Results 151 to 160 of about 5,519,513 (263)

Therapies for Cardiovascular‐Kidney‐Liver‐Metabolic Syndrome: Reappraisal of Fibrates

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 10931-10949, December 2026.
ABSTRACT Cardiovascular disease, chronic kidney disease (CKD), type 2 diabetes mellitus (T2DM), obesity and metabolic dysfunction‐associated steatohepatitis (MASH) frequently coexist and share overlapping pathophysiology, forming the proposed cardiovascular‐kidney‐liver‐metabolic (CKLM) syndrome.
Virginia Anagnostopoulou, Christoforos K. Travlos, Lucas Lage Marinho, Thomas A. Mavrakanas, João Pedro Ferreira, Abhinav Sharma   +5 more
wiley   +1 more source

Age-related changes in corneal thickness and endothelial characteristics

, 2013
Saulius Galgauskas, Dovilė Norvydaitė, Dalia Krasauskaitė, Simona Stech, Rimvydas Stanislovas AšoklisVilnius University Faculty of Medicine, ENT and Eye Diseases Clinic, Vilnius University Hospital Santariskiu Clinic, Center of Eye Diseases ...
Norvydaitė D, Krasauskaitė D, Stech S, Galgauskas S, Ašoklis RS   +4 more
core  

Lipid–Polymeric Nanoencapsulation of Standardized Camellia sinensis Extract Enhances Antiangiogenic Activity and Ocular Biocompatibility

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
Workflow for the synthesis, characterization, and biological evaluation of lipid–polymeric nanoparticles loaded with a chemically standardized Camellia sinensis extract, showing improved colloidal stability, ocular biocompatibility, and antiangiogenic activity. Created by the authors using BioRender.com.
Sarah Kelly Fernandes, Anízio Bastos de Souza, Líbia Andressa Leandro de Paula, Alessandra Cristine de Souza Matavel, Marcos Paulo Gomes Mol, Mariana de Oliveira Almeida, Vanessa Heloísa Ferreira de Faria, Carolina Paula de Souza Moreira   +7 more
wiley   +1 more source

First‐in‐Human Regulatory T Cell‐Derived Exosomes Plus Ranibizumab for Refractory nAMD

Journal of Extracellular Vesicles, Volume 15, Issue 11, November 2026.
ABSTRACT Persistent fluid despite intravitreal anti–vascular endothelial growth factor (VEGF) treatment remains common in neovascular age‐related macular degeneration (nAMD). Regulatory T cell–derived exosomes (TregExo) have preclinical immunomodulatory activity. To evaluate the safety and maximum tolerated dose (MTD) of intravitreal autologous TregExo
Ying Tian, Zhuyun Qian, Shuzhen Fan, Jianmin Wang, Wei Wei, Yong Tao   +5 more
wiley   +1 more source

Simvastatin Modulates Astrocyte and Microglial Reactivity and Aggressive Behavior After Chronic Sleep Deprivation in Rats

Journal of Neuroscience Research, Volume 104, Issue 11, November 2026.
Simvastatin modulates chronic sleep deprivation‐induced glial remodeling and behavioral responses. ABSTRACT Chronic sleep deprivation (SD) disrupts central nervous system homeostasis, promoting behavioral alterations and glial remodeling within limbic structures.
Higor Hernany Dias, Kevin Silva Müller, Gabriela Larissa Lima‐da‐Silva, Stephane da Silva Alves, Tatiane de Camargo Martins, Pedro Tadao Hamamoto Filho, José de Anchieta de Castro e Horta‐Júnior   +6 more
wiley   +1 more source

Adipose‐Derived Mesenchymal Stem Cells: Isolation, Origin, Phenotype Applications, and Challenges

MedComm, Volume 7, Issue 11, November 2026.
Bridging basic biology to clinical translation, this review systematically explores the in vivo origins and evolving isolation techniques of AD‐MSCs. We dissect their diverse phenotype applications orchestrated by immunometabolic reprogramming, mitochondrial transfer, and extracellular vesicles.
Ziyang Liu, Guangming Tu, Chao Wang, Hongyan Zhao, Ziyi Wu, Wei Li, Li Chen, Bailin Niu   +7 more
wiley   +1 more source

Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies

MedComm, Volume 7, Issue 11, November 2026.
Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang, Siwen Wu, Yusi Wang, Die Hu, Li Yang   +4 more
wiley   +1 more source

2.CORNEAL CHANGES IN A SAMPLE OF PSEUDOEXFOLIATION IRAQI PATIENTS

The Iraqi Journal of Medical Sciences, 2019
Background: Pseudoexfoliation syndrome is a common eye disorder that can affect different parts of the eye causing significant morbidity. Objective: To compare corneal endothelial changes between patients with pseudoexfoliation syndrome and normal age ...
Ahmed M. Rasheed, Diyar J. Kadum
doaj  

High Doses of N‐Acetyl‐P‐Aminophenol Cause Acute Changes in Electroencephalographic and Electrocardiographic Activities in Wistar Rats

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 5, November 2026.
ABSTRACT N‐acetyl‐p‐aminophenol (APAP), or acetaminophen, is the most prescribed analgesic and antipyretic, even used in association with other drugs. Because it is easily bought in drugstores, much evidence about its toxic effects is known due to high doses or continuous use, which can lead to death in cases of intoxication.
Alex Luiz Menezes da Silva, Luiz Gustavo dos Reis de Freitas, Akira Otake Hamoy, Clarissa Araujo da Paz, Luan Oliveira Ferreira, Esther Padilha da Silveira, Maria Klara Otake Hamoy, Nilton Akio Muto, Dielly Catrina Favacho Lopes, Moisés Hamoy   +9 more
wiley   +1 more source

Divergence Between Marker Expression and Phenotype During Human Corneal Endothelial Cell Expansion. [PDF]

Invest Ophthalmol Vis Sci
Bonelli F, Bailey T, Dzivite I, Temmerman L, Dickman M, LaPointe V.   +5 more
europepmc   +1 more source