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Studies on conotoxins of Conus betulinus.
Journal of natural toxins, 2000The biological activity and toxicity of crude venom from Conus betulinus, which was collected from the South China Sea, were studied. The venom shows Ach receptor activity, K+ current effect, and low toxicity. Four peptide components, named BeTXIa, BeTXIb, BeTXIIa, and BeTXIIb, were purified by gel-filtration with Sephadex followed by HPLC, and finally
J S, Chen +4 more
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Purification and characterization of a new conotoxin from the venom of Conus betulinus
2005Marine snails belonging to the genus Conus are venomous predators that have developed a unique biochemical strategy for envenoming their prey. Their venom contains a number of small peptides ranging in size from ~13 to 30 amino acid residues. The structures and mode of action of many peptides from Conus venom have been elucidated [ 1, 2].
Chong-Xu Fan +8 more
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Conus betulinus Transcriptome or Gene expression
2015The venom of predatory marine cone snails mainly contains a diverse array of unique bioactive peptides commonly referred to as conopeptides or conotoxins. These peptides have proven to be valuable pharmacological probes and potential drugs because of their high specificity and affinity to important ion channels, receptors and transporters of the ...
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Journal of Proteome Research
The venom of cone snails, a potent weapon for predation and defense, contains diverse bioactive peptides (known as conopeptides, or conotoxins) that target various ion channels and receptors, offering potential as pharmacological tools or therapeutics.
Yan Wang +5 more
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The venom of cone snails, a potent weapon for predation and defense, contains diverse bioactive peptides (known as conopeptides, or conotoxins) that target various ion channels and receptors, offering potential as pharmacological tools or therapeutics.
Yan Wang +5 more
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Preliminary studies on venom of a marine snail Conus betulinus
2005Ji-Sheng Chen +9 more
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Isolation and Characterization of Conotoxin bt5a from
Chinese Journal of Natural Medicines, 2010Ji-Sheng Chen
exaly
Novel O-superfamily Conotoxins Identified by cDNA Cloning From Three Vermivorous Conus Species
Chemical Biology and Drug Design, 2006Dongting Zhangsun +2 more
exaly