Results 91 to 100 of about 28,053 (261)

Pancreatic beta cell ER export in health and diabetes

Frontiers in Endocrinology, 2023
In the secretory pathway of the pancreatic beta cell, proinsulin and other secretory granule proteins are first produced in the endoplasmic reticulum (ER). Beta cell ER homeostasis is vital for normal beta cell functions and is maintained by the delicate
Cesar Barrabi, Kezhong Zhang, Ming Liu, Xuequn Chen   +3 more
doaj   +1 more source

Rsp5 Ubiquitin Ligase Is Required for Protein Trafficking in Saccharomyces cerevisiae COPI Mutants [PDF]

, 2012
Retrograde trafficking from the Golgi to the endoplasmic reticulum (ER) depends on the formation of vesicles coated with the multiprotein complex COPI.
Jarmoszewicz, Katarzyna, Kaminska, Joanna, Riezman, Howard, Łukasiak, Katarzyna   +3 more
core   +4 more sources

When Aid Comes With Strings: Donor Power and Everyday Anti‐Trafficking Work in Moldova

International Migration, Volume 64, Issue 2, April 2026.
ABSTRACT Anti‐trafficking governance in Moldova unfolds far from the conference rooms where global priorities are set. Drawing on ethnographically informed research and 15 interviews with frontline practitioners, this article shows how donor agendas shape the daily realities of anti‐trafficking work, not only through funding, but through the softer ...
Ludmila Bogdan
wiley   +1 more source

Cauzele genetice asociate accidentului vascular cerebral ischemic la copii.

Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale, 2020
Introducere. Accidentul vascular cerebral ischemic (AVCI) reprezintă o boală rară la copii și adolescenți, deseori subestimată, cu un impact major asupra morbidității și mortalității.
Mariana Sprincean, Svetlana Hadjiu, Cornelia Călcîi, Elena Halabudenco, Nadejda Lupuşor, Ninel Revenco, Stanislav Groppa   +6 more
doaj  

An ancestral secretory apparatus in the protozoan parasite Giardia intestinalis [PDF]

, 2003
The protozoan parasite Giardia intestinalis belongs to one of the earliest diverged eukaryotic lineages. This is also reflected in a simple intracellular organization, as Giardia lacks common subcellular compartments such as mitochondria, peroxisomes ...
Hehl, Adrian B., Knopf, Lea G., Li, Yajie, Marti, Matthias, Müller, Norbert, Regös, Attila, Schraner, Elisabeth M., Wild, Peter   +7 more
core   +1 more source

COPII cage assembly factor Sec13 integrates information flow regulating endomembrane function in response to human variation

Scientific Reports
How information flow is coordinated for managing transit of 1/3 of the genome through endomembrane pathways by the coat complex II (COPII) system in response to human variation remains an enigma.
F. Anglès, Vijay Gupta, Chao Wang, William E. Balch   +3 more
semanticscholar   +1 more source

INDICELE INTIMĂ MEDIE CAROTIDIAN LA COPIII OBEZI NĂSCUŢI CU GREUTATE MICĂ PENTRU VÂRSTA GESTAŢIONALĂ VERSUS CEI NĂSCUŢI CU GREUTATE NORMALĂ PENTRU VÂRSTA GESTAŢIONALĂ [PDF]

Romanian Journal of Pediatrics, 2014
Indicele intimǎ medie carotidian (IMc) este un cunoscut marker subclinic pentru aterosclerozǎ. Fenomenul de recuperare nutriţionalǎ la copiii nǎscuţi mici pentru vârsta gestaţionalǎ (SGA) a fost asociat cu obezitate precoce şi cu riscul dezvoltǎrii ...
Ramona Stroescu, Ioana Micle, Teofana Bizerea, Monica Mărăzan, Maria Puiu, Gabriela Doroş, Otilia Mărginean   +6 more
doaj   +1 more source

COPII vesicles contribute to autophagosomal membranes

Journal of Cell Biology, 2019
A hallmark of autophagy is the de novo formation of double-membrane vesicles called autophagosomes, which sequester various cellular constituents for degradation in lysosomes or vacuoles. The membrane dynamics underlying the biogenesis of autophagosomes,
Takayuki Shima, Hiromi Kirisako, H. Nakatogawa   +2 more
semanticscholar   +1 more source

The endoplasmic reticulum in mitochondrial protein targeting: A neuronal perspective on organelle crosstalk

Protein Science, Volume 35, Issue 3, March 2026.
Abstract Neurons depend on tightly regulated spatial proteostasis to maintain function across their extended morphology. The endoplasmic reticulum (ER), traditionally known for its function in protein synthesis, folding, and trafficking, has long been recognized as a central platform for directing proteins to organelles of the secretory and endocytic ...
J. Tabitha Hees, Angelika B. Harbauer
wiley   +1 more source

SINDROM ADRENOGENITAL LA NOU-NĂSCUT [PDF]

Romanian Journal of Pediatrics, 2013
Deshidratarea acută severă la sugar poate să survină în contextul unor multiple cauze etiologice, cea mai frecventă fi ind gastroenterita acută. Rezistenţa la tratamentul de corecţie electrolitic şi acidobazic prin persistenţa hiponatremiei alături de ...
Alina Murgu, Cătălina Ionescu, F. Cristogel, Adriana Baltag, Cezarina Dragomirescu, Evelina Moraru   +5 more
doaj   +1 more source