemi, Kemi, Kemi, Kemi, Kemi, Kemi, Kemi, Kemi, Kemi, Kodoma, Kong, Kuum, Lankford, Laughlin, Lee, Levine, Liang, Liu, Loennechen, McMullen, Moholdt, Mokelke, Mole, Moore, Musch, Myers, Myles, Nakao, Natali, O’Connor, O’Neill, Paffenbarger, Palmer, Pelliccia, Penpargkul, Pluim, Richardson, Richardson, Rognmo, Saltin, Schaible, Schjerve, Shephard, Stolen, Tanasescu, Tate, Tibbits, Tjonna, Venetucci, Wagner, Wilkins, Wisloff, Wisloff, Wisloff, Wisloff, Wisloff, Wisloff, Zhang, Zhang   +98 more
core   +1 more source

Viability and Contractility of Rat Brain Pericytes in Conditions That Mimic Stroke; an in vitro Study

Frontiers in Neuroscience, 2019
Reopening of the cerebral artery after occlusion often results in “no-reflow” that has been attributed to the death and contraction (rigor mortis) of pericytes.
Mohammed Heyba, Lulwa Al-Abdullah, Andreas W. Henkel, Zeinab Sayed, Slava A. Malatiali, Zoran B. Redzic   +5 more
doaj   +1 more source

C‐type natriuretic peptide induces inotropic and lusitropic effects in human 3D‐engineered cardiac tissue: Implications for the regulation of cardiac function in humans

Experimental Physiology, 2023
The role of C‐type natriuretic peptide (CNP) in the regulation of cardiac function in humans remains to be established as previous investigations have been confined to animal model systems.
Julian C. Bachmann, Jeppe E. Kirchhoff, Julia E. Napolitano, Steve Sorota, William M. Gordon, Nicole Feric, Roozbeh Aschar‐Sobbi, Juan Lv, Zhiyou Cao, Ken Coppieters, Giulia Borghetti, Michael Nyberg   +11 more
doaj   +1 more source

Active wetting of epithelial tissues

, 2019
Development, regeneration and cancer involve drastic transitions in tissue morphology. In analogy with the behavior of inert fluids, some of these transitions have been interpreted as wetting transitions.
A Ravasio, AF Mertz, AF Mertz, AG Clark, AMJ Edwards, AR Harris, B Smeets, B Wallmeyer, C Blanch-Mercader, C Blanch-Mercader, C Cortina, Carles Blanch-Mercader, Carlos Pérez-González, D Bonn, D Gonzalez-Rodriguez, D Oriola, D Sarrió, DK Vig, DT Tambe, DT Tambe, E Bazellières, Elsa Bazellieres, F Jülicher, G Beaune, G Beaune, H Morita, I Muhamed, I Rodriguez-Hernandez, J Notbohm, J Paredes, J Prost, Jaume Casademunt, JL Ouderkirk, K Kruse, KA Paschos, L Casares, M Behrndt, M Deforet, Manuel Gómez-González, MC Marchetti, MH Köpf, O Chepizhko, P Campinho, P Friedl, P Gennes de, P Lee, P Lee, P Lu, PL Ryan, Ricard Alert, S Banerjee, S Douezan, S Douezan, S Douezan, S Garcia, S Kaliman, S Yabunaka, T Lecuit, TB Saw, Tomasz Kolodziej, TV Stirbat, US Schwarz, X Serra-Picamal, X Trepat, Xavier Trepat   +64 more
core   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Effects of electro-mechanical uncouplers, hormonal stimulation and pacing rate on the stability and function of cultured rabbit myocardial slices

Frontiers in Bioengineering and Biotechnology
Introduction: Recent advances have enabled organotypic culture of beating human myocardial slices that are stable for weeks. However, human myocardial samples are rare, exhibit high variability and frequently originate from diseased hearts.
V. Baron, S. T. Sommer, D. J. Fiegle, A.-K. M. Pfeuffer, R. Peyronnet, R. Peyronnet, T. Volk, T. Seidel   +7 more
doaj   +1 more source

Condensation tendency and planar isotropic actin gradient induce radial alignment in confined monolayers

eLife, 2021
A monolayer of highly motile cells can establish long-range orientational order, which can be explained by hydrodynamic theory of active gels and fluids.
Tianfa Xie, Sarah R St Pierre, Nonthakorn Olaranont, Lauren E Brown, Min Wu, Yubing Sun   +5 more
doaj   +1 more source