Results 41 to 50 of about 16,152 (159)

Cutting edge strategies for diabetic wound care: Nanotechnology, bioengineering, and beyond

BMEMat, EarlyView.
Graphical abstract illustrates the challenges in diabetic wound healing, covering pathophysiology, formulation hurdles, and emerging therapeutic strategies. It highlights the role of hyperglycemia, formulation complexities, and advanced technologies like bioprinting and AI in improving diabetic wound management. Abstract Diabetic wounds affect millions
Usama Ahmad, Wan Nurhidayah Wan Hanaffi, Anas Islam, Aimen Salman, Mohd Muazzam Khan, Faiyaz Shakeel, Qiang Cai, Xiaojun Cai, Quazi T. H. Shubhra   +8 more
wiley   +1 more source

Functional dissection of COP-I subunits in the biogenesis of multivesicular endosomes [PDF]

, 1997
In the present paper, we show that transport from early to late endosomes is inhibited at the restrictive temperature in a mutant CHO cell line (ldlF) with a ts-defect in epsilon coatomer protein (epsilon COP), although internalization and recycling ...
Aniento, Aniento, Besterman, Bomsel, Bradford, Brown, Chavrier, Clague, Cosson, Diment, Dunn, Fiedler, Futter, Geuze, Gorvel, Griffiths, Gruenberg, Gruenberg, Gruenberg, Gruenberg, Guo, Guo, Harder, Hobbie, Kornfeld, Koval, Kreis, Kreis, Letourneur, Lowe, Ludwig, Mellman, Mellman, Mu, Orci, Ostermann, Pagano, Parton, Parton, Pearse, Pelham, Pepperkok, Robinson, Rojo, Sipe, Sohn, Tooze, Trowbridge, van Deurs, Wada, Whitney, Yamashiro, Zerial   +52 more
core   +3 more sources

Proteomic and Lipidomic Profiling of Immune Cell‐Derived Subpopulations of Extracellular Vesicles

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are heterogeneous and play important roles in intercellular communication, contributing to physiological and pathological processes. Since few markers currently exist to differentiate subtypes of EVs, this study aimed to determine proteomic and lipidomic differences among four EV subpopulations. Large and small EVs
Anna Lischnig, Nasibeh Karimi, Per Larsson, Karin Ekström, Rossella Crescitelli, Anna‐Carin Olin, Cecilia Lässer   +6 more
wiley   +1 more source

Adaptation of the invasive pest Drosophila suzukii to a specialized nutritional niche

Insect Science, EarlyView.
Unlike most Drosophila larvae that feed on spoiled food, Drosophila suzukii larvae thrive on ripening fruits and consequently face a low‐protein, high‐carbohydrate nutritional challenge. Comparisons of growth among D. suzukii, D. biarmipes, and D. melanogaster larvae across diets with varying protein‐to‐carbohydrate ratios demonstrate that D.
Yan Hou, Ying Zhen
wiley   +1 more source

The COP II adaptor protein TMED7 is required to initiate and mediate the delivery of TLR4 to the plasma membrane. [PDF]

, 2014
Toll-like receptor 4 (TLR4), the receptor for the bacterial product endotoxin, is subject to multiple points of regulation at the levels of signaling, biogenesis, and trafficking.
Bryant, Clare E, Gay, Nicholas J, Liaunardy-Jopeace, Ardiyanto   +2 more
core   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

Identification of a 200-kD, brefeldin-sensitive protein on Golgi membranes [PDF]

, 1992
A mAb AD7, raised against canine liver Golgi membranes, recognizes a novel, 200-kD protein (p200) which is found in a wide variety of cultured cell lines.
Burke, B., Doherty, J., Matlin, K. S., McMorrow, I., Narula, N., Plopper, G., Stow, J. L.   +6 more
core   +1 more source

Defender or accomplice? Dual roles of plant vesicle trafficking in restricting and enabling geminiviral systemic infection

New Phytologist, EarlyView.
Summary The vesicle trafficking system enables multidirectional cargo fluxes between endomembrane compartments. However, vesicle trafficking plays dual roles during pathogen infections. In plants, it mediates autophagic immune responses but can also be hijacked by pathogens to facilitate successful infections.
Pepe Cana‐Quijada, Pablo Morales‐Martínez, Tábata Rosas‐Díaz, Jessica Pérez‐Sancho, Tamara Jiménez‐Góngora, José Antonio Navarro, Rosa Lozano‐Durán, Araceli G. Castillo, Vicente Pallás, Eduardo R. Bejarano   +9 more
wiley   +1 more source

Trafficking of the human Na+/H+ antiporter NHA2 to the plasma membrane requires cornichon COPII cargo receptors

Protein Science, Volume 35, Issue 3, March 2026.
Abstract A key prerequisite of transporter proteins' function is their trafficking to the target cellular membranes where they fulfill distinct physiological roles. Cornichon proteins (CNIH/Erv14) represent a highly conserved family of coat protein complex II (COPII)‐coated vesicle cargo receptors that facilitate the exit of numerous transporters from ...
Karolína Kacovská, Klára Papoušková, Gal Masrati, Paul Rosas‐Santiago, Tereza Przeczková, Veronika Žárská, Nir Ben‐Tal, Olga Zimmermannová   +7 more
wiley   +1 more source

Assembly and disassembly of the Golgi Complex: two prodesses arranged in a cis to trans direction [PDF]

, 1992
We have studied the disassembly and assembly of two morphologically and functionally distinct parts of the Golgi complex, the cis/middle and trans cisterna/trans network compartments.
Alcalde, José, Bonay, Pedro, Roa, Ana, Sandoval, Ignacio V., Vilaró, Senén, 1956-2005   +4 more
core   +2 more sources