Results 41 to 50 of about 5,911 (153)

The scale matters: A review on stimuli‐responsive microrobots categorized by scale for biomedical applications

Responsive Materials, EarlyView.
We systematically summarize how each scale dictates fundamental choices in design feature, manufacturing technology, driving mechanism, and control strategy, which are inherently governed by scale‐dominated physical principles. Furthermore, the application of scale‐determined operation modes of microrobots across different stages of medical ...
Hang Yin, Yujing Li, Guanghao Wu, Yubing Guo   +3 more
wiley   +1 more source

Segregation of COPI-rich and anterograde-cargo-rich domains in endoplasmic-reticulum-to-Golgi transport complexes [PDF]

, 1927
Membrane traffic between the endoplasmic reticulum (ER) and the Golgi complex is regulated by two vesicular coat complexes, COPII and COPI. COPII has been implicated in the selective packaging of anterograde cargo into coated transport vesicles budding ...
Shima, David T., Scales, Suzie J., Kreis, Thomas E., Pepperkok, Rainer   +3 more
core   +1 more source

Adaptation of the invasive pest Drosophila suzukii to a specialized nutritional niche

Insect Science, EarlyView.
Unlike most Drosophila larvae that feed on spoiled food, Drosophila suzukii larvae thrive on ripening fruits and consequently face a low‐protein, high‐carbohydrate nutritional challenge. Comparisons of growth among D. suzukii, D. biarmipes, and D. melanogaster larvae across diets with varying protein‐to‐carbohydrate ratios demonstrate that D.
Yan Hou, Ying Zhen
wiley   +1 more source

Reconstituting ring-rafts in bud-mimicking topography of model membranes. [PDF]

, 2014
During vesicular trafficking and release of enveloped viruses, the budding and fission processes dynamically remodel the donor cell membrane in a protein- or a lipid-mediated manner.
Jeon, Noo Li, Jordan, Luke R, Lee, Byoungho, Lee, In-Ho, Lee, Sin-Doo, Oh, Sang-Hyun, Oh, Soojung, Parikh, Atul N, Park, Seung Chul, Ryu, Yong-Sang, Suh, Jeng-Hun, Wittenberg, Nathan J   +11 more
core   +2 more sources

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, Volume 14, Issue 4, Page 978-991, May 2026.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

The ArfGAP Glo3 is required for the generation of COPI vesicles [PDF]

, 2004
The small GTPase Arf and coatomer (COPI) are required for the generation of retrograde transport vesicles. Arf activity is regulated by guanine exchange factors (ArfGEF) and GTPase-activating proteins (ArfGAPs).
Lewis, S. M., Poon, P. P., Singer, R. A., Johnston, G. C., Spang, A.   +4 more
core   +1 more source

Attenuated Bacteria‐Based Tumor Therapy: Clinical Application Risks, Marketing Approval Restrictions, and Coping Strategies

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This review comprehensively overviews attenuated bacteria‐based tumor therapy, highlighting key methodologies and recent progress. It examines strategies for enhancing safety, stabilizing efficacy, optimizing manufacturing, and navigating regulatory pathways.
Yucheng Liu, Junhong Yao, Jiaxin Deng, Minjie Zhou, Kaiyue Shen, Shishuo Sun, Xiaoge Gao, Qing Zhang, Haiheng Xu   +8 more
wiley   +1 more source

Physiological Functions of the COPI Complex in Higher Plants [PDF]

COPI vesicles are essential to the retrograde transport of proteins in the early secretory pathway. The COPI coatomer complex consists of seven subunits, termed alpha-, beta-, beta'-, gamma-, delta-, epsilon-, and zeta-COP, in yeast and mammals ...
Ahn, HK, Hwang, I, Kang, YW, Lim, HM, Pai, HS   +4 more
core   +1 more source

The cargo receptors Surf4, endoplasmic reticulum-golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi [PDF]

, 2008
Rapidly cycling proteins of the early secretory pathway can operate as cargo receptors. Known cargo receptors are abundant proteins, but it remains mysterious why their inactivation leads to rather limited secretion phenotypes.
Sandra Mitrovic, Houchaima Ben-Tekaya, Eva Koegler, Jean Gruenberg, Hans-Peter Hauri, Benjamin Glick, Andersson H., Appenzeller-Herzog C., Appenzeller C., Aridor M., Aridor M., Barr F. A., Barr F. A., Barr F. A., Barroso M., Belden W. J., Ben-Tekaya H., Bethune J., Bethune J., Blum R., Bonifacino J. S., Bremser M., Breuza L., Caldwell S. R., Cosson P., Denzel A., Diao A., Dominguez M., Emery G., Emery G., Fiedler K., Guo Y., Harlow E., Hauri H. P., Hunte C., Itin C., Jackson M. R., Jenne N., Kaiser C., Klausner R. D., Klumperman J., Lavoie C., Lippincott-Schwartz J., Majoul I., Muniz M., Nakamura N., Nakamura N., Nelson D. S., Nichols W. C., Nyfeler B., Nyfeler B., Otte S., Presley J. F., Puthenveedu M. A., Reeves J. E., Rojo M., Rothman J. E., Scales S. J., Schimmoller F., Schweizer A., Shugrue C. A., Sohda M., Sohn K., Stamnes M. A., Stauber T., Storrie B., Suga K., Sutterlin C., Taguchi T., Teasdale R. D., Vetrivel K. S., Vollenweider F., Zeuschner D., Zhang B.   +73 more
core   +1 more source

Cutting edge strategies for diabetic wound care: Nanotechnology, bioengineering, and beyond

BMEMat, Volume 4, Issue 1, March 2026.
Graphical abstract illustrates the challenges in diabetic wound healing, covering pathophysiology, formulation hurdles, and emerging therapeutic strategies. It highlights the role of hyperglycemia, formulation complexities, and advanced technologies like bioprinting and AI in improving diabetic wound management. Abstract Diabetic wounds affect millions
Usama Ahmad, Wan Nurhidayah Wan Hanaffi, Anas Islam, Aimen Salman, Mohd Muazzam Khan, Faiyaz Shakeel, Qiang Cai, Xiaojun Cai, Quazi T. H. Shubhra   +8 more
wiley   +1 more source