Results 21 to 30 of about 42,401 (241)

Obesity Associated Cerebral Gray and White Matter Alterations Are Interrelated in the Female Brain. [PDF]

open access: yesPLoS ONE, 2014
Obesity is known to affect the brain's gray matter (GM) and white matter (WM) structure but the interrelationship of such changes remains unclear. Here we used T1-weighted magnetic resonance imaging (MRI) in combination with voxel-based morphometry (VBM)
Karsten Mueller   +7 more
doaj   +1 more source

A CRISPR-strategy for the generation of a detectable fluorescent hESC reporter line (WAe009-A-37) for the subpallial determinant GSX2

open access: yesStem Cell Research, 2020
GSX2 is a homeobox transcription factor (TF) controlling the specification of the ventral lateral ganglionic eminence and its major derivative, the corpus striatum. Medium spiny neurons (MSNs) represent the largest cell component of the striatum and they
Dario Besusso   +8 more
doaj   +1 more source

Glutamate (mGluR-5) gene expression in brain regions of streptozotocin induced diabetic rats as a function of age: role in regulation of calcium release from the pancreatic islets in vitro

open access: yesJournal of Biomedical Science, 2009
Metabotrophic glutamate receptors (mGluRs) modulate cellular activities involved in the processes of differentiation and degeneration. In this study, we have analysed the expression pattern of group-I metabotropic glutamate receptor (mGlu-5) in cerebral ...
Paulose CS   +2 more
doaj   +1 more source

Targeting mGlu5 metabotropic glutamate receptors in the treatment of cognitive dysfunction in a mouse model of phenylketonuria [PDF]

open access: yes, 2018
We studied group-I metabotropic glutamate (mGlu) receptors in Pah(enu2) (ENU2) mice, which mimic the genetics and neurobiology of human phenylketonuria (PKU), a metabolic disorder characterized, if untreated, by autism, and intellectual disability (ID ...
Battaglia, Giuseppe   +12 more
core   +2 more sources

A structural magnetic resonance imaging study in transgender persons on cross-sex hormone therapy [PDF]

open access: yes, 2016
<b><i>Background:</i></b> To date, research findings are inconsistent about whether the neuroanatomy in transgender persons resembles that of their natal sex or their gender identity.
Landré, Lionel   +3 more
core   +2 more sources

Dopamine-D1 and δ-opioid receptors co-exist in rat striatal neurons [PDF]

open access: yes, 2006
Cocaine’s enhancement of dopaminergic neurotransmission in the mesolimbic pathway plays a critical role in the initial reinforcing properties of this drug. However, other neurotransmitter systems are also integral to the addiction process.
Ambrose-Lanci, L. M.   +3 more
core   +2 more sources

Partial Reversal of Striatal Damage by Palmitoylethanolamide Administration Following Perinatal Asphyxia

open access: yesFrontiers in Neuroscience, 2020
Perinatal asphyxia (PA) is a clinical condition brought by a birth temporary oxygen deprivation associated with long-term damage in the corpus striatum, one of the most compromised brain areas.
Lucas D. Udovin   +12 more
doaj   +1 more source

Diabetic Striatopathy

open access: yesActa Médica Portuguesa, 2021
N/a.
Phronpan Chutpiboonwat   +3 more
doaj   +1 more source

Common and Distinct Functional Brain Networks for Intuitive and Deliberate Decision Making [PDF]

open access: yes, 2019
Reinforcement learning studies in rodents and primates demonstrate that goal-directed and habitual choice behaviors are mediated through different fronto-striatal systems, but the evidence is less clear in humans.
Balleine   +9 more
core   +2 more sources

Region-specific astrogliosis: differential vessel formation contributes to different patterns of astrogliosis in the cortex and striatum

open access: yesMolecular Brain, 2020
Brain injury causes astrocytes to become reactive (astrogliosis). In this study, we compared astrogliosis in acutely injured cortex and striatum of adult FVB/N mice induced by stereotaxic injection of ATP, a component of danger-associated molecular ...
Haijie Yang   +6 more
doaj   +1 more source

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