Results 41 to 50 of about 5,519,513 (263)
Oligopeptide-mediated gene transfer into mouse corneal endothelial cells: Expression, design optimization, uptake mechanism and nuclear localization [PDF]
, 2009 Copyright © The Author 2009. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses?by-nc/2.0/uk/) which permits ...
Seow, WY, George, AJT, Yang, Y-Y
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Proliferative capacity of corneal endothelial cells [PDF]
Experimental Eye Research, 2012 The corneal endothelial monolayer helps maintain corneal transparency through its barrier and ionic "pump" functions. This transparency function can become compromised, resulting in a critical loss in endothelial cell density (ECD), corneal edema, bullous keratopathy, and loss of visual acuity.
openaire +2 more sources
Cryoprotectants for the vitrification of corneal endothelial cells
Cryobiology, 2009 The objective of this work was to select and test systematically possible cryoprotective agents (CPAs) and to obtain a suitable formula for vitrification of corneal endothelial cells (CECs). Fresh bovine CECs were isolated and tested with an optimized vitrification protocol with multi-step CPA loading and removal.
Fan, W, Ma, X, Ge, D, Liu, T, Cui, Z
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Cell Transplantation, 2016 The corneal endothelium plays a primary role in maintaining corneal homeostasis and clarity and must be surgically replaced with allogenic donor corneal endothelium in the event of visually significant dysfunction.
Ricardo F. Frausto +2 more
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Cell & Bioscience, 2023 Abstract Background Research on human pluripotent stem cells (hPSCs) has shown tremendous progress in cell-based regenerative medicine. Corneal endothelial dysfunction is associated with the loss and degeneration of corneal endothelial cells (CECs), rendering cell replacement a promising therapeutic strategy. However, comprehensive preclinical
Juan Yu +13 more
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Research progress of corneal endothelial cell regeneration and replacement
Eye & ENT ResearchCorneal endothelial cells (CECs) are crucial for the maintenance of corneal transparency and normal visual function. Corneal endothelial dysfunction can lead to corneal edema, opacity, and even blindness.
Zongyi Li, Haoyun Duan, Qingjun Zhou
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Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
PLoS ONE, 2019 ObjectiveWe aimed to investigate the functionality of human decellularized stromal laminas seeded with cultured human corneal endothelial cells as a tissue engineered endothelial graft (TEEK) construct to perform endothelial keratoplasty in an animal ...
Francisco Arnalich-Montiel +10 more
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Corneal Changes in Diabetic Patients after Manual Small Incision Cataract Surgery [PDF]
Journal of Clinical and Diagnostic Research, 2014 Background: Diabetics have abnormal corneal morphology along with higher rate of corneal endothelial cell loss and decreased corneal endothelial cell density and early onset of cataract. Aim: To evaluate the changes in corneal endothelium and corneal
Renu Dhasmana +2 more
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Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
wiley +1 more source