Results 11 to 20 of about 453,081 (334)
No evidence for additional systemic eosinophil mobilization during exacerbations in patients with COPD and chronic bronchitis but no allergy [PDF]
BackgroundThere is published evidence that a modest increase in blood eosinophils during stable COPD indicates future risk for exacerbations and a potential utility of inhaled corticosteroids. This has been perceived as an argument for targeting systemic
Anders Andersson+8 more
doaj +2 more sources
Developing a patient-driven chronic obstructive pulmonary disease (COPD) research agenda in the U.S.
Plain English summary The COPD Patient-Powered Research Network (PPRN) asked adults with COPD and their caregivers to suggest areas for future research on COPD.
Inga Gruß+7 more
doaj +1 more source
The relation between age and airway epithelial barrier function
Background The prevalence of age-associated diseases, such as chronic obstructive pulmonary disease (COPD), is increasing as the average life expectancy increases around the world.
M. de Vries+9 more
doaj +1 more source
Herpes zoster (HZ) is common in older adults with conditions such as chronic obstructive pulmonary disease (COPD). Effective prevention is available through vaccination, but HZ vaccine uptake remains incomplete. Using an online survey of people with self-
Barbara P. Yawn+6 more
doaj +1 more source
T cells suppress memory-dependent rapid mucous cell metaplasia in mouse airways
Background Airway epithelial cells (AECs) are crucial for mucosal and adaptive immunity but whether these cells respond in a memory-dependent manner is poorly studied.
Hitendra S. Chand+3 more
doaj +1 more source
Addiction to tobacco smoking and vaping
The tobacco epidemic has been one of the biggest public health threats, and smoking is one of the world’s largest preventable causes of premature death. An estimated 15.4% of all deaths in the world are attributable to tobacco smoking. The present review
Andrea Hernández-Pérez+7 more
doaj +1 more source
Lung macrophages drive mucus production and steroid-resistant inflammation in chronic bronchitis
Background Patients with chronic obstructive pulmonary disease (COPD) frequently suffer from chronic bronchitis (CB) and display steroid-resistant inflammation with increased sputum neutrophils and macrophages. Recently, a causal link between mucus hyper-
Kristina Andelid+6 more
doaj +1 more source
Epithelial senescence in idiopathic pulmonary fibrosis is propagated by small extracellular vesicles
Background Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that affects 3 million people worldwide. Senescence and small extracellular vesicles (sEVs) have been implicated in the pathogenesis of IPF, although how sEVs promote disease ...
Sabha Asghar+7 more
doaj +1 more source
Dear Editor, We read with great interest the paper by Jones et al 1 about the prevalence, clinical correlates and response to pulmonary rehabilitation of sarcopenia in COPD. We believe that authors have meritoriously focused their attention on a highly relevant topic, which is the skeletal muscle decline in patients with COPD. Sarcopenia represents a
Matteo Cesari+3 more
openaire +3 more sources