Results 131 to 140 of about 5,519,513 (263)

An Optimized Mechanical Peeling Protocol for Mouse Corneal Endothelium

Bioengineering
Corneal endothelium is a single layer of polygonal cells responsible for maintaining stromal dehydration and corneal transparency. Isolating corneal endothelium from murine models is exceptionally challenging without an established protocol, which ...
Zhenwei Song, Liujiang Song, Hua Mei
doaj   +1 more source

The TCF4 Gene Regulates Apoptosis of Corneal Endothelial Cells in Fuchs Endothelial Corneal Dystrophy

Investigative Ophthalmology & Visual Science
Fuchs endothelial corneal dystrophy (FECD) is a progressive corneal disorder characterized by excessive extracellular matrix (ECM) accumulation and corneal endothelial cell death. CTG trinucleotide repeat expansion in the transcription factor 4 (TCF4) gene represents the most significant genetic risk factor.
Nakagawa, Tatsuya, Honda, Tetsuro, Yuasa, Taichi, Nishiuchi, Go, Sato, Masakazu, Tokunaga, Ayumi, Nakahara, Makiko, Tourtas, Theofilos, Schlötzer-Schrehardt, Ursula, Kruse, Friedrich, Padmanabhan, Prema, Chatterjee, Amit, Sathe, Gajanan, Ghose, Vivek, Janakiraman, Narayanan, Blake, Derek J., Koizumi, Noriko, Elchuri, Sailaja, Okumura, Naoki   +18 more
openaire   +2 more sources

Analysis of corneal endothelial cell density and morphology after laser in situ keratomileusis using two types of femtosecond lasers

, 2012
Minoru Tomita,1,2,* George O Waring IV,3,4 Miyuki Watabe,1,* 1Shinagawa LASIK Center, Chiyoda-ku, Tokyo, Japan; 2Department of Ophthalmology, Wenzhou Medical College, Wenzhou, China; 3Medical University of South Carolina, Storm Eye Institute, Charleston,
Tomita M, Waring GO IV, Watabe M
core  

Interventional human ocular safety experiments for 222‐nm far‐ultraviolet‐C lamp irradiation

Photochemistry and Photobiology, Volume 101, Issue 2, Page 517-526, March/April 2025.
To directly assess the ocular safety of 222‐nm far‐ultraviolet‐C (UVC) irradiation in humans, five subjects were exposed to 222‐nm UVC at doses of 22, 50, and 75 mJ/cm2. The findings indicate that far‐UVC irradiation does not cause “clinically significant photokeratitis” or long‐term ocular damage, though it may induce temporary discomfort.
Kazunobu Sugihara, Sachiko Kaidzu, Masahiro Sasaki, Masaki Tanito   +3 more
wiley   +1 more source

Effects of Tobacco on Corneal Endothelial Cells – a Hospital-based Cross-sectional Study from Western Gujarat, India

Background The aim was to evaluate various detrimental effects of tobacco chewing and smoking on corneal endothelial cells and morphology, as tobacco causes various ocular conditions, including cataract, glaucoma, dry eye, optic neuropathy, age-related ...
Rutvi Sadatia, SAWAN CHUG, KRUNAL MODI, SONAL AGRAWAL   +3 more
core   +1 more source

Comparison of Corneal Endothelial Changes After a Single-Dose Injection of Bevacizumab or Ranibizumab

, 2013
Purpose: To compare the corneal endothelial changes after injection of a single-dose intravitreal bevacizumab or intravitreal ranibizumab. Material and Method: In this retrospective study, we evaluated 27 eyes of 27 patients with either diabetic ...
Tansu Gönen, Mustafa Yaşar, Fatih Horozoğlu   +2 more
core   +1 more source

Depth of DNA photodamage in human corneas exposed to 222 nm or 254 nm UV

Photochemistry and Photobiology, EarlyView.
Representative confocal 3D image of a section of a human cornea showing nuclei in blue (Hoechst 33342) and green, which was assigned to cells exhibiting Alexa555 conjugated to anti‐CPD antibody. The depth of photodamage was measured in Z‐stacks of the human corneal epithelium after exposure of the anterior surface to 50 or 100 mJ/cm2 at 222 or 254 nm ...
Manuela Buonanno, Istvan R. Boldogh, Raabia Hashmi, Camryn Petersen, David Welch, Theresa C. Swayne, David J. Brenner   +6 more
wiley   +1 more source

Human ocular‐discomfort‐free thresholds for 222 nm Far‐UVC irradiation: A prospective interventional study

Photochemistry and Photobiology, EarlyView.
Eye discomfort induced by 222 nm far‐UVC irradiation is significantly correlated with both irradiance and radiant exposure dose. The red circles indicate conditions with significant differences in the number of eye discomfort compared to the control group (blue circles), while the green circles indicate conditions with no difference from the control ...
Sachiko Kaidzu, Kazunobu Sugihara, Masaki Tanito   +2 more
wiley   +1 more source

Early oxidation‐related changes in aqueous humor following eye exposure to ultraviolet‐A radiation

Photochemistry and Photobiology, EarlyView.
UVA exposure induces early oxidative alterations in the aqueous humor, disrupting its antioxidant balance. Levels of ascorbic acid, reduced glutathione (GSH), and the GSH/GSSG ratio decrease, while oxidized glutathione (GSSG), S‐glutathionylated proteins (PSSG), and malondialdehyde (MDA), a lipid peroxidation by‐product, increase.
Corinne Zinflou, Patrick J. Rochette
wiley   +1 more source

Specular microscopy study on corneal endothelial cells after chemical injury.

, 2015
CCT = central corneal thickness; CECD = central endothelial cell density; CV = coefficient of variation; N/A = not availableSpecular microscopy study on corneal endothelial cells after chemical injury.
Joon Young Hyon (796902), Tae-young Chung (796904), Yun-Jung Oh (796903), Young Joo Shin (796905), Won Ryang Wee (729921), Jeong Won Kim (796906), Sang Ouk Choi (796900), Hyun Sun Jeon (796901)   +7 more
core   +1 more source