Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang +4 more
wiley +1 more source
The moderating role of the case-mix index in the relationship between medical staff allocation and average cost per inpatient visit. [PDF]
Xiong C, Xia Y, Xu S, Xiao J.
europepmc +1 more source
Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun +5 more
wiley +1 more source
Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma +11 more
wiley +1 more source
Epiphytic bacteria from Tacinga inamoena (K. Schum.) N.P. Taylor & Stuppy improve plant growth in cucumber seedlings. [PDF]
Pereira EJ +3 more
europepmc +1 more source
Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu +15 more
wiley +1 more source
Response to the Comment on "Effect of Modular Training on Self-Management, Disease, and Treatment Adaptation in Individuals With Hypertension". [PDF]
Keşer E, Atik D, Yüce UÖ.
europepmc +1 more source
Determination and Application of a New Drought Resistant Control Water Level for Multi-Reservoir Systems Based on Water Resource Allocation Model [PDF]
Yaping cheng +4 more
openalex +1 more source
A biotin‐modified artificial insertion peptide functionalized three‐dimensional high‐curvature‐TiO2 nano‐interface was engineered in a microfluidic chip to improve the isolation efficiency of small extracellular vesicles (sEVs). This chip balanced affinity, releasability, and extendibility, enabling high‐throughput recovery of sEVs for downstream ...
Le Wang +7 more
wiley +1 more source

