Results 111 to 120 of about 13,466 (296)

Modelado, simulación y control lineal para multicópteros [PDF]

open access: yes, 2019
En años recientes la evolución de la propulsión eléctrica ha comenzado a impactar en el desarrollo de la aviación liviana. Los multicópteros no tripulados de pequeño tamaño ya se han consolidado como plataformas de observación aérea en una multiplicidad ...
Zumarraga, Augusto   +1 more
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Modelado y control de sistemas no-lineales

open access: yes, 1993
Fil: Calvo, Rafael A.. Universidad Nacional de Rosario - CONICET. Instituto de Física de Rosario (IFIR).
Calvo, Rafael A.   +2 more
openaire   +2 more sources

Analisis no lineal torre de control aéreo

open access: yes
En el presente trabajo se compara el Análisis Dinámico Elástico Espectral (LDP) de una Torre de Control Aéreo construida en concreto reforzado, con los Análisis No Lineal Estático (NSP) y el Análisis No Lineal Contra el Tiempo (NDP); se aclaran los ...
Alfonso González, Germán Camilo
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Un nuevo método de control PI no lineal robusto

open access: yes, 2017
This paper presents a robust nonlinear PI control. The dynamic balance of tradeoff between performance and robustness inside of a robustness region and to guarantee a balance's trayectory that minimize the integrated absolute error are the objectives of ...
Ramírez Mendoza, Mercedes   +2 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Aproximación al control de la fase de vuelo de un dirigible

open access: yesCiencia e Ingeniería Neogranadina, 2008
El presente trabajo tiene por objetivo el modelo dinámico de un dirigible (como Karma y UrAn), y la elaboración de un conjunto de leyes de control de velocidad, altitud y dirección cuando el dirigible se desplaza en la fase de vuelo crucero. La primera
Leonardo Solaque Guzmán   +1 more
doaj  

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