Results 61 to 70 of about 3,522,210 (286)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

QUALITY EVALUATION OF FRESH RUTABAGA [PDF]

open access: yesТехника и технология пищевых производств, 2017
The diet of a modern man should contain fruits and vegetables as producers of physiologically active substances. However, rutabaga - primordial Russian vegetable - has been unfairly forgotten in the range of this product group.
Glebova S.Y., Golub O.V.
doaj   +1 more source

ADB–OECD Study on Enhancing Financial Accessibility for SMEs: Lessons from Recent Crises [PDF]

open access: yes, 2014
During the era of global financial uncertainty, stable access to appropriate funding sources has been much harder for small and medium-sized enterprises (SMEs).
Asian Development Bank   +1 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The Impact of CSI and Power Allocation on Relay Channel Capacity and Cooperation Strategies

open access: yes, 2007
Capacity gains from transmitter and receiver cooperation are compared in a relay network where the cooperating nodes are close together. Under quasi-static phase fading, when all nodes have equal average transmit power along with full channel state ...
Goldsmith, Andrea J., Ng, Chris T. K.
core   +2 more sources

Oil and international cooperation [PDF]

open access: yes, 2015
The more that states depend on oil exports, the less cooperative they become: they grow less likely to join intergovernmental organizations, to accept the compulsory jurisdiction of international judicial bodies, and to agree to binding arbitration for ...
Ross, ML, Voeten, E
core   +2 more sources

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Union-Management Cooperation: A Passing Fad or Permanent Change? [PDF]

open access: yes, 1984
[Excerpt] Union-management cooperation is not a passing fad. It is not a new, or even a recent, development on the American labor relations scene. Nonetheless, interest in this subject has been growing.
Gray, Lois S.
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Forming Process, Pattern and The Need for Intergovernmental Management in Indonesia [PDF]

open access: yes, 2012
Cooperation among neighbouring region is commonly termed regional cooperation. Inter-region cooperation in the study of public administration is categorized as public management especially intergovernmental management.
Warsono, Hardi
core  

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