Results 31 to 40 of about 75,676 (211)

CoQ₁₀Phytosomes Improve Cellular Ubiquinone Uptake in Skeletal Muscle Cells: An Ex Vivo Study Using CoQ₁₀-Enriched Low-Density Lipoproteins Obtained in a Randomized Crossover Study

Antioxidants, 2023
Coenzyme Q10 (CoQ10) bioavailability in vivo is limited due to its lipophilic nature. Moreover, a large body of evidence in the literature shows that muscle CoQ10 uptake is limited. In order to address cell specific differences in CoQ uptake, we compared
Fabio Marcheggiani, Patrick Orlando, Sonia Silvestri, Ilenia Cirilli, Antonella Riva, Giovanna Petrangolini, Francesca Orsini, Luca Tiano   +7 more
doaj   +1 more source

Mixing HOL and Coq in Dedukti (Extended Abstract)

, 2015
We use Dedukti as a logical framework for interoperability. We use automated tools to translate different developments made in HOL and in Coq to Dedukti, and we combine them to prove new results.
Assaf, Ali, Cauderlier, Raphaël
core   +4 more sources

Terminal semantics for codata types in intensional Martin-L\"of type theory [PDF]

, 2014
In this work, we study the notions of relative comonad and comodule over a relative comonad, and use these notions to give a terminal coalgebra semantics for the coinductive type families of streams and of infinite triangular matrices, respectively, in ...
Ahrens, Benedikt, Spadotti, Régis
core   +2 more sources

How plants synthesize coenzyme Q

Plant Communications, 2022
Coenzyme Q (CoQ) is a conserved redox-active lipid that has a wide distribution across the domains of life. CoQ plays a key role in the oxidative electron transfer chain and serves as a crucial antioxidant in cellular membranes.
Jing-Jing Xu, Mei Hu, Lei Yang, Xiao-Ya Chen   +3 more
doaj   +1 more source

Dependence of Brown Adipose Tissue Function on CD36-Mediated Coenzyme Q Uptake

Cell Reports, 2015
Brown adipose tissue (BAT) possesses the inherent ability to dissipate metabolic energy as heat through uncoupled mitochondrial respiration. An essential component of the mitochondrial electron transport chain is coenzyme Q (CoQ).
Courtney M. Anderson, Melissa Kazantzis, Jinshan Wang, Subramaniam Venkatraman, Renata L.S. Goncalves, Casey L. Quinlan, Ryan Ng, Martin Jastroch, Daniel I. Benjamin, Biao Nie, Candice Herber, An-Angela Ngoc Van, Michael J. Park, Dawee Yun, Karen Chan, Angela Yu, Peter Vuong, Maria Febbraio, Daniel K. Nomura, Joseph L. Napoli, Martin D. Brand, Andreas Stahl   +21 more
doaj   +1 more source

Cell survival from chemotherapy depends on NF-kappaB transcriptional up-regulation of coenzyme Q biosynthesis. [PDF]

PLoS ONE, 2009
BACKGROUND: Coenzyme Q (CoQ) is a lipophilic antioxidant that is synthesized by a mitochondrial complex integrated by at least ten nuclear encoded COQ gene products.
Gloria Brea-Calvo, Emilio Siendones, José A Sánchez-Alcázar, Rafael de Cabo, Plácido Navas   +4 more
doaj   +1 more source

L-Carnosine Stimulation of Coenzyme Q10 Biosynthesis Promotes Improved Mitochondrial Function and Decreases Hepatic Steatosis in Diabetic Conditions

Antioxidants, 2021
Mitochondrial dysfunction in type 2 diabetes leads to oxidative stress, which drives disease progression and diabetes complications. L-carnosine, an endogenous dipeptide, improves metabolic control, wound healing and kidney function in animal models of ...
Cheng Schwank-Xu, Elisabete Forsberg, Magnus Bentinger, Allan Zhao, Ishrath Ansurudeen, Gustav Dallner, Sergiu-Bogdan Catrina, Kerstin Brismar, Michael Tekle   +8 more
doaj   +1 more source

Proteolytic control of mitochondrial protein translocases. [PDF]

Protein Sci
Abstract Mitochondria are essential organelles that drive numerous cellular processes, including energy metabolism, ion homeostasis, and programmed cell death. This functional versatility relies on a highly dynamic proteome whose composition is continuously remodeled to meet changing cellular and environmental demands.
Kroczek L, Langer T.
europepmc   +2 more sources

A measurement of quality costs in industrial organizations

Cogent Business & Management, 2022
This paper aims to determine the level of awareness and implementation of measuring CoQ in MIEs in Yemen. In contrast, this study was based on the traditional CoQ Prevention—Appraisal—Failure (PAF) model.
Riyadh Y. Alsada, Yathish Kumar
doaj   +1 more source

Clinical syndromes associated with Coenzyme Q10 deficiency. [PDF]

, 2018
Primary Coenzyme Q deficiencies represent a group of rare conditions caused by mutations in one of the genes required in its biosynthetic pathway at the enzymatic or regulatory level.
Alc\ue1zar-Fabra, Maria, Brea-Calvo, Gloria, Trevisson, Eva   +2 more
core   +1 more source