Results 181 to 190 of about 15,951 (206)

Infantile encephalomyopathy and nephropathy with CoQ10 deficiency: A CoQ10-responsive condition

Neurology, 2005
Coenzyme Q10 (CoQ10) deficiency has been associated with various clinical phenotypes, including an infantile multisystem disorder. The authors report a 33-month-old boy who presented with corticosteroid-resistant nephrotic syndrome in whom progressive encephalomyopathy later developed. CoQ10 was decreased both in muscle and in fibroblasts.
SALVIATI, LEONARDO, SACCONI S, MURER L, ZACCHELLO G, FRANCESCHINI L, LAVERDA AM, BASSO, GIUSEPPE, QUINZII C, ANGELINI, CORRADO, HIRANO M, NAINI AB, NAVAS P, DIMAURO S, MONTINI G.   +13 more
openaire   +4 more sources

Evaluation of Antioxidative Activity between CoQ10-Nanostructured Lipid Carrier and CoQ10 Cosmetic

Applied Mechanics and Materials, 2011
Coenzyme Q10 (CoQ10) is a poorly water-soluble active ingredient with intrinsic chemical instability, but holds strongly antioxidative capacity. The CoQ10-NLC aqueous dispersion has been prepared, the antioxidative activity between CoQ10-NLC and CoQ10 cosmetic have been investigated, and several employed methods such as scavenging efficiency on DPPH ...
Jian Min Wang, Yan Li, Hong Xia Wang, Yun Long Yao, Hong Jing Zhou, Guang Yu Liu, Qiang Xia   +6 more
openaire   +1 more source

Anti‐inflammatory effects of CoQ10 and colorless carotenoids

Journal of Cosmetic Dermatology, 2006
SummaryBackground  CoQ10 (ubiquinone, coenzyme Q10) and carotenoids are popular antioxidants used in many skin care products to protect the skin from free radical damage.Aim  To evaluate the effects of CoQ10 and colorless carotenoids on the production of inflammatory mediators in human dermal fibroblasts treated with UV radiation (UVR) and to ...
Bryan, Fuller, Dustin, Smith, Amber, Howerton, Dale, Kern   +3 more
openaire   +2 more sources

Bioavailability of water-soluble CoQ10 in beagle dogs

Journal of Pharmaceutical and Biomedical Analysis, 2008
The bioavailability of a novel water-soluble inclusion complex of CoQ10, prepared in our laboratory was determined and compared with the bioavailability of commercially available oil-based form of CoQ10. Experimental work consisted of single dose comparative bioavailability study on seven beagle dogs, with a 14-day washout period between treatments ...
Mirko, Prosek, Janos, Butinar, Barbara, Lukanc, Maja Milivojevic, Fir, Luka, Milivojevic, Mitja, Krizman, Andrej, Smidovnik   +6 more
openaire   +2 more sources

Extracellular coenzyme Q10 (CoQ10) is reduced to ubiquinol-10 by intact Hep G2 cells independent of intracellular CoQ10 reduction

Archives of Biochemistry and Biophysics, 2019
Coenzyme Q10 (CoQ10) is an essential factor in the mitochondrial respiratory chain and is closely associated with ATP production in humans. It is known that orally administered CoQ10 in humans is rapidly reduced, and most is detected as a reduced form, ubiquinol-10 (CoQ10H2), in serum.
Takayuki, Takahashi, Yukitoshi, Mine, Tadashi, Okamoto   +2 more
openaire   +2 more sources

The role of CoQ10 in embryonic development

Journal of Assisted Reproduction and Genetics
Coenzyme Q10 (CoQ10) is a natural component widely present in the inner membrane of mitochondria. CoQ10 functions as a key cofactor for adenosine triphosphate (ATP) production and exhibits antioxidant properties in vivo. Mitochondria, as the energy supply center of cells, play a crucial role in germ cell maturation and embryonic development, a ...
Xueke He, Hao Chen, Minjun Liao, Xiaomei Zhao, Dawei Zhang, Miao Jiang, Zhisheng Jiang   +6 more
openaire   +2 more sources

Formation of CoQ10 reduced form by mixing CoQ10 oxidized form γCD complex and vitamin C in powder

Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2010
We have already reported the enhancement of the stability and bioavailability of coenzyme Q10 (CoQ10) oxidized form by γ-cyclodextrin (γCD) complexation. In a series of the studies, we investigated an easy and economical conversion of CoQ10 oxidized form to its reduced form in complex powder, using inexpensive vitamin C (VC) as the reductant.
Yukiko Uekaji, Daisuke Nakata, Hirokazu Shiga, Ayako Jo, Iwao Tachi, Hiroshi Fukumi, Akihito Urano, Keiji Terao   +7 more
openaire   +1 more source

Skin penetration of CoQ10 in the rat.

International journal of tissue reactions, 1988
Skin penetration of coenzyme Q10 (CoQ10) was investigated after topical treatment in the rat. The drug was suspended in olive oil and administered at two different concentrations. Coenzyme levels were found to be directly related to the concentrations employed and the contact time.
GIOVANNINI, LUCA, Bertelli AA, Scalori V, DELL'OSSO, LILIANA, Alessandrì MG, Mian M.   +5 more
openaire   +2 more sources

Benefits of CoQ10 supplementation in patients with SRNS due to primary CoQ10 deficiency

Nature Reviews Nephrology, 2022
openaire   +2 more sources

Breast cancer treatment with coenzyme Q10 (CoQ10)

Multidisciplinary Reviews
Coenzyme Q10 (CoQ10) was identified in the late 1950s, and its potential role in cancer therapy appeared in the early 1960s when decreasing CoQ10 levels were found in some cancer patients. Breast cancer is a serious global health issue, and novel treatments are being developed. Its treatment is being investigated.
Pratiksha V. Shende, Gaurav S. Mude, Abhishek G. Amipara   +2 more
openaire   +1 more source