Results 41 to 50 of about 210,019 (257)
Work, consumption and subjectivity in postwar France: Moulinex and the meanings of domestic appliances, 1950s-1970s [PDF]
This article responds to some of the limitations of the historiography of consumption in contemporary Europe, notably its tendency to divorce consumer culture from production and to subscribe, in some cases at least, to a rather schematic model of ...
Clarke, J.
core +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Annotated Bibliography of Educational Materials on Legal Ethics [PDF]
Rhode presents an annotated bibliography that includes references to written and audiovisual materials for legal ethics courses and curricular integration ...
Rhode, Deborah L.
core +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Narrative environments: how do they matter? [PDF]
The significance and possible senses of the phrase 'narrative environment' are explored. It is argued that 'narrative environment' is not only polysemous but also paradoxical; not only representational but also performative; and not just performatively ...
Parsons, Allan
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
(Excerpt) In his classic work on stewardship Helge Brattgard said that it is only as the Spirit of God, working through Word and Sacrament, leads [people] to be grateful for spiritual and material gifts received, and to see their responsibility for the ...
Smith, Ralph F
core +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Corporate communications: audiences, funding and crisis management [PDF]
Who are the key audiences of corporate communications? Is the communication department adequately funded? And how are crisis handled? This paper reports an empirical research conducted in 20 British organisations, with a focus on these three questions ...
Dolphin, R, Fan, Y
core

