Results 111 to 120 of about 5,519,513 (263)

Clinical outcomes of the PAUL® glaucoma implant for secondary glaucoma

Acta Ophthalmologica, EarlyView.
Abstract Purpose Secondary glaucoma encompasses a broad spectrum of disease entities arising from diverse ocular pathologies and is often refractory to conventional treatment. Glaucoma drainage devices (GDDs) have therefore become an important surgical option.
Carolin Deubel, Benjamin Aretz, Wolfgang Walz, Michael Petrak, Frank G. Holz, Raffael Liegl, Karl Mercieca, Constance Liegl   +7 more
wiley   +1 more source

Corneal endothelial cell‐matrix interactions in Fuchs corneal endothelial dystrophy

Acta Ophthalmologica, 2019
Abstract Fuchs endothelial corneal dystrophy (FECD) is characterized by progressive loss of corneal endothelial cells (CECs) and excessive deposition of extracellular matrix, resulting in Descemet's membrane thickening and formation of excrescences (guttae) on its posterior surface. The role of the endothelium being to keep the cornea
openaire   +1 more source

Optic nerve head blood flow autoregulation during isometric exercise in primary open‐angle glaucoma assessed by laser speckle flowgraphy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess optic nerve head blood flow (ONHBF) autoregulation in patients with early‐ to moderate‐stage primary open‐angle glaucoma (POAG) and age‐ and sex‐matched healthy controls using laser speckle flowgraphy (LSFG) and isometric handgrip exercise.
Theresa Lindner, Viktoria Pai, Patrick Janku, Nikolaus Hommer, Anton Hommer, Liudmyla Petric, Ulrich Graf, Leopold Schmetterer, Gerhard Garhöfer, Doreen Schmidl   +9 more
wiley   +1 more source

Therapy of corneal endothelial dysfunction with corneal endothelial cell-like cells derived from skin-derived precursors

, 2017
Corneal endothelial dysfunction occurs when corneal endothelial cells (CECs) are dramatically lost and eventually results in vision loss. Corneal transplantation is the only solution at present.
Xinyi Wu, Le Yang, Peng Sun, Liqun Du, Lin Shen, Canwei Zhang   +5 more
core   +1 more source

Outcomes of therapeutic penetrating keratoplasty and deep anterior lamellar keratoplasty in acanthamoeba keratitis: A systematic review and meta‐analysis

Acta Ophthalmologica, EarlyView.
Abstract While acanthamoeba keratitis (AK) is a sight‐threatening corneal infection, a thorough comparison of the outcomes of therapeutic penetrating keratoplasty (PK) and therapeutic deep anterior lamellar keratoplasty (DALK) is lacking. We aimed to compare clinical outcomes of PK and DALK in AK.
Gábor Tóth, Junbo Wang, Shanhe Liu, Shuailin Li, Szilárd Váncsa, Mátyás Paczkó, Tamás Kói, Péter Hegyi, Nóra Szentmáry   +8 more
wiley   +1 more source

Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density

Nature Communications, 2019
The corneal endothelium is crucial for proper vision. Here, Ivarsdottir et al. perform genome-wide association studies for various corneal endothelial cell measurements and find that an intergenic variant near ANAPC1 explains 24% of the variance of ...
Erna V. Ivarsdottir, Stefania Benonisdottir, Gudmar Thorleifsson, Patrick Sulem, Asmundur Oddsson, Unnur Styrkarsdottir, Snaedis Kristmundsdottir, Gudny A. Arnadottir, Gudmundur Thorgeirsson, Ingileif Jonsdottir, Gunnar M. Zoega, Unnur Thorsteinsdottir, Daniel F. Gudbjartsson, Fridbert Jonasson, Hilma Holm, Kari Stefansson   +15 more
doaj   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Corneal Endothelial Morphology and Thickness Changes in Patients with Gout

, 2019
Objectives:To investigate corneal endothelial cell density (ECD), morphology, and central corneal thickness (CCT) in patients with gout compared with healthy subjects.Materials and Methods:Fifty eyes of 50 gout patients and 50 eyes of 50 healthy subjects
Kadir Gökhan Atılgan, Mustafa Koç, Yasin Şakir Göker, Cemile Üçgül Atılgan, Kemal Tekin, Mehtap Çağlayan, Pınar Kösekahya   +6 more
core   +1 more source

Impact of COVID-19 on corneal endothelial density and morphology: a cross-sectional study in convalescent patients

Frontiers in Medicine
AimThis study aimed to investigate the effect of COVID-19 infection on corneal endothelial cell density and morphology, and to analyze the related factors.MethodsThis cross-sectional study included patients who underwent corneal endothelial examination ...
Ling Zhang, Wenjian Shi, Xiumei Guo, Runhua Lv, Huilin Guan, Feng Zheng, Yingying Gao   +6 more
doaj   +1 more source

Premium Intraocular Lens Selection in Patients With Glaucoma: A Clinical Review

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Glaucoma frequently coexists with cataract, but glaucomatous functional loss, ocular‐surface disease, anatomical abnormalities, and treatment‐related refractive variability may reduce tolerance of premium intraocular lenses. This narrative review critically appraises evidence relevant to lens selection in glaucoma. Central visual‐field status,
Zhihao Liu, Yajuan Zheng, Mingxuan Wang, Jing Zhao   +3 more
wiley   +1 more source