Results 41 to 50 of about 10,303,138 (298)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Contingency Plan for the Emergency Allocation of Motor Gasoline into Texas Hurricane Alert Areas

open access: yes, 1979
117 pagesDuring periods of reduced supplies of motor gasoline, inadequate volumes may exist for emergency evacuation depending upon the magnitude of the shortfall and local supply situations. To insure the flexibility needed to provide a quick and proper
Texas State Office of Petroleum Allocation
core   +1 more source

Dynamic bandwidth allocation in ATM networks [PDF]

open access: yes, 2002
Includes bibliographical references.This thesis investigates bandwidth allocation methodologies to transport new emerging bursty traffic types in ATM networks.
Ashibani, Majdi Ali Atoomi
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Trim Strategy, Control Model, and Flight Dynamics Characteristics of Canard Rotor/Wing Aircraft in Transition Mode

open access: yesIEEE Access, 2019
The transition mode of canard rotor/wing (CRW) aircraft is complex and important. During the transition flight, components that generate lift are transferred from one to another, in addition, the redundancy of control system may induce control conflict ...
Honggang Gao   +3 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Control Allocation for an Over-Actuated Aircraft Based on Within-Visual-Range Air Combat Agility

open access: yesIEEE Access, 2018
The control allocation problems of an over-actuated aircraft are studied to fully utilize the within-visual-range (WVR) air combat agility. By analyzing the agility requirements of modern WVR air combat, a control effector superiority evaluating method ...
Yan Liu, Zhenghong Gao, Chongyang Shang
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

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