Results 41 to 50 of about 5,935 (149)

The scale matters: A review on stimuli‐responsive microrobots categorized by scale for biomedical applications

Responsive Materials, EarlyView.
We systematically summarize how each scale dictates fundamental choices in design feature, manufacturing technology, driving mechanism, and control strategy, which are inherently governed by scale‐dominated physical principles. Furthermore, the application of scale‐determined operation modes of microrobots across different stages of medical ...
Hang Yin, Yujing Li, Guanghao Wu, Yubing Guo   +3 more
wiley   +1 more source

The COP II adaptor protein TMED7 is required to initiate and mediate the delivery of TLR4 to the plasma membrane. [PDF]

, 2014
Toll-like receptor 4 (TLR4), the receptor for the bacterial product endotoxin, is subject to multiple points of regulation at the levels of signaling, biogenesis, and trafficking.
Bryant, Clare E, Gay, Nicholas J, Liaunardy-Jopeace, Ardiyanto   +2 more
core   +1 more source

Adaptation of the invasive pest Drosophila suzukii to a specialized nutritional niche

Insect Science, EarlyView.
Unlike most Drosophila larvae that feed on spoiled food, Drosophila suzukii larvae thrive on ripening fruits and consequently face a low‐protein, high‐carbohydrate nutritional challenge. Comparisons of growth among D. suzukii, D. biarmipes, and D. melanogaster larvae across diets with varying protein‐to‐carbohydrate ratios demonstrate that D.
Yan Hou, Ying Zhen
wiley   +1 more source

Rab8, a small GTPase involved in vesicular traffic between the TGN and the basolateral plasma membrane [PDF]

, 1993
Small GTP-binding proteins of the rab family have been implicated as regulators of membrane traffic along the biosynthetic and endocytic pathways in eukaryotic cells.
Huber, L. A., Parton, R. G., Pimplikar, S., Simons, K., Virta, H., Zerial, M.   +5 more
core   +2 more sources

Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents

Chemistry – A European Journal, Volume 32, Issue 17, 5 May 2026.
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley   +1 more source

Nanomaterial‐Mediated Near‐Infrared Photothermal Neuromodulation for Neurologic Disorders

Advanced NanoBiomed Research, Volume 6, Issue 5, May 2026.
This review summarizes how near‐infrared light activates photothermal nanomaterials to enable noninvasive neuromodulation with high spatiotemporal precision. It elucidates the underlying mechanisms, explores targeted therapeutic applications for neurological disorders, discusses integration with optogenetics and biosensors, and addresses future ...
Ting‐Ting Zeng, Yu‐Ge Wang, Ya‐Bing Zhang, Yuan‐Xin Bai, Si‐Tong Lin, Ting‐Ting Zhu, Yan‐Bo Zhou, Wei‐Tong Pan, Pan‐Miao Liu, Jian‐Jun Yang   +9 more
wiley   +1 more source

Proteomic and Super‐Resolution Analyses of Murine Brown Adipocyte‐Derived Extracellular Vesicles

Journal of Extracellular Biology, Volume 5, Issue 5, May 2026.
Graphical Abstract ABSTRACT Thermogenic brown adipocytes (BAs) are not only an energy sink but also regulate systemic metabolic health through secreted factors and extracellular vesicles (EVs). Here, we investigate the baseline profiles BA‐EVs and how cold‐induced thermogenesis alters the proteome of BA‐EVs.
Menchus Quan, Yi‐Kai Liu, Maryam Mahmoodi, Muhammad Asif, Madeline Kay, Yongjie Yang, Fang Huang, Weiguo Andy Tao, Shihuan Kuang   +8 more
wiley   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, Volume 14, Issue 4, Page 978-991, May 2026.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

Functional dissection of COP-I subunits in the biogenesis of multivesicular endosomes [PDF]

, 1997
In the present paper, we show that transport from early to late endosomes is inhibited at the restrictive temperature in a mutant CHO cell line (ldlF) with a ts-defect in epsilon coatomer protein (epsilon COP), although internalization and recycling ...
Aniento, Aniento, Besterman, Bomsel, Bradford, Brown, Chavrier, Clague, Cosson, Diment, Dunn, Fiedler, Futter, Geuze, Gorvel, Griffiths, Gruenberg, Gruenberg, Gruenberg, Gruenberg, Guo, Guo, Harder, Hobbie, Kornfeld, Koval, Kreis, Kreis, Letourneur, Lowe, Ludwig, Mellman, Mellman, Mu, Orci, Ostermann, Pagano, Parton, Parton, Pearse, Pelham, Pepperkok, Robinson, Rojo, Sipe, Sohn, Tooze, Trowbridge, van Deurs, Wada, Whitney, Yamashiro, Zerial   +52 more
core   +3 more sources

Co‐Culture Systems to Study Epithelial‐Immune Interactions During SARS‐CoV‐2 Infection

Current Protocols, Volume 6, Issue 4, April 2026.
Abstract Robust inflammatory responses to viral infection are mediated by immune cell populations, including monocytes and dendritic cells. However, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) does not replicate efficiently in these cell types and instead preferentially infects epithelial cell subsets in the airway.
Scott H. Randell, Katherine C. Barnett
wiley   +1 more source